Ninlib 150 mg Capsule 30's

Ninlib 150 mg Capsule 30's belongs to the class of anticancer drugs called tyrosine kinase inhibitors used in the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). Ph+ CML is a type of blood cancer that causes white blood cells to behave differently.

Ninlib 150 mg Capsule 30's contains Nilotinib which works by blocking the action of an abnormal protein (Bcr-Abl tyrosine kinase) produced by an abnormal Philadelphia chromosome that signals abnormal white blood cells (cancerous cells) to multiply. Thereby, it stops the multiplication and inhibits the growth of cancerous cells and then causes the death of these cells.

Take Ninlib 150 mg Capsule 30's as prescribed. You are recommended to take Ninlib 150 mg Capsule 30's for as long as your doctor has advised it for you based on your medical condition. Sometimes, Ninlib 150 mg Capsule 30's may cause common side effects such as vomiting, nausea, diarrhoea, headache, constipation, tiredness, and muscle and joint pain. Most of these side effects of Ninlib 150 mg Capsule 30's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Nilotinib or any other medicines, please tell your doctor. Avoid taking Ninlib 150 mg Capsule 30's if you are pregnant or breastfeeding. You are recommended to use effective contraceptive methods while taking Ninlib 150 mg Capsule 30's and for two weeks after completing the course of Ninlib 150 mg Capsule 30's. Ninlib 150 mg Capsule 30's is not recommended for children below one year of age. Drive only if you are alert as Ninlib 150 mg Capsule 30's may cause dizziness or visual disorders as side effects in some people. If you have yellow skin and eyes, dark-coloured urine, or stomach pain while taking Ninlib 150 mg Capsule 30's, contact your doctor immediately, as these might be symptoms of liver problems. 

Ninlib 150 mg Capsule 30's contains Nilotinib, an anticancer drug used to treat Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). In chronic myeloid leukemia (CML) patients, a change in genetic material (DNA) triggers a signal that tells the body to produce more abnormal white blood cells (cancerous cells). Nilotinib works by blocking this signal and thus stops the production of cancerous cells. Ninlib 150 mg Capsule 30's is used in adults and children with newly diagnosed Ph+ CML in the chronic phase and in adults with Ph+ CML in the accelerated and chronic phase who did not tolerate or no longer benefit from other treatments, including Imatinib. 

• Vomiting
• Nausea
• Diarrhoea
• Headache
• Constipation
• Tiredness
• Muscle and joint pain

If you are allergic to Nilotinib or any other medicines, please tell your doctor. Avoid taking Ninlib 150 mg Capsule 30's if you are pregnant or breastfeeding. You are recommended to use effective contraceptive methods while taking Ninlib 150 mg Capsule 30's and for two weeks after completing the course of Ninlib 150 mg Capsule 30's. Ninlib 150 mg Capsule 30's is not recommended for children below one year of age. Ninlib 150 mg Capsule 30's may affect the growth and development of children with chronic phase Ph+ CML. Some children and adolescents may have slower than normal growth while taking Ninlib 150 mg Capsule 30's. Therefore, your doctor will monitor the growth of your child at regular visits. Drive only if you are alert as Ninlib 150 mg Capsule 30's may cause dizziness or visual disorders as side effects in some people. Ninlib 150 mg Capsule 30's may increase the risk of liver problems, especially in people with a history of liver problems. Therefore, if you have yellow skin and eyes, dark-coloured urine, or stomach pain while taking Ninlib 150 mg Capsule 30's, contact your doctor immediately, as these might be symptoms of liver problems. Inform your doctor if you have a severe problem with lactose (milk sugar) or other sugars as Ninlib 150 mg Capsule 30's may contain lactose. Most people who have mild or moderate lactose intolerance can take Ninlib 150 mg Capsule 30's. Avoid taking Ninlib 150 mg Capsule 30's if you have low levels of magnesium or potassium in the blood or long QTc syndrome. If you have had a surgical procedure involving the removal of the entire stomach (total gastrectomy), inform your doctor before taking Ninlib 150 mg Capsule 30's.

• DISOPYRAMIDE
• QUINIDINE
• AMIODARONE
• SOTALOL
• PROCAINAMIDE
• CLARITHROMYCIN
• MOXIFLOXACIN
• CHLOROQUINE
• HALOPERIDOL
• PIMOZIDE
• METHADONE
• FENTANYL
• ALFENTANIL
• PHENYTOIN
• CARBAMAZEPINE
• PHENOBARBITAL
• WARFARIN
• RIFAMPICIN
• ITRACONAZOLE
• KETOCONAZOLE
• VORICONAZOLE
• CYCLOSPORINE
• TACROLIMUS
• SIROLIMUS

• Ninlib 150 mg Capsule 30's can cause a possibly life-threatening heart problem called QTc prolongation (causes irregular heartbeat, which may lead to sudden death). Therefore, if you faint, feel lightheaded or have an irregular heartbeat while taking Ninlib 150 mg Capsule 30's, please contact your doctor immediately, as these might be symptoms of QTc prolongation.

Regular tests are recommended during treatment with Ninlib 150 mg Capsule 30's:

• To monitor the number of blood cells (red blood cells, white blood cells and platelets), liver and pancreas function in the body to see how Ninlib 150 mg Capsule 30's is tolerated.
• To monitor electrolytes (magnesium, potassium) in the body that are essential in the functioning of the heart.
• To check the level of fats and sugar in the blood.
• Also, ECG is recommended to check the heart rate.

• Drink nutrient-rich liquids such as juices, shakes and soups if you have trouble swallowing solid food.
• Eat frequently by opting for 4 to 6 smaller meals a day instead of 2 to 3 big meals.
• Consume a variety of vegetables, including legumes.
• Eat whole grains, whole fruits, and fat-free or low-fat dairy products.
• Include a variety of proteins in the diet, such as lean meats, poultry, seafood, soy, beans, and eggs.
• Use healthy oils such as olive oil.
• Drink plenty of water to keep yourself hydrated.