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  1. Home
  2. Medicine

  3. Helios Bronac-20% Injection 5ml

Prescription drug
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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Composition :

ACETYLCYSTEINE-20%W/V

Manufacturer/Marketer :

Healers Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIDOTES

Country of origin

INDIA

Manufacturer/Marketer address

Muttaqi Mansion, 57- Mozang Road, Opposite Ganga Ram Hospital (Outdoor Gate), Lahore
Other Info - BRO0116

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:46 AM IST

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Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Interaction of alcohol with Helios Bronac-20% Injection 5ml is unknown. Please consult a doctor before consuming alcohol with Helios Bronac-20% Injection 5ml.

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Pregnancy

Caution

Helios Bronac-20% Injection 5ml is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Helios Bronac-20% Injection 5ml is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Safe if prescribed

Helios Bronac-20% Injection 5ml usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Helios Bronac-20% Injection 5ml should be used with caution if you have a history of Liver diseases/conditions. Your doctor will decide to administer Helios Bronac-20% Injection 5ml if the benefits are greater than the risks.

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Kidney

Caution

Helios Bronac-20% Injection 5ml should be used with caution if you have a history of Kidney diseases/conditions. Your doctor will decide to administer Helios Bronac-20% Injection 5ml if the benefits are greater than the risks.

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Children

Caution

Helios Bronac-20% Injection 5ml is given to children in doses advised by a doctor based on child’s age and weight.

Product Substitutes

Reference

  1. https://www.nps.org.au/assets/medicines/b05f36a6-39c8-422c-99be-a53300ff3bcf.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021539s004lbl.pdf
  3. https://www.medsafe.govt.nz/Profs/Datasheet/a/Acetylcysteineinj.pdf
  4. https://www.drugs.com/cdi/acetylcysteine-injection.html
  5. https://www.drugs.com/pro/acetylcysteine-injection.html

About Helios Bronac-20% Injection 5ml

Helios Bronac-20% Injection 5ml belongs to a class of drugs called antidotes used to treat Paracetamol (acetaminophen) overdose and prevent liver injury. Paracetamol overdose may occur when the person takes more than 8 Paracetamol tablets in 24 hours accidentally or when intended to cause self-harm. If it is not treated promptly with an antidote, significant overdose can lead to liver failure.

Helios Bronac-20% Injection 5ml contains Acetylcysteine that works by restoring the levels of glutathione, a chemical that eliminates toxic substances.

Helios Bronac-20% Injection 5ml will be administered by a healthcare professional; do not self-administer. Some people may experience inflammation and pain at the injection site, nausea, vomiting, fever, excessive shivering, sweating, bruising, or bleeding more easily than normal. Most of these side effects of Helios Bronac-20% Injection 5ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Helios Bronac-20% Injection 5ml or any other medicines, please tell your doctor. Helios Bronac-20% Injection 5ml is given to children in doses advised by a doctor based on the child’s age and weight. If you are pregnant or breastfeeding, please inform your doctor before taking Helios Bronac-20% Injection 5ml. If you are about to undergo any surgery, inform the anaesthetist or surgeon that you are being treated with Helios Bronac-20% Injection 5ml.

Uses of Helios Bronac-20% Injection 5ml

Paracetamol overdose

Medicinal Benefits Mweb

Medicinal Benefits

Helios Bronac-20% Injection 5ml is an antidote for Paracetamol (acetaminophen) overdose. It works by restoring the body’s glutathione, a chemical that eliminates toxic substances. Also, it protects the liver from damage caused due to high levels of paracetamol. Helios Bronac-20% Injection 5ml is very effective when given within 10 hours of paracetamol overdose.

Directions for Use

Helios Bronac-20% Injection 5ml will be administered by a healthcare professional; do not self-administer.

Side Effects of Helios Bronac-20% Injection 5ml

  • Inflammation and pain at the injection site
  • Nausea
  • Vomiting
  • Fever
  • Excessive shivering
  • Sweating
  • Bruising or bleeding more easily than normal

Drug Warnings

If you are allergic to Helios Bronac-20% Injection 5ml or any other medicines, please tell your doctor. Helios Bronac-20% Injection 5ml is given to children in doses advised by a doctor based on the child’s age and weight. If you are pregnant or breastfeeding, please inform your doctor before taking Helios Bronac-20% Injection 5ml. If you are about to undergo any surgery, inform the anaesthetist or surgeon/dentist that you are being treated with Helios Bronac-20% Injection 5ml. If you have a history of stomach ulcers or have asthma, inform your doctor before taking Helios Bronac-20% Injection 5ml.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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ACETYLCYSTEINE-20%W/VHepatic failure, not elsewhere classified
Severe
ACETYLCYSTEINE-20%W/VAsthma
Moderate

Drug-Diseases Interactions

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ACETYLCYSTEINE-20%W/VHepatic failure, not elsewhere classified
Severe
How does the disease interact with Helios Bronac-20% Injection 5ml:
For individuals who have encephalopathy brought on by hepatic failure, the use of Helios Bronac-20% Injection 5ml should be stopped in order to prevent further nitrogenous material ingestion.

How to manage the interaction:
Helios Bronac-20% Injection 5ml should be discontinued in patients with encephalopathy (permanent or temporary brain damage) due to liver failure.
ACETYLCYSTEINE-20%W/VAsthma
Moderate
How does the disease interact with Helios Bronac-20% Injection 5ml:
When treating asthmatic patients or situations where bronchospasm has occurred in the past, Helios Bronac-20% Injection 5ml should be administered cautiously. When starting and continuing Helios Bronac-20% Injection 5ml medication, patients with asthma should be closely monitored.

How to manage the interaction:
Helios Bronac-20% Injection 5ml should be used with caution in asthma patients or where there is a history of bronchospasm (tightening of muscles lining airways). Asthma patients should be closely monitored during the initiation of and throughout Helios Bronac-20% Injection 5ml therapy.
ACETYLCYSTEINE-20%W/VOther disorders of fluid, electrolyte and acid-base balance
Moderate
How does the disease interact with Helios Bronac-20% Injection 5ml:
Helios Bronac-20% Injection 5ml administered intravenously may lead to fluid overload, which may result in hyponatremia, seizures, and even death.

How to manage the interaction:
To avoid fluid overload, a diluted dose is recommended, especially in patients less than 40 kg and those requiring fluid restrictions.
ACETYLCYSTEINE-20%W/VOther diseases of digestive system
Moderate
How does the disease interact with Helios Bronac-20% Injection 5ml:
Helios Bronac-20% Injection 5ml use may make vomiting worse. The risk of gastrointestinal haemorrhage should be assessed in patients with peptic ulcer disease.

How to manage the interaction:
Patients with peptic ulcer disease should be evaluated for the risk of gastrointestinal bleeding. In case of gastric haemorrhage, Helios Bronac-20% Injection 5ml is advised if your doctor considers benefit for you is greater than risk.

Habit Forming

No

Special Advise

Helios Bronac-20% Injection 5ml may give a false positive result with reagent dipstick tests for urinary ketones. Therefore, inform the lab technician that you are taking Helios Bronac-20% Injection 5ml before undergoing any laboratory tests. 

Diet & Lifestyle Advise

  • Do not take more than the Paracetamol dose mentioned on the label or prescribed by the doctor. 
  • Avoid giving Paracetamol to your child unless it is necessary for their fever or pain. 
  • For children below 2 years, use Paracetamol only in the dose advised by the doctor based on the child’s body weight.
  • Limit or avoid alcohol consumption.

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