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Nepzole Tablet 10's

Nepzole Tablet 10's

About Nepzole Tablet 10's

Nepzole Tablet 10's belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus). It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.

Nepzole Tablet 10's contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Take Nepzole Tablet 10's as prescribed. Your doctor will advise you on how often you need to take Nepzole Tablet 10's based on your medical condition. Some people may experience headache, nausea, stomach pain, and diarrhoea. Most of these side effects of Nepzole Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Nepzole Tablet 10's. Avoid breastfeeding while taking Nepzole Tablet 10's as it may be excreted in breast milk. You are recommended to avoid alcohol consumption whilst on treatment with Nepzole Tablet 10's. Nepzole Tablet 10's is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that the benefits outweigh the risks.

Uses of Nepzole Tablet 10's

Systemic fungal infections

Medicinal Benefits

Nepzole Tablet 10's is an antifungal used to treat severe fungal infections. It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks. It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Directions for Use

Take Nepzole Tablet 10's with food to avoid stomach upset or take it as advised by the doctor. Swallow the whole tablet/capsule with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nepzole Tablet 10's

  • Headache
  • Nausea
  • Stomach pain
  • Diarrhoea 

Drug Warnings

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Nepzole Tablet 10's. Avoid breastfeeding while taking Nepzole Tablet 10's as it may be excreted in breast milk. You are recommended to avoid alcohol consumption with Nepzole Tablet 10's. If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

Drug Interactions

Drug-Drug Interaction: Nepzole Tablet 10's may interact with antiarrhythmic agents (quinidine, dofetilide), antipsychotic drugs (pimozide), drugs used to treat heartburn and acidity (omeprazole, cisapride), cholesterol-lowering medicines (simvastatin, lovastatin), medicines used to treat migraine (dihydroergotamine, ergotamine), high blood pressure lowering drugs (nisoldipine, eplerenone) and benzodiazepines (alprazolam, triazolam, midazolam).

Drug-Food Interaction: Nepzole Tablet 10's may interact with caffeine. Therefore, avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola, and energy drinks as it may increase the adverse effects of caffeine. Do not take marijuana with Nepzole Tablet 10's as it may worsen the adverse effects of marijuana. Also, avoid consumption of alcohol with Nepzole Tablet 10's as it may increase the risk of liver damage and cause adverse effects. 

Drug-Disease Interaction: If you have adrenal insufficiency, heart or liver problems, inform your doctor before taking Nepzole Tablet 10's.

Drug-Drug Interactions Checker List

  • QUINIDINE
  • DOFETILIDE
  • PIMOZIDE
  • OMEPRAZOLE
  • CISAPRIDE
  • SIMVASTATIN
  • LOVASTATIN
  • DIHYDROERGOTAMINE
  • ERGOTAMINE
  • NISOLDIPINE
  • EPLERENONE
  • ALPRAZOLAM
  • TRIAZOLAM
  • MIDAZOLAM

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
  • Wear a respiratory mask when there is a risk of exposure to spores.
  • People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
  • Close windows and stay inside during dust storms.
  • Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.

Disease/Condition Glossary

Systemic fungal infections are fungal infections that affect internal organs. The fungus lives in the environment, particularly in moist soil and in decomposing organic matter such as leaves and wood. Fungi enter the body via the paranasal sinuses, gut, lungs, or skin, and may spread to other organs. If these infections are not treated with appropriate therapy or if treatment is delayed, it may lead to medical emergencies. The symptoms of systemic fungal infection in people with normal immune function include cough, fever, or loss of appetite. It can also affect people who are immune compromised.