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  1. Home
  2. Medicine

  3. Nindev 150 mg Softgel Capsule 10's

Prescription drug
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sureshvarma D , MPharma

Composition :

NINTEDANIB-150MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

MISCELLANEOUS

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad ? 380015 Gujarat, India.
Other Info - NIN0047

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Sureshvarma D

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:40 AM IST

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Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is not known if alcohol interacts with NINDEV 150MG SOFTGEL CAPSULES . However, as a precautionary measure, you are recommended not to consume alcohol with the NINDEV 150MG SOFTGEL CAPSULES to avoid unpleasant side effects.

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Pregnancy

Unsafe

NINDEV 150MG SOFTGEL CAPSULES is listed as pregnancy category D. Because NINDEV 150MG SOFTGEL CAPSULES can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with NINDEV 150MG SOFTGEL CAPSULES .

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether NINDEV 150MG SOFTGEL CAPSULES can be taken by breastfeeding mothers or not.

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Driving

Caution

NINDEV 150MG SOFTGEL CAPSULES may significantly influence your ability to drive and use machines. You should not drive or operate machinery if you feel sick.

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Liver

Caution

Dose adjustment may be needed. NINDEV 150MG SOFTGEL CAPSULES is not recommended for patients with severe hepatic impairment. Please consult your doctor if you have a liver impairment or any concerns.

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Kidney

Caution

Dose adjustment may be needed. NINDEV 150MG SOFTGEL CAPSULES is not recommended for patients with an end-stage renal disease requiring dialysis. Please consult your doctor if you have kidney impairment or any concerns.

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Children

Caution

NINDEV 150MG SOFTGEL CAPSULES is not recommended for children below 18 years as safety and effectiveness have not been established.

Product Substitutes

Reference

  1. https://www.nhs.uk/conditions/idiopathic-pulmonary-fibrosis/treatment/
  2. https://www.medicines.org.uk/emc/product/1786/smpc#gref
  3. https://www.medicines.org.uk/emc/files/pil.1786.pdf

About NINDEV 150MG SOFTGEL CAPSULES

NINDEV 150MG SOFTGEL CAPSULES belongs to the category of 'anti-fibrotic medicine', and it is primarily used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, due to which it gets difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.

NINDEV 150MG SOFTGEL CAPSULES contains 'Nintedanib', which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. NINDEV 150MG SOFTGEL CAPSULES helps in slowing down the progress of idiopathic pulmonary fibrosis.

Always use this medicine as your doctor has told you or per the package leaflet. You must keep to your doctor's instructions to get the maximum benefit. In some cases, you may experience common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking NINDEV 150MG SOFTGEL CAPSULES if you are pregnant or breastfeeding. NINDEV 150MG SOFTGEL CAPSULES may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with NINDEV 150MG SOFTGEL CAPSULES as it could lead to increased dizziness. NINDEV 150MG SOFTGEL CAPSULES is not recommended for children below 18 years as safety and effectiveness have not been established. NINDEV 150MG SOFTGEL CAPSULES is listed as pregnancy category D. Because NINDEV 150MG SOFTGEL CAPSULES can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with NINDEV 150MG SOFTGEL CAPSULES . Consult your doctor if you are breastfeeding; your doctor will decide whether the NINDEV 150MG SOFTGEL CAPSULES can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of NINDEV 150MG SOFTGEL CAPSULES

Idiopathic pulmonary fibrosis

Medicinal Benefits Mweb

Medicinal Benefits

NINDEV 150MG SOFTGEL CAPSULES is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. NINDEV 150MG SOFTGEL CAPSULES can help effectively slow the rate of lung function decline by 50%. NINDEV 150MG SOFTGEL CAPSULES helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. NINDEV 150MG SOFTGEL CAPSULES helps in slowing down the progress of idiopathic pulmonary fibrosis.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of NINDEV 150MG SOFTGEL CAPSULES

  • Diarrhoea
  • Feeling and being sick
  • Tummy (Abdominal) Pain
  • Loss of appetite and weight loss

Drug Warnings

Do not use NINDEV 150MG SOFTGEL CAPSULES if you are allergic to any components present in NINDEV 150MG SOFTGEL CAPSULES . NINDEV 150MG SOFTGEL CAPSULES is listed as pregnancy category D; because NINDEV 150MG SOFTGEL CAPSULES can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with NINDEV 150MG SOFTGEL CAPSULES . Consult your doctor if you are breastfeeding; your doctor will decide whether the NINDEV 150MG SOFTGEL CAPSULES can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. NINDEV 150MG SOFTGEL CAPSULES may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with NINDEV 150MG SOFTGEL CAPSULES as it could lead to increased dizziness. NINDEV 150MG SOFTGEL CAPSULES is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

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NintedanibFosphenytoin
Severe
NintedanibLeflunomide
Severe

Drug-Drug Interactions

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NintedanibFosphenytoin
Severe
How does the drug interact with Nindev 150 mg Softgel Capsule:
Coadministration of Nindev 150 mg Softgel Capsule with Fosphenytoin can reduce the levels of Nindev 150 mg Softgel Capsule. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Nindev 150 mg Softgel Capsule and Fosphenytoin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
NintedanibLeflunomide
Severe
How does the drug interact with Nindev 150 mg Softgel Capsule:
Co-administration of Leflunomide and Nindev 150 mg Softgel Capsule can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Nindev 150 mg Softgel Capsule can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NintedanibPhenytoin
Severe
How does the drug interact with Nindev 150 mg Softgel Capsule:
Coadministration of Phenytoin and Nindev 150 mg Softgel Capsule may decrease the blood levels of Nindev 150 mg Softgel Capsule, which may reduce Nindev 150 mg Softgel Capsule's effectiveness.

How to manage the interaction:
Although taking Phenytoin and Nindev 150 mg Softgel Capsule together can result in an interaction, it can be taken when your doctor has prescribed it. Contact a doctor if your symptoms do not improve. Do not stop taking any drugs without consulting a doctor.
NintedanibLomitapide
Severe
How does the drug interact with Nindev 150 mg Softgel Capsule:
Co-administration of Lomitapide and Nindev 150 mg Softgel Capsule can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Lomitapide and Nindev 150 mg Softgel Capsule can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
NintedanibPrimidone
Severe
How does the drug interact with Nindev 150 mg Softgel Capsule:
Coadministration of Nindev 150 mg Softgel Capsule and primidone can reduce the blood levels of Nindev 150 mg Softgel Capsule.

How to manage the interaction:
Although there is an interaction between Nindev 150 mg Softgel Capsule and primidone, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NintedanibRifapentine
Severe
How does the drug interact with Nindev 150 mg Softgel Capsule:
Coadministration of Nindev 150 mg Softgel Capsule and Rifapentine can reduce the blood levels of Nindev 150 mg Softgel Capsule.

How to manage the interaction:
There may be a possibility of interaction between Nindev 150 mg Softgel Capsule and Rifapentine, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.
NintedanibDexamethasone
Severe
How does the drug interact with Nindev 150 mg Softgel Capsule:
Coadministration of Dexamethasone may lower the blood levels of Nindev 150 mg Softgel Capsule, making the medication less effective in treating your condition.

How to manage the interaction:
Although there is a possible interaction, Dexamethasone can be taken with Nindev 150 mg Softgel Capsule if prescribed by the doctor. Contact a doctor if your symptoms do not improve. Do not discontinue any medications without consulting a doctor.
NintedanibTipranavir
Severe
How does the drug interact with Nindev 150 mg Softgel Capsule:
Coadministration of Nindev 150 mg Softgel Capsule and Tipranavir can reduce the blood levels of Nindev 150 mg Softgel Capsule.

How to manage the interaction:
There may be a possibility of interaction between Nindev 150 mg Softgel Capsule and Tipranavir, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without first consulting your doctor.
NintedanibRifampicin
Severe
How does the drug interact with Nindev 150 mg Softgel Capsule:
Coadministration of Nindev 150 mg Softgel Capsule with Rifampicin can decrease the blood levels of Nindev 150 mg Softgel Capsule, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Nindev 150 mg Softgel Capsule and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
NintedanibPhenobarbital
Severe
How does the drug interact with Nindev 150 mg Softgel Capsule:
Taking Phenobarbital and Nindev 150 mg Softgel Capsule can drastically lower Nindev 150 mg Softgel Capsule levels in the blood, making the medicine less effective in treating the illness.

How to manage the interaction:
Although taking phenobarbital with Nindev 150 mg Softgel Capsule can lead to interaction, they can be taken if recommended by a doctor. Contact a doctor if your symptoms do not improve. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ERYTHROMYCIN
  • CYCLOSPORINE
  • RIFAMPICIN
  • CARBAMAZEPINE
  • PHENYTOIN

Habit Forming

No

Special Advise

  • Regular blood tests and occasional tests of your bone marrow will be carried out to check whether the treatment is working. If it does work, it will usually be taken for life.

Diet & Lifestyle Advise

  • Watch out for triggers that worsen the cough, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking and alcohol.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and vegetable and fruit juices.
  • Avoid processed and refined foods.

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