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Written By ,
Reviewed By Hari Kumar , MBBS
48 Hrs returnable
COD available

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PARENTERAL
Not Returnable
Apr-24
ERYTHROPOIESIS STIMULATING AGENTS (ESAs)
India
Other Info - KAB0046

FAQs

It is suggested to store the Kabidarba 25 mcg Injection 0.42 ml in the refrigerator and protect it from light. However, a person should not freeze it.
It is advised to tell your doctor about your medical conditions like heart disease, high blood pressure, kidney disease, a stroke, heart attack, or blood clot, a seizure, a latex allergy to avoid any type of medical condition.
A person who is allergic to any chemical compound present in Kabidarba 25 mcg Injection 0.42 ml or have uncontrolled/untreated high blood pressure, or ever had pure red cell aplasia (a type of anaemia) caused by using darbepoetin alfa, or epoetin alfa is not allowed to take a name.
Consult your doctor before taking Kabidarba 25 mcg Injection 0.42 ml if you are pregnant or planning for pregnancy. Your doctor will prescribe Kabidarba 25 mcg Injection 0.42 ml only if the benefits outweigh the risks.
Kabidarba 25 mcg Injection 0.42 ml contains a protein "Darbepoetin alfa", which works by providing signals to the bone marrow to make more red blood cells. As in chronic kidney disease, the kidney gets damaged and doesn't filter the blood in the way it should be leading to anemia.
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Kabidarba 25 mcg Injection 0.42 ml belongs to the class of medication called 'blood-forming agent'  primarily used to treat anaemia (low red blood cell count) in person with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer (except for bone marrow or blood cells' cancer). Kabidarba 25 mcg Injection 0.42 ml helps to reverse anaemia and reduce the need for blood transfusion. Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia.

Kabidarba 25 mcg Injection 0.42 ml contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. Kabidarba 25 mcg Injection 0.42 ml is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient 'erythropoietin protein' which aids in the formation of red blood cells, Kabidarba 25 mcg Injection 0.42 ml stimulates the production of this protein in the bone marrow. 

Kabidarba 25 mcg Injection 0.42 ml will be injected by the healthcare provider. Do not self-administer. The most common side effects of Kabidarba 25 mcg Injection 0.42 ml are shortness of breath,  cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain. Most of these sides effects of Kabidarba 25 mcg Injection 0.42 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you have uncontrolled/untreated high blood pressure or red cell aplasia (a type of anaemia) due to darbepoetin alfa or epoetin alfa, please inform your doctor before taking Kabidarba 25 mcg Injection 0.42 ml to avoid any complications. Also, mention all the other medications you are taking to affect the way Kabidarba 25 mcg Injection 0.42 ml works. Inform your doctor immediately, if you feel weak, lightheaded, tired, or short of breath, or if your skin looks pale as it may be signs that the body has stopped responding to Kabidarba 25 mcg Injection 0.42 ml. 

Anaemia (in cancer and chronic kidney disease) 

Medicinal Benefits Mweb

Kabidarba 25 mcg Injection 0.42 ml is a human-made form of naturally occurring erythropoiesis-stimulating protein or erythropoietin (a hormone produced by the kidney's specialized cells and is responsible for protecting red blood cells against destruction and also stimulates the cells of bone marrow to produce more amount of red blood cells). Deficiency of erythropoietin happens when a person is suffering from chronic kidney diseases, which in turn cause low red blood cells count causing anaemia.  This medicine is primarily indicated for treating anaemia (low red blood cell count) in persons with long-term serious (chronic) kidney disease and persons receiving chemotherapy for some types of cancer except for bone marrow or blood cells' cancer. Kabidarba 25 mcg Injection 0.42 ml contains a protein 'Darbepoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. 

Kabidarba 25 mcg Injection 0.42 ml will be administered by a healthcare professional; do not self-administer.

  • Shortness of breath
  • Cough
  • Hypotension (low blood pressure)
  • Headache
  • Body aches
  • Diarrhoea
  • Injection site pain 
  • Abdominal pain (stomach pain) 

 

Kabidarba 25 mcg Injection 0.42 ml can enhance the risk of serious heart problems including heart attack so tell your doctor immediately if you notice shortness of breath, sudden numbness or weakness, chest pain, or trouble speaking or understanding. This medicine may also shorten survival time in some people with certain types of cancer. Inform your doctor before taking Kabidarba 25 mcg Injection 0.42 ml if you have heart disease, high blood pressure, kidney disease, stroke, heart attack, blood clot, seizure, or latex allergy. Do not take Kabidarba 25 mcg Injection 0.42 ml if you are pregnant or breastfeeding unless prescribed by the doctor. Kabidarba 25 mcg Injection 0.42 ml may affect a person's ability to drive as it may cause convulsion during initial days of treatment, so a person taking Kabidarba 25 mcg Injection 0.42 ml should avoid driving or operating any machine. Kabidarba 25 mcg Injection 0.42 ml should not be given to children below 12 years of age, as safety and effectiveness have not been established. Avoid consuming alcohol along with Kabidarba 25 mcg Injection 0.42 ml as it could lead to increased dizziness and sleepiness. 

verifiedApollotooltip
Darbepoetin alfaLenalidomide
Severe
Darbepoetin alfaThalidomide
Severe
Darbepoetin alfaLenalidomide
Severe
How does the drug interact with Kabidarba 25 mcg Injection 0.42 ml:
Taking Kabidarba 25 mcg Injection 0.42 ml with Lenalidomide can increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between lenalidomide and Kabidarba 25 mcg Injection 0.42 ml, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Darbepoetin alfaThalidomide
Severe
How does the drug interact with Kabidarba 25 mcg Injection 0.42 ml:
Taking thalidomide together with Kabidarba 25 mcg Injection 0.42 ml may increase the risk of blood clots.

How to manage the interaction:
Although there is a possible interaction between Thalidomide and Kabidarba 25 mcg Injection 0.42 ml, but it can be taken if your doctor has advised it. However, if you experience chest pain shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg; and numbness or weakness on one side of the body, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Darbepoetin alfaPomalidomide
Severe
How does the drug interact with Kabidarba 25 mcg Injection 0.42 ml:
Taking Kabidarba 25 mcg Injection 0.42 ml with Pomalidomide can increase the risk of dangerous blood clots.

How to manage the interaction:
Although there is a possible interaction between Pomalidomide and Kabidarba 25 mcg Injection 0.42 ml, you can take these medicines together if prescribed by a doctor. However, If you experience chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Darbepoetin alfaCarfilzomib
Severe
How does the drug interact with Kabidarba 25 mcg Injection 0.42 ml:
Combining Kabidarba 25 mcg Injection 0.42 ml with Carfilzomib can increase the risk of blood clots.

How to manage the interaction:
Although there is a possible interaction between Carfilzomib and Kabidarba 25 mcg Injection 0.42 ml, you can take these medicines together if prescribed by your doctor. However, if you experience chest pain; shortness of breath; difficulty breathing; coughing up blood; sudden loss of vision; pain, redness, or swelling in an arm or leg; and numbness or weakness on one side of the body, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
  • THALIDOMIDE
  • CYCLOSPORINE
  • CAPTOPRIL
No
  • Certain diagnostic tests like Complete blood count (CBC) can help check the count of red blood cells.
  • Have regular haemoglobin tests to check whether there is an improvement in the level of red blood cells after taking Kabidarba 25 mcg Injection 0.42 ml or not.
  • Limit the consumption of fluids, salt, potassium, phosphorous, and other electrolytes.
  • Eat a low-protein diet, and get enough calories from the foods if you are losing weight.
  • Eat foods that are high in vitamin B12, iron, and folic acid can fulfil the deficiencies of happed in kidney disease.
  • Include a little number of healthy fats in your diet that give you enough energy to be active during the day; however, try to limit fats that make you fatty. Try to include olive oil, peanut oil, and corn oil into your diet.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Using essential oils for massages can help increase circulation.

Kabidarba 25 mcg Injection 0.42 ml Substitute

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