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Lacosam Injection 20 ml

Lacosam Injection 20 ml

About Lacosam Injection 20 ml

Lacosam Injection 20 ml belongs to the class of anticonvulsants used to treat partial onset seizures (seizures that affect only one portion of the brain) in adults and children one month or older who cannot take oral treatments. Lacosam Injection 20 ml is also used in conjunction with other medications to manage primary generalized tonic-clonic seizures (previously known as a grand mal seizure, a seizure affecting the entire body) in adults and children four years of age and older who are unable to take oral medications. Focal or partial-onset seizures are characterized by abnormal electrical activity in only one brain hemisphere.

Lacosam Injection 20 ml contains lacosamide, which treats seizures by decreasing disorganized electrical activity in the brain.

Lacosam Injection 20 ml is administered by a healthcare professional; do not self-administer. In some cases, you may experience common side effects like coordination problems, double vision, headache, nausea, vomiting, sleepiness, and unsteady walking. Most of these side effects of Lacosam Injection 20 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Don’t stop taking Lacosam Injection 20 ml even if your condition is controlled, as abrupt stopping may cause the recurrence of the seizures. Before taking the Lacosam Injection 20 ml, inform your doctor if you are allergic to lacosamide or other ingredients. Inform your doctor if you are previously diagnosed with depression, kidney or liver impairment, and heart conditions. Before taking Lacosam Injection 20 ml, inform your doctor about your medical history and other medications you are currently taking in order to rule out any potential negative effects.

Uses of Lacosam Injection 20 ml

Focal or partial seizures

Medicinal Benefits

Lacosam Injection 20 ml is an antiepileptic drug, also called anticonvulsants. It treats focal seizures in adults and children above one month of age. Seizures occur due to abnormal electrical activity in the brain. Lacosam Injection 20 ml can inactivate the sodium channels across the neuron membranes. This inactivation decreases neuron signals, thereby decreasing the brain's electrical disturbance or abnormal activity. It can also be used with other medications to manage primary generalized tonic-clonic seizures (Previously known as a grand mal seizure, a seizure affecting the entire body) in adults and children above 4 years of age who cannot take oral medications.

Directions for Use

Lacosam Injection 20 ml is administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lacosam Injection 20 ml

  • Coordination problems 
  • Dizziness
  • Double vision
  • Headache
  • Nausea
  • Vomiting
  • Sleepiness
  • Unsteady walking

Drug Warnings

Consult your doctor immediately if you experience suicidal tendencies. Lacosam Injection 20 ml may cause a reduction in mental awareness; hence, do not drive, operate complex machinery, or engage in other hazardous activities. Do not take Lacosam Injection 20 ml if you are allergic to any of its contents. Inform your doctor before taking Lacosam Injection 20 ml if you have depression, heart problems, kidney and liver problems, have low levels of sodium in your blood, or are taking medicines that could lower the levels of sodium in the blood. Lacosam Injection 20 ml should not be used when pregnancy and lactation unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy or nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Lacosam Injection 20 ml. An ECG is recommended before and after titration to maintain steady-state maintenance in patients. To reduce the risk of increased seizure frequency, Lacosam Injection 20 ml should be progressively discontinued.

Drug Interactions

Drug-drug interactions: Lacosam Injection 20 ml may interact with HIV medications (e.g. atazanavir, saquinavir), opioid medications (e.g. buprenorphine), anticancer medications (e.g. ceritinib), prevent nausea and vomiting caused by cancer chemotherapy (e.g. dolasetron), anaesthetic medications (e.g. ketamine), used to treat multiple sclerosis (e.g. ponesimod, siponimod), medicines used to treat episodes of muscle weakness (e.g. sodium oxybate).

Drug-food interactions: Avoid consumption of alcohol while taking Lacosam Injection 20 ml as it might cause increased dizziness and sleepiness.

Drug-disease interactions: Lacosam Injection 20 ml should be used with caution in patients with depression, renal or hepatic impairment and heart conditions.

Drug-Drug Interactions Checker List

  • ATAZANAVIR
  • SAQUINAVIR
  • BUPRENORPHINE
  • CERITINIB
  • DOLASETRON
  • KETAMINE
  • PONESIMOD
  • SIPONIMOD
  • SODIUM OXYBATE

Habit Forming

No

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps utilize fat instead of glucose for energy generation.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, and sleep well.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures are and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Disease/Condition Glossary

Focal or partial-onset seizures are characterized by abnormal electrical activity in only one brain hemisphere. Common symptoms of focal seizures are involuntary muscle contractions, followed by relaxation on one side of the body, uncontrolled head or eye movements, rapid heart rate, and a tingling sensation on the skin. The symptoms vary in each patient depending on the part of the brain affected.

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