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48 Hrs returnable
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Prescription drug

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VALPROIC ACID-400MG
Sun Pharma Laboratories Ltd.
ORAL
Not Returnable
Apr-24
Prescription drug
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Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - MAC0113

FAQs

MACORATE CR 400MG TABLET decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures.
MACORATE CR 400MG TABLET helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.
MACORATE CR 400MG TABLET limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition which is characterized by intense headaches.
MACORATE CR 400MG TABLET may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.
Use an effective method of contraception during the treatment with MACORATE CR 400MG TABLET. Avoid getting pregnant while taking MACORATE CR 400MG TABLET as it could lead to serious birth defects. Do not stop taking MACORATE CR 400MG TABLET and consult your doctor immediately if you become pregnant.
MACORATE CR 400MG TABLET may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Do not consume alcohol while taking MACORATE CR 400MG TABLET as alcohol can worsen the side effects of the MACORATE CR 400MG TABLET, including sleepiness and dizziness.

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Pregnancy

Unsafe

MACORATE CR 400MG TABLET is a Category D pregnancy drug. It is not recommended for use during pregnancy as it may cause an increase in the risk of a cleft lip, which is a congenital disability in the unborn baby. If you are a female able to have a baby, you must use an effective method of birth control (contraception) without interruption during your entire treatment with MACORATE CR 400MG TABLET.

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Breast Feeding

Caution

MACORATE CR 400MG TABLET passes into breast milk and may harm your infant. Please consult a doctor if you are breastfeeding before taking MACORATE CR 400MG TABLET. Breastfed infants are at risk for valproic acid-induced hepatotoxicity, so infants should be monitored for jaundice and other signs of liver damage during maternal therapy.

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Driving

Caution

MACORATE CR 400MG TABLET may cause dizziness, drowsiness or tiredness in some people. Therefore, avoid driving if you feel drowsy, dizzy or tired after taking MACORATE CR 400MG TABLET.

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Liver

Caution

Inform your doctor before receiving the MACORATE CR 400MG TABLET if you have a history of liver diseases/conditions. Extreme caution is recommended in patients with impaired liver function. Your doctor will weigh the benefits and potential risks before prescribing MACORATE CR 400MG TABLET.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please inform your doctor if you have kidney impairment.

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Children

Consult your doctor

Use is not recommended for children less than ten years. Your doctor will decide the dose based on your child's condition if more than ten years.

About MACORATE CR 400MG TABLET

MACORATE CR 400MG TABLET belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. In addition, MACORATE CR 400MG TABLET also treats manic episodes associated with bipolar disorder. Besides this, it can also prevent migraine symptoms (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state.

MACORATE CR 400MG TABLET contains Valproic acid, which reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. MACORATE CR 400MG TABLET raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. MACORATE CR 400MG TABLET limits the transmission of nerve pain, thereby preventing migraine headaches.

MACORATE CR 400MG TABLET should be taken as prescribed by the doctor. You may sometimes experience nausea, upset stomach or stomach pain, tremors (shakes), sleepiness, headache, weight gain and thinning hair. Most of these side effects are temporary and will go away on their own. However, if you suffer these adverse effects on a regular basis, you should consult your doctor.

Inform your doctor if you are allergic to any components present in MACORATE CR 400MG TABLET. If you are pregnant, do not take MACORATE CR 400MG TABLET because it may cause serious congenital defects. Use effective contraception if you are of childbearing age while taking MACORATE CR 400MG TABLET. If you are breastfeeding, inform your doctor before taking MACORATE CR 400MG TABLET. As MACORATE CR 400MG TABLET causes sleepiness and dizziness, do not drive or operate machinery. Avoid drinking alcohol with MACORATE CR 400MG TABLET as it may cause dizziness and tiredness. To rule out any negative effects, keep your doctor updated about your health condition and medications.

Uses of MACORATE CR 400MG TABLET

Epilepsy (fits), Bipolar disorder, Migraine

Medicinal Benefits Mweb

Medicinal Benefits

MACORATE CR 400MG TABLET contains Valproic acid, an anticonvulsant (or anti-epileptic) medicine that reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. MACORATE CR 400MG TABLET raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. MACORATE CR 400MG TABLET limits the transmission of nerve pain, thereby preventing migraine headaches.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Side Effects of MACORATE CR 400MG TABLET

  • Stomach pain
  • Feeling or being sick
  • Diarrhoea
  • Dry or sore mouth or swollen gums
  • Shakes (tremors) in a part of your body
  • Unusual eye movements
  • Feeling tired or sleepy
  • Headache
  • Weight gain
  • Thinning hair, or changes to the colour or texture of your hair
  • Irregular or delayed periods

Drug Warnings

Before taking the MACORATE CR 400MG TABLET, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby, or are breastfeeding. You should not become pregnant while you are receiving MACORATE CR 400MG TABLET. Consult your doctor immediately if you become pregnant while receiving a MACORATE CR 400MG TABLET. Alcohol should be avoided during treatment with this medicine. You must not drive or operate machinery while receiving MACORATE CR 400MG TABLET.

Drug-Drug Interactions

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Drug-Food Interactions

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Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • WARFARIN
  • ASPIRIN
  • CIMETIDINE
  • RITONAVIR
  • ERYTHROMYCIN
  • VENLAFAXINE
  • QUETIAPINE
  • CHOLESTYRAMINE
  • MEFLOQUINE
  • CHLOROQUINE

Habit Forming

No

Special Advise

  • Blood and urine tests may be affected by the MACORATE CR 400MG TABLET. Inform the person conducting the exams that you will be taking MACORATE CR 400MG TABLET.
  • If you are of childbearing age, utilise effective contraception continuously during your treatment with MACORATE CR 400MG TABLET.
  • Contact your doctor immediately if you become pregnant while taking MACORATE CR 400MG TABLET.

Diet & Lifestyle Advise

  • Adolescents and adults are advised to follow the Atkins diet (high fat, low carbohydrate).
  • Exercising on a regular basis aids with weight maintenance and general health.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and drinking alcohol.
  • Meditation and yoga can help reduce stress, reduce pain sensitivity, and increase coping abilities.
  • Have a seizure response plan in place, and make sure everyone around you knows what to do in the event of a seizure.
  • Prepare your living environment; simple changes may help reduce the risk of physical damage during a seizure.
  • Understand what causes seizures and try to reduce or avoid them.
  • Please keep your overall health in mind, as it can aid in the reduction of seizure activity.
  • Install an alarm or an emergency gadget to summon help during a seizure attack.

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