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Multaq 400Mg Tablet

Multaq 400Mg Tablet

About Multaq 400Mg Tablet

Multaq 400Mg Tablet belongs to a group of medications known as 'anti-arrhythmic' primarily used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow). Besides this, Multaq 400Mg Tablet is also used to treat 'cardioversion' which is a medical procedure that changes the abnormal heartbeat to a normal rhythm. Arrhythmia is a problem associated with the rate of rhythm at which the heartbeats.

Multaq 400Mg Tablet contains 'Dronedarone' a Class III anti-arrhythmic drug that restores normal heart rhythm and reduces heart rate in atrial fibrillation. Multaq 400Mg Tablet blocks abnormal electrical signals in the heart. Also, it prevents ventricular fibrillation (a rapid contraction of heart muscle) and ventricular tachycardia (lower chambers of the heart ventricles that beat quickly than normal).

Take Multaq 400Mg Tablet as prescribed by your doctor. Your dose and duration of Multaq 400Mg Tablet will be advised by your doctor, depending upon your medical condition. In some cases, you may experience slow heartbeat, diarrhoea, nausea and vomiting. Most of these side effects of Multaq 400Mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.  

Please inform your doctor if you are using any prescription, non-prescription drugs, including vitamins and herbal products. Let your doctor know if you have any allergic reactions to Multaq 400Mg Tablet or any other medicines, before starting Multaq 400Mg Tablet. Inform your doctor if you have heart, kidney or liver problems and electrolyte imbalance. It is advised to consult a doctor if you are a pregnant or breastfeeding mother. Multaq 400Mg Tablet is not recommended for use during pregnancy. Do not stop taking Multaq 400Mg Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. 

Uses of Multaq 400Mg Tablet

Arrhythmia (irregular heartbeat).

Medicinal Benefits

Multaq 400Mg Tablet contains Dronedarone, a class III anti-arrhythmic drug. It treats arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow). It blocks abnormal electrical signals in the heart and works by restoring normal heart rhythm. It also prevents ventricular fibrillation (a rapid contraction of heart muscle) and ventricular tachycardia (lower chambers of the heart (ventricles) beat quickly than normal). Multaq 400Mg Tablet is used in cardioversion, a medical procedure that changes the abnormal heartbeat to a normal rhythm.

Directions for Use

Tablet: Take it with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Multaq 400Mg Tablet

  • Slow heartbeat
  • Diarrhoea
  • Increased liver enzymes
  • Nausea
  • Vomiting 
  • Abdominal pain
  • Fatigue

Drug Warnings

Brief your medical history to the doctor if you have any heart problems liver, kidney diseases and electrolyte imbalance (low potassium and magnesium) before starting Multaq 400Mg Tablet. Multaq 400Mg Tablet may affect QT prolongation (heart muscle takes longer than usual to recharge between beats) that can cause serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have heart-related problems like heart failure, slow heartbeat and a family history of heart diseases. Multaq 400Mg Tablet is contraindicated during pregnancy since it has harmful effects on the foetus. Consult your doctor before using Multaq 400Mg Tablet if you are a breastfeeding mother. Do not drive or operate machinery if you experience any side effects that affect your ability to concentrate and drive. Avoid consumption of alcohol with Multaq 400Mg Tablet as it may decrease the efficacy of Multaq 400Mg Tablet. Multaq 400Mg Tablet is not recommended in patients younger than 18 years of age.

Drug Interactions

Drug-Drug Interaction: Multaq 400Mg Tablet may interact with antibiotics (ketoconazole, itraconazole, voriconazole, clarithromycin, erythromycin, telithromycin), HIV drugs (lopinavir, ritonavir, rifampin), fits medicines (carbamazepine, phenobarbital, phenytoin), antidepressants (nefazodone, flibanserin), multiple sclerosis treating drugs (fingolimod), blood thinners (dabigatran) and heart-related drugs (digoxin).

Drug-Food Interaction: Avoid grapefruit and its products to prevent the occurrence of side effects of Multaq 400Mg Tablet.

Drug-Disease Interaction: People with heart problems, liver and kidney diseases, and electrolyte imbalance (low levels of potassium and magnesium) should consult the doctor before taking Multaq 400Mg Tablet. Multaq 400Mg Tablet is contraindicated in patients with class IV heart failure requiring hospitalization or referral to a specialized heart failure clinic. 

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • TELITHROMYCIN
  • LOPINAVIR
  • RITONAVIR
  • RIFAMPIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • PHENYTOIN
  • NEFAZODONE
  • FLIBANSERIN
  • FINGOLIMOD
  • DABIGATRAN
  • DIGOXIN

Habit Forming

No

Diet & Lifestyle Advise

  • Keep your weight under control with BMI 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

Special Advise

  • Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor.
  • Regular monitoring of heart function with ECG or EKG is necessary.
  • Liver and kidney function tests are recommended to rule out any chances of kidney or liver impairment.
  • Regular examinations of your electrolytes like potassium and magnesium are recommended. Prolonged use may decrease the level of potassium and magnesium level in the body. 

Disease/Condition Glossary

Arrhythmia: It is a problem associated with the rate of rhythm at which the heart beats. Generally, in this condition, the heart beats too fast, too slow or with an irregular rate. It can lead to severe heart damage. A cardiac arrhythmia occurs when there are abnormal electrical signals in the heart. When the heart beats too fast, it is known as tachycardia, and if it is too slow, it is called bradycardia. Treatment of arrhythmia includes drugs, medical procedures, implantable devices and sometimes surgery.