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  1. Home
  2. Medicine

  3. Mprila Tablet 10's

Prescription drug
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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Composition :

APREMILAST-30MG

Manufacturer/Marketer :

Mylan Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIPSORIATICS

Country of origin

INDIA

Manufacturer/Marketer address

Mylan Pharmaceuticals Private Limited , Commercial Operations , Prestige Tech Park,Platina-3, 7th to 12th floor, Prestige Tech Park, Kadubesanahalli, Bangalore -560103
Other Info - MPR0023

FAQs

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Limit intake of alcohol, as this may increase the risk of serious side effects.

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Pregnancy

Caution

If you are pregnant, inform your doctor before taking Mprila Tablet . Consult your doctor if you become pregnant while taking Mprila Tablet .

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Breast Feeding

Caution

It is not known whether Mprila Tablet may pass into breast milk or not. If you are breastfeeding, inform your doctor before taking Mprila Tablet .

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Driving

Safe if prescribed

Mprila Tablet has no or negligible influence on the ability to drive and use machines.

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Liver

Caution

Mprila Tablet to be taken with caution, especially if you have a history of liver problems. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

Mprila Tablet to be taken with caution, especially if you have a history of kidney diseases. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Unsafe

Mprila Tablet is not recommended for use in children and adolescents below 17 years.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.3648.pdf
  2. https://www.drugs.com/cdi/apremilast.html

About Mprila Tablet

Mprila Tablet belongs to a class of drugs known as phosphodiesterase 4 (PDE4) inhibitors. It is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. Psoriasis is a chronic, painful, nontransmissible, deactivating and damaging disease. It can happen at any age and is most common in the age group 50 to 69. Psoriatic arthritis is a type of arthritis that some people with psoriasis experience.

Mprila Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor. Mprila Tablet works by blocking the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis (inflammation in the joints in people with psoriasis) and psoriasis (scaly, itchy, and red patches on the skin), and thus, lowers the signs and symptoms of these conditions.

Take Mprila Tablet as prescribed by your doctor. You are advised to take Mprila Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience diarrhoea, vomiting, nausea, weight loss, and back pain. Most of these side effects of Mprila Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Mprila Tablet should not be taken in the conditions like depression as it is getting worse with thoughts of suicide. Before starting Mprila Tablet , please inform your doctor if you have any allergy to Mprila Tablet and its part. Mprila Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Mprila Tablet . Mprila Tablet does not affect the ability to drive and use machines.

Uses of Mprila Tablet

Plaque psoriasis, psoriasis arthritis, and oral ulcers caused by Behcet's disease.

Medicinal Benefits Mweb

Medicinal Benefits

Mprila Tablet is used in treating psoriatic arthritis; it decreases pain and swelling and may help improve flexibility in the affected joints. It is also used to treat moderate to severe plaque psoriasis (skin disease causes red, scaly patches to form on some areas of the body) in people who may benefit from medications). It is used to treat ulcers in the mouth in persons with Behcet's syndrome (a disease that results from blood vessel swelling in the body). Mprila Tablet works by blocking the action of some chemical messengers responsible for inflammation related to psoriatic arthritis and psoriasis, thus lowering the signs and symptoms of these conditions.

Directions for Use

Take Mprila Tablet as prescribed by your doctor. Your doctor determines the dose of the medicine based on your condition. Take Mprila Tablet with or without food. Swallow the Mprila Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Side Effects of Mprila Tablet

  • Diarrhea
  • Vomiting
  • Nausea
  • Weight loss
  • Back pain

Drug Warnings

Inform your doctor before using Mprila Tablet , if you have previously had an allergic reaction (hypersensitivity). Before starting Mprila Tablet , please inform your doctor if you have depression and suicidal thoughts. Inform your doctor before taking Mprila Tablet if you have severe kidney problems. Inform your doctor while taking Mprila Tablet if you lose weight without meaning to. Mprila Tablet should not be taken in conditions like severe diarrhoea, nausea, and vomiting. Mprila Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Mprila Tablet . Patients with rare hereditary galactose intolerance problems, total lactase deficiency or glucose-galactose malabsorption should not take Mprila Tablet .

Drug-Drug Interactions

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ApremilastCarbamazepine
Severe
ApremilastPhenytoin
Severe

Drug-Drug Interactions

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ApremilastCarbamazepine
Severe
How does the drug interact with Mprila Tablet:
Taking Mprila Tablet with carbamazepine can significantly reduce the blood levels of Mprila Tablet, which may make the medication less effective.

How to manage the interaction:
Taking Mprila Tablet with Carbamazepine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ApremilastPhenytoin
Severe
How does the drug interact with Mprila Tablet:
Coadministration of Phenytoin with Mprila Tablet may reduce the blood levels of Mprila Tablet, which may reduce effectiveness in treatment.

How to manage the interaction:
Although taking Phenytoin and Mprila Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
ApremilastFosphenytoin
Severe
How does the drug interact with Mprila Tablet:
Coadministration of Fosphenytoin with Mprila Tablet may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Fosphenytoin and Mprila Tablet together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
ApremilastNevirapine
Severe
How does the drug interact with Mprila Tablet:
Coadministration of Nevirapine with Mprila Tablet may decrease the blood levels of Mprila Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is a possible interaction between Mprila Tablet and Nevirapine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ApremilastRifampicin
Severe
How does the drug interact with Mprila Tablet:
Taking Mprila Tablet with rifampicin can decrease the blood levels of Mprila Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Mprila Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ApremilastMitotane
Severe
How does the drug interact with Mprila Tablet:
Coadministration of Mitotane with Mprila Tablet may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Mprila Tablet and Mitotane together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
ApremilastPrimidone
Severe
How does the drug interact with Mprila Tablet:
Coadministration of Mprila Tablet with primidone may decrease the blood levels of Mprila Tablet, which may make Mprila Tablet less effective in treating.

How to manage the interaction:
Although there is an interaction between Primidone and Mprila Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ApremilastEnzalutamide
Severe
How does the drug interact with Mprila Tablet:
Coadministration of Enzalutamide with Mprila Tablet may reduce the efficacy of treatment.

How to manage the interaction:
Although taking Mprila Tablet and Enzalutamide together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
ApremilastRifabutin
Severe
How does the drug interact with Mprila Tablet:
Coadministration of Mprila Tablet and Rifabutin may reduce the blood levels of Mprila Tablet.

How to manage the interaction:
Although there is a possible interaction between Mprila Tablet and Rifabutin, you can take these medicines together if prescribed by a doctor. In case you experience any symptoms, consult a doctor. Do not discontinue any medications without consulting a doctor.
ApremilastRifapentine
Severe
How does the drug interact with Mprila Tablet:
Rifapentine may decrease the blood levels of Mprila Tablet, which may make Mprila Tablet less effective in treating the condition.

How to manage the interaction:
Although taking Mprila Tablet and Rifapentine together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Habit Forming

No

Special Advise

  • Mprila Tablet is a well-tolerated medicine. Mild stomach upset may arise early during the treatment.
  • Monitor your weight repeatedly as Mprila Tablet may lead to weight loss.
  • Inform your doctor immediately if you experience new or worsened depression, suicidal thoughts, unexplained weight loss, or other mood changes.

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

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