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  3. Ixapana 20Mg Capsule 6'S

Prescription drug
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

PANOBINOSTAT-20MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CHEMOTHERAPY

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - IXA0003

FAQs

Disclaimer

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Alcohol

Caution

Avoid alcohol consumption while on treatment with Ixapana 20Mg Capsule.

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Pregnancy

Unsafe

Ixapana 20Mg Capsule should not be taken during pregnancy as it might cause fetal harm. Inform your doctor immediately if you are conceiving while on therapy.

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Breast Feeding

Unsafe

You should not breastfeed when taking Ixapana 20Mg Capsule as it is unknown if the panobinostat can pass to your baby in the milk.

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Driving

Caution

Ixapana 20Mg Capsule can cause a drop in blood pressure, which can make you feel dizzy, lightheaded or like you are about to faint. If you feel dizzy or lightheaded when taking Ixapana 20Mg Capsule, you should not operate machinery or drive a car.

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Liver

Caution

Caution should be exercised. Monitor hepatic enzymes and adjust the dosage if abnormal liver function tests are observed during panobinostat therapy.

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Kidney

Caution

Limited information is available. Please inform your doctor before prescribing Ixapana 20Mg Capsule if you have kidney impairment. Your doctor will weigh the benefits and potential risks before prescribing Ixapana 20Mg Capsule.

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Children

Consult your doctor

The safety and efficacy of Ixapana 20Mg Capsule in children has not been established.

About Ixapana 20Mg Capsule

Ixapana 20Mg Capsule belongs to the group of anti-cancer medicines used to treat multiple myeloma. Multiple myeloma, also known as myeloma, is a type of bone marrow cancer that affects several areas of the body, such as the spine, skull, pelvis, and ribs.

Ixapana 20Mg Capsule contains Panobinostat. It works by blocking the action of histone deacetylase in myeloma cells. Thereby, it can prevent myeloma cells from growing and multiplying.

Depending on your medical condition, you are advised to take Ixapana 20Mg Capsule for as long as your doctor prescribes it. Sometimes, you may experience common side effects, such as diarrhoea, fatigue, nausea, peripheral oedema, decreased appetite, pyrexia, vomiting and hematologic laboratory abnormalities. Do not be reluctant to talk with your doctor if you persistently experience any of these side effects.

Do not take Ixapana 20Mg Capsule if you are allergic to any of its components or if you are pregnant. Do not try to become pregnant as Ixapana 20Mg Capsule may cause Embryo-Fetal Toxicity. Advise women not to breastfeed while taking Ixapana 20Mg Capsule. Inform your doctor if you are suffering from Hepatic dysfunction, as this increases panobinostat exposure. Your doctor reduces the dose in patients with mild to moderate hepatic (liver) impairment. It is recommended not to be used in people with severe hepatic (liver) impairment. If you feel dizzy or lightheaded when taking panobinostat, you should not operate machinery or drive a car.

Uses of Ixapana 20Mg Capsule

Multiple myeloma

Medicinal Benefits Mweb

Medicinal Benefits

Ixapana 20Mg Capsule contains Panobinostat, which belongs to the anti-cancer medicines used to treat multiple myeloma. It works by blocking the action of histone deacetylase in myeloma cells. Thereby, it can prevent myeloma cells from growing and multiplying.

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Side Effects of Ixapana 20Mg Capsule

  • Nausea
  • Vomiting
  • Appetite loss
  • Feel dizzy
  • Lightheaded
  • Low blood pressure
  • Diarrhea
  • Fatigue (tiredness)
  • Peripheral edema
  • Decreased appetite
  • Pyrexia
  • Vomiting
  • Hematologic laboratory abnormalities

Drug Warnings

Do not take Ixapana 20Mg Capsule if you are allergic to any of its contents. Inform your doctor about your health condition and medications to rule out any side effects/interactions. Always take this medicine exactly as your doctor or healthcare professional has told you. To treat your condition effectually, continue taking Ixapana 20Mg Capsule for as long as your doctor has prescribed. Do not stop Ixapana 20Mg Capsule midway. Talk to your doctor before taking Ixapana 20Mg Capsule if you have severe allergic reactions to Ixapana 20Mg Capsule or other medicines or suffer from any medical illness. Avoid taking Ixapana 20Mg Capsule if you are pregnant or breastfeeding because this Ixapana 20Mg Capsule can cause harmful effects on the unborn baby. Both women and men using this Ixapana 20Mg Capsule should use birth control to avoid pregnancy. Inform your doctor if you have a history of low blood pressure; your doctor will closely monitor and manage it. If you are taking medication to help lower your blood pressure, you may need to reduce or discontinue it while taking panobinostat.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Ixapana 20Mg Capsule:
Taking Rifabutin and Ixapana 20Mg Capsule may significantly reduce the blood levels of Ixapana 20Mg Capsule.

How to manage the interaction:
Taking Rifabutin with Ixapana 20Mg Capsule is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately, iff you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ixapana 20Mg Capsule:
Using Ixapana 20Mg Capsule together with ketorolac may increase the risk of bleeding.

How to manage the interaction:
Although taking Ketorolac and Ixapana 20Mg Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ixapana 20Mg Capsule:
Co-administration of Ixapana 20Mg Capsule with clofazimine can increase the risk of irregular heart rhythms. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhoea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Ixapana 20Mg Capsule with clofazimine together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ixapana 20Mg Capsule:
Co-administration of Ixapana 20Mg Capsule with Doxepin can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Ixapana 20Mg Capsule with Doxepin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Ixapana 20Mg Capsule:
Coadministration of Enoxaparin and Ixapana 20Mg Capsule can increase the risk or severity of bleeding complications.

How to manage the interaction:
Although taking Enoxaparin and Ixapana 20Mg Capsule together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any symptoms like bleeding, bruising, dizziness, severe headache red or black stools, vomiting, or weakness it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ixapana 20Mg Capsule:
Coadministration of Amitriptyline and Ixapana 20Mg Capsule may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amitriptyline with Ixapana 20Mg Capsule may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Ixapana 20Mg Capsule:
Using Ixapana 20Mg Capsule together with Moxifloxacin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Moxifloxacin with Ixapana 20Mg Capsule can result in an interaction, but it can be taken if a doctor has advised it. If you experience irregular heart rhythm, dizziness, or shortness of breath, call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Ixapana 20Mg Capsule:
Use of Ixapana 20Mg Capsule with etodolac may increase the risk of bleeding and severe hemorrhage.

How to manage the interaction:
Taking Etodolac with Ixapana 20Mg Capsule together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ixapana 20Mg Capsule:
The use of Ixapana 20Mg Capsule with aspirin may increase the risk of bleeding.

How to manage the interaction:
Taking Ixapana 20Mg Capsule with aspirin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ixapana 20Mg Capsule:
Taking Clopidogrel together with Ixapana 20Mg Capsule can increases the risk of bleeding.

How to manage the interaction:
Although taking Clopidogrel together with Ixapana 20Mg Capsule can result in interaction, it can be taken if prescribed by a doctor. However, consult your doctor immediately if you experience dizziness, lightheadedness, redness or blackness, sticky stools, or severe headache. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Habit Forming

No

Special Advise

  • Monitoring of complete blood count while taking Ixapana 20Mg Capsule is advised.
  • Drink plenty of fluids to prevent urinary problems.
  • If you are due to have any surgery, inform the doctor that you are taking Ixapana 20Mg Capsule.
  • Insomnia or difficulty sleeping at night is a common side effect of panobinostat. This may be minimised by taking panobinostat in the morning.

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

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