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Minirin 0.1 Tablet 15's

Minirin 0.1 Tablet 15's

About Minirin 0.1 Tablet 15's

Minirin 0.1 Tablet 15's is a hormone analogue that belongs to the class of ‘antihemophilic agents’ primarily used to treat diabetes insipidus, post-hypophysectomy polyuria (extreme urination) polydipsia (extreme thirst), and bedwetting. Diabetes insipidus is a condition in which the body fails to control water balance, resulting in excessive urination. Hypophysectomy is the surgical removal of the hypophysis (pituitary gland).

Minirin 0.1 Tablet 15's contains Desmopressin, a human-made form (synthetic) of Vasopressin. Vasopressin is an antidiuretic (that controls fluid balance) hormone, synthesized in the pituitary gland's hypothalamus. When your body cannot produce enough vasopressin, Minirin 0.1 Tablet 15's is given to replace a low vasopressin level. It mimics the natural hormone, vasopressin and works by reabsorbing water from the kidneys, which controls excessive thirst and urination in diabetes insipidus. It also decreases the amount of urine produced and controls bedwetting in children. Being an anti-haemophilic agent, Minirin 0.1 Tablet 15's also reduces bleeding tendency in haemophilia (bleeding disorder) by promoting the release of blood clotting factors.

Your doctor will decide the dosage depending on your medical condition. The common side effects of Minirin 0.1 Tablet 15's include headache, nausea, abdominal cramp, flushing (sense of warmth in the face, ears, neck, and trunk). Although not everyone experiences these side effects, if they occur, seek medical attention.

Before starting Minirin 0.1 Tablet 15's, let your doctor know if you have any medical history of severe kidney disease or hyponatremia (low sodium levels in your body), extreme thirst, uncontrolled high blood pressure, heart failure, and fluid retention. While using Minirin 0.1 Tablet 15's, limit water and other fluids' intake since it may lead to electrolyte imbalance. Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime, leading to increased urination. Pregnant and breastfeeding women should consult their doctor before using Minirin 0.1 Tablet 15's. Do not take or stop this medicine, if the doctor did not advise you to do so.

Uses of Minirin 0.1 Tablet 15's

Diabetes insipidus, Post-hypophysectomy polyuria (polydipsia), and Bedwetting.

Medicinal Benefits

Minirin 0.1 Tablet 15's is a hormone analogue that treats diabetes insipidus, post-hypophysectomy polyuria (extreme urination) or polydipsia (excessive thirst), and bedwetting. It contains Desmopressin, a synthetic form of Vasopressin (antidiuretic hormone), which mimics the natural hormone, vasopressin and works by limiting the amount of water eliminated in the urine, thus controlling excessive thirst and urination in diabetes insipidus. It also decreases the amount of urine produced, thereby preventing the urinary bladder from filling up at night time and controls bedwetting in children. Being an anti-haemophilic agent, Minirin 0.1 Tablet 15's also reduces bleeding tendency in haemophilia (bleeding disorder) by promoting the release of blood clotting factors. 

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Minirin 0.1 Tablet 15's

  • Headache
  • Nausea
  • Abdominal cramp
  • Flushing (sense of warmth in the face, ears, neck and trunk) 

Drug Warnings

Before starting Minirin 0.1 Tablet 15's, let your doctor know if you have any medical history of severe kidney disease, hyponatremia (low sodium levels in your body), extreme thirst, uncontrolled high blood pressure, heart failure, fluid/mineral imbalance (cystic fibrosis), bleeding/clotting problems, and fluid retention. While using Minirin 0.1 Tablet 15's, limit water and other fluids' intake since it may lead to electrolyte imbalance. Inform your doctor if you have any allergic reactions or lactose intolerance before using Minirin 0.1 Tablet 15's. Please consult your doctor before starting Minirin 0.1 Tablet 15's if you are pregnant, planning to conceive or are a breastfeeding mother. It is not recommended to consume alcohol since it may worsen the side effects and increase urination. 

Drug Interactions

Drug-Drug Interaction: Minirin 0.1 Tablet 15's may interact with fits medicine (lamotrigine), antidepressants (escitalopram, fluoxetine, sertraline), and water pills (furosemide).

Drug-Food Interaction: Avoid alcohol since it may worsen the side effects and increase urination. 

Drug-Disease Interaction: Tell your doctor before taking Minirin 0.1 Tablet 15's if you have a medical history of kidney disease, hyponatremia (low sodium levels in your body), severe thirst, uncontrolled high blood pressure, heart failure, fluid/mineral imbalance (cystic fibrosis), bleeding/clotting problems, and fluid retention. 

Drug-Drug Interactions Checker List

  • LAMOTRIGINE
  • ESCITALOPRAM
  • FLUOXETINE
  • SERTRALINE
  • FUROSEMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Minirin 0.1 Tablet 15's for more than once per day. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Minirin 0.1 Tablet 15's.
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains.
  • Eat at regular intervals.
  • Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime since it can lead to increased urination. 
  • Avoid activities that cause dehydration, such as excessive physical exercise or spending time in the heat.

Special Advise

  • Regular monitoring of electrolytes is essential to rule out chances of fluid imbalance.
  • If you are frequently urinating, it is advised to consult your endocrinologist to check for any hormonal abnormalities.
  • You may also be advised for any CT, or MRI scans to know the functioning of your pituitary gland.
  • Kidney functioning tests may be advised by your doctor to monitor for any renal impairment.

Disease/Condition Glossary

Diabetes insipidus: It is a condition in which the body fails to control fluid balance, resulting in excessive urination. It is caused due to two conditions: A) Central diabetes insipidus is a condition when your pituitary gland cannot produce enough vasopressin (an antidiuretic hormone that maintains fluid balance). B) Nephrogenic diabetes insipidus: Though you make enough vasopressin, your kidneys may not respond to vasopressin that regulates fluid balance.

Hypophysectomy: It is the surgical removal of the hypophysis (pituitary gland) to treat cancerous or benign tumours.

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