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Merinethol 50 mg Tablet 10's

Merinethol 50 mg Tablet 10's

About Merinethol 50 mg Tablet 10's

Merinethol 50 mg Tablet 10's belongs to the class of medication called anticancer drugs used in the treatment of blood cancer. Blood cancer also known as leukaemia, is the cancer of blood cells. It causes excessive production of immature white blood cells by the bone marrow.

Merinethol 50 mg Tablet 10's contains Mercaptopurine that works by interfering with the production of genetic material (DNA and RNA) in the cancer cells that are essential for growth, repair and multiplication of cells. Thus, Merinethol 50 mg Tablet 10's stops multiplication of abnormal cells and leads to the growth of cells in an unbalanced way and causes the death of cells.

Take Merinethol 50 mg Tablet 10's as prescribed by your doctor. You are advised to take Merinethol 50 mg Tablet 10's for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience vomiting, nausea, low red blood cell count, loss of appetite, diarrhoea or inflammation of the mouth. Most of these side effects of Merinethol 50 mg Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Merinethol 50 mg Tablet 10's or any other medicines, please tell your doctor. Avoid taking Merinethol 50 mg Tablet 10's if you are pregnant or breastfeeding and consult a doctor. You are recommended to use effective contraceptive methods while using Merinethol 50 mg Tablet 10's and for 3 months after completing the course of Merinethol 50 mg Tablet 10's to prevent pregnancy. Merinethol 50 mg Tablet 10's should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar. Avoid excessive exposure to sunlight as Merinethol 50 mg Tablet 10's may cause sensitivity to sunlight. You are advised to use a sunscreen with a high protection factor and wear protective clothing while going out. Merinethol 50 mg Tablet 10's may increase the risk of a serious condition called macrophage activation syndrome (over activation of white blood cells associated with inflammation), especially in people with arthritis.

Uses of Merinethol 50 mg Tablet 10's

Blood cancer (Acute lymphoblastic leukaemia) 

Medicinal Benefits

Merinethol 50 mg Tablet 10's contains Mercaptopurine, an anticancer drug used to treat blood cancer. Merinethol 50 mg Tablet 10's interferes with the production of genetic material (DNA and RNA) in the cancer cells essential for growth, repair and multiplication of cells. Thus, Merinethol 50 mg Tablet 10's stops multiplication of abnormal cells and leads to cell's growth in an unbalanced way and causes the death of cells. 

Directions for Use

Take Merinethol 50 mg Tablet 10's with or without food as advised by your doctor preferably 1 hour before or 2 hours after taking milk or dairy products. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Merinethol 50 mg Tablet 10's

  • Nausea
  • Vomiting
  • Low red blood cell count
  • Loss of appetite
  • Diarrhoea
  • Inflammation of the mouth

Drug Warnings

If you are allergic to Merinethol 50 mg Tablet 10's or any other medicines, please tell your doctor. Avoid taking Merinethol 50 mg Tablet 10's if you are pregnant or breastfeeding and consult a doctor. You are recommended to use effective contraceptive methods while using Merinethol 50 mg Tablet 10's and 3 months after completing the course of Merinethol 50 mg Tablet 10's to prevent pregnancy. Merinethol 50 mg Tablet 10's should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar. Merinethol 50 mg Tablet 10's may increase the risk of infections. Therefore, consult your doctor if you notice any infection signs such as urinary problems, sore throat or mouth. Avoid excessive exposure to sunlight as Merinethol 50 mg Tablet 10's may cause sensitivity to sunlight. You are advised to use a sunscreen with a high protection factor and wear protective clothing while going out. Merinethol 50 mg Tablet 10's may increase the risk of a serious condition called macrophage activation syndrome (over activation of white blood cells associated with inflammation), especially in people with arthritis. If you are about to receive any vaccinations, inform your doctor that you are taking Merinethol 50 mg Tablet 10's to cause infections. 

Drug Interactions

Drug-Drug Interaction: Merinethol 50 mg Tablet 10's may interact with medicines used to treat gout (thiopurinol, febuxostat, oxipurinol, allopurinol), anti-inflammatory drugs (mesalazine, sulfasalazine, olsalazine), blood thinner (warfarin, acenocoumarol), a drug used to treat various autoimmune diseases (infliximab), anticonvulsants (phenytoin, carbamazepine), antiviral drug (ribavirin).

Drug- Food Interaction: No interactions found.

Drug-Disease Interaction: If you have TPMT (thiopurine methyltransferase) deficiency, an inherited mutation in the NUDT15-gene (a gene involved in the breakdown of mercaptopurine in the body), Lesch-Nyhan syndrome (a genetic condition), shingles, chickenpox, hepatitis B infection, kidney or liver problems, inform your doctor before taking Merinethol 50 mg Tablet 10's.

Drug-Drug Interactions Checker List

  • FEBUXOSTAT
  • ALLOPURINOL
  • MESALAZINE
  • SULFASALAZINE
  • WARFARIN
  • ACENOCOUMAROL
  • INFLIXIMAB
  • PHENYTOIN
  • CARBAMAZEPINE
  • RIBAVIRIN
  • THIOPURINOL
  • OXIPURINOL
  • OLSALAZINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Merinethol 50 mg Tablet 10's as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Special Advise

  • Regular blood and urine tests are recommended while taking Merinethol 50 mg Tablet 10's to monitor the number of red blood cells, platelets, white blood cells, uric acid levels, kidney or liver functioning.
  • Do not receive any vaccination during treatment without your doctor's approval while taking Merinethol 50 mg Tablet 10's. 

Disease/Condition Glossary

Blood cancer: It is the cancer of blood cells, also known as leukaemia. It causes excessive production of immature white blood cells by the bone marrow. The symptoms include unintentional weight loss, weakness, excessive sweating, tiredness, bone pain, frequent infections, chills or fever, red spots on the skin or painless, swollen lymph nodes, especially in the armpits neck.  The risk factors of leukaemia include smoking, genetic or blood disorders, family history of leukaemia, exposure to high radiation levels, or previous cancer treatment with radiation or chemotherapy.

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