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Metrogyl Injection 100 ml

Prescription drug

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Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Santoshini Reddy G , M Pharmacy

Composition :

METRONIDAZOLE-500 MG

Manufacturer/Marketer :

J B Chemicals & Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

NPPA :

Regulated

Therapeutic Class

[ANTIBIOTICS]

Country of origin

India

Manufacturer/Marketer address

Cnergy IT Park, 3rd floor Appa Saheb Marathe Marg, Prabhadevi, Mumbai 400025

Other Info - MET0086

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:46 AM IST

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Alcohol

Safe if prescribed

You are recommended not to consume alcohol along with Metrogyl Injection to avoid unpleasant side effects such as stomach pain, nausea, vomiting, flushing, and headache.

Pregnancy

Consult your doctor

Please consult your doctor. Metrogyl Injection should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

Breast Feeding

Consult your doctor

Consult your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Metrogyl Injection .

Driving

Safe if prescribed

Metrogyl Injection may cause dizziness and drowsiness; thus, avoid operating machinery or driving vehicles unless you are alert.

Liver

Consult your doctor

Metrogyl Injection to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending upon your liver condition.

Kidney

Consult your doctor

Metrogyl Injection to be taken with extreme caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending upon your kidney condition.

Children

Safe if prescribed

Limited information about the use of Metrogyl Injection in paediatric patients. Please seek medical advice. Your doctor will weigh the benefits and risks before prescribing this medicine to your child.

Reference

About Metrogyl Injection

Metrogyl Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby Metrogyl Injection treats bacterial infections.

Metrogyl Injection will be administered by a healthcare professional; do not self-administer. Some common side effects of Metrogyl Injection are nausea, vomiting, diarrhoea, constipation, and injection site reaction. These side effects are temporary and may get resolved after some time. However, if any of the side effects persist or worsen, contact the doctor.

Let your doctor know if you are allergic to metronidazole. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metrogyl Injection as it may cause dizziness and drowsiness. Avoid consumption of alcohol while on treatment with Metrogyl Injection as it may cause unpleasant side effects.

Uses of Metrogyl Injection

Bacterial infections

Medicinal Benefits Mweb

Key Benefits

Metrogyl Injection belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, gynecologic, respiratory infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). Metrogyl Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby Metrogyl Injection treats bacterial infections.

Directions for Use

Metrogyl Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Side Effects of Metrogyl Injection

Nausea
Vomiting
Diarrhoea
Constipation
Injection site reactions

Drug Warnings

Do not take Metrogyl Injection if you are allergic to any of the components. Consult your doctor if you are pregnant, plan to get pregnant or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metrogyl Injection as it may cause dizziness and drowsiness. Inform your doctor if you have bone marrow depression/low blood count, kidney impairment, CNS disorder, liver or heart problems, peripheral neuropathy, epilepsy, Crohn's disease (a condition in which the body attacks the lining of the digestive tract), yeast infection, oedema (swelling), or blood disorders.

Drug-Drug Interactions

MetronidazoleAmprenavir

Critical

MetronidazoleEthanol

Critical

Drug-Drug Interactions

MetronidazoleAmprenavir

Critical

How does the drug interact with Metrogyl Injection 100 ml:
Co-administration of Amprenavir with Metrogyl Injection 100 ml can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metrogyl Injection 100 ml with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

MetronidazoleEthanol

Critical

How does the drug interact with Metrogyl Injection 100 ml:
Drinking alcohol while taking Metrogyl Injection 100 ml can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metrogyl Injection 100 ml with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

MetronidazoleDisulfiram

Critical

How does the drug interact with Metrogyl Injection 100 ml:
Coadministration of Disulfiram with Metrogyl Injection 100 ml can increase the risk of side effects.

How to manage the interaction:
Taking Metrogyl Injection 100 ml and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.

MetronidazoleWarfarin

Severe

How does the drug interact with Metrogyl Injection 100 ml:
Coadministration of Metrogyl Injection 100 ml with warfarin can increase the risk of bleeding.

How to manage the interaction:
There is a possible interaction between Metrogyl Injection 100 ml and warfarin, but they can be taken together if a doctor has prescribed them. Consult a doctor if experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without talking to a doctor.

MetronidazoleBusulfan

Severe

How does the drug interact with Metrogyl Injection 100 ml:
Coadministration of Busulfan and Metrogyl Injection 100 ml may increase the risk of side effects.

How to manage the interaction:
Taking Metrogyl Injection 100 ml and Busulfan together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bruising or bleeding, fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.

MetronidazoleMebendazole

Severe

How does the drug interact with Metrogyl Injection 100 ml:
Coadministration of Metrogyl Injection 100 ml with mebendazole may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Metrogyl Injection 100 ml and mebendazole, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms like fever, body ache, painful red rash, cough, peeling of the skin, or Drooling, contact a doctor immediately. Do not stop using any medications without talking to a doctor.

MetronidazoleFluconazole

Moderate

How does the drug interact with Metrogyl Injection 100 ml:
Co-administration of Fluconazole together with Metrogyl Injection 100 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
-Taking Metrogyl Injection 100 ml with Fluconazole together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Drug-Drug Interactions Checker List

AMPRENAVIR
ANISINDIONE
DICUMAROL
WARFARIN
BCG VACCINE
CHOLERA VACCINE LIVE
TYPHOID VACCINE LIVE
BUSULFAN
DISULFIRAM

Habit Forming

Diet & Lifestyle Advise

It would be best to take probiotics after taking the full course of Metrogyl Injection to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Whole grains like whole-grain bread, and brown rice, should be included in the diet.
Avoid intake of alcoholic beverages with Metrogyl Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Metrogyl Injection in fighting off infections.