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48 Hrs returnable
COD available

Online payment accepted

Prescription drug

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LOMUSTINE-40MG
ORAL
Not Returnable
Apr-24
Prescription drug
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Country of origin

India
Other Info - EST0151

FAQs

Estine Capsule 10's contains Lomustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis.
Estine Capsule 10's may cause or worsen pulmonary toxicity, myelosuppression, nephrotoxicity and hepatotoxicity. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any adverse effects/interactions.

Disclaimer

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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Estine Capsule 10's to prevent serious adverse effects.

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Pregnancy

Unsafe

Estine Capsule 10's is not recommended for use in pregnancy as it may harm your fetus. If you are pregnant or planning pregnancy, inform your doctor before taking Estine Capsule 10's.

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Breast Feeding

Unsafe

Avoid breastfeeding your child while on treatment with Estine Capsule 10's as it causes serious side effects to the baby.

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Driving

Unsafe

Estine Capsule 10's may cause visual disturbances as a side effect. Avoid driving vehicles or operating machines until you are alert.

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Liver

Caution

Estine Capsule 10's may cause hepatotoxicity. If you have a pre-existing or a history of liver disease, inform your doctor before taking Estine Capsule 10's. Your liver function should be monitored carefully before, during and after the treatment with Estine Capsule 10's.

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Kidney

Caution

Estine Capsule 10's and its metabolites are known to be largely eliminated via the kidney, and the risk of adverse responses to this medicine may be higher in patients with impaired renal function. It may cause nephrotoxicity with progressive renal failure and a decrease in kidney size. Hence, if you have a pre-existing or a history of kidney disease, inform your doctor before taking Estine Capsule 10's.

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Children

Caution

Please consult a doctor. Your child's doctor may recommend this medicine based on the age, body weight and disease condition of your child.

About Estine Capsule 10's

Estine Capsule 10's is an anti-cancer medicine used in the treatment of brain tumors. A tumor is defined as the formation of solid mass tissue due to the abnormal growth of cells. Estine Capsule 10's is used in the treatment of primary and metastatic brain tumors along with appropriate surgical or radiotherapeutic procedures. A brain tumor is a serious condition where the cells (cancerous or non-cancerous) grow abnormally in the brain. Estine Capsule 10's is also used in the treatment of Hodgkin’s Disease when used in combination with other chemotherapies.

Estine Capsule 10's contains Lomustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

Estine Capsule 10's may cause certain side effects, such as nausea, vomiting, headache, visual disturbances, blindness, disorientation, lack of energy, loss of control, and difficulty talking. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Estine Capsule 10's should be taken as prescribed by your doctor. Do not take more than the recommended dose of medicine.

Estine Capsule 10's should be avoided if you are allergic to it or any other components present in it. Estine Capsule 10's may cause pulmonary toxicity, delayed myelosuppression, pulmonary fibrosis, nephrotoxicity, and hepatotoxicity in some patients. Hence, careful monitoring should be done during the entire treatment. This medicine is known to cause embryo-fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. It is unknown whether Estine Capsule 10's is suitable for children's use. Hence, please consult your doctor or paediatrician for information on children's use. Breastfeeding should be discontinued in nursing mothers during the treatment. Estine Capsule 10's should only be taken once in 6 weeks as taking more than the recommended dose can cause serious life-threatening problems. Hence, talk to your doctor or pharmacist before starting the treatment. 

Uses of Estine Capsule 10's

Brain Tumors, Hodgkin’s Disease.

Medicinal Benefits Mweb

Medicinal Benefits

Estine Capsule 10's contains Lomustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

Directions for Use

Take Estine Capsule 10's as prescribed by your doctor. Do not take more than the prescribed dose of medicine, as it can cause fatal toxicity. Swallow the medicine as a whole with a glass of water. Do not chew, crush, or break the medicine. This medicine should be taken on an empty stomach 30 minutes before food or at least 2 hours after food. For children who cannot swallow the medicine as a whole, open the capsule and add the powder to a very small amount (1 teaspoon) of applesauce/ice cream and make your child eat all the mixture.

Side Effects of Estine Capsule 10's

  • Nausea
  • Dizziness
  • Headache
  • Vomiting
  • Lack of energy
  • Visual disturbances
  • Loss of balance
  • Difficulty talking
  • Decreased platelet count
  • Blindness

Drug Warnings

Estine Capsule 10's should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. This medicine can cause a severe decrease in the number of blood cells in your bone marrow. A decrease in the number of blood cells in your body may cause certain symptoms and increase the risk of developing a serious infection or bleeding. Before administration, inform your doctor if you have liver/kidney disease, blood disorders, or respiratory conditions. Estine Capsule 10's may cause pulmonary toxicity, delayed myelosuppression, pulmonary fibrosis, secondary malignancies, nephrotoxicity, and hepatotoxicity in some patients. Hence, careful monitoring should be done during the entire treatment. Estine Capsule 10's is known to cause embryo-fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued in nursing mothers during the treatment. Estine Capsule 10's should be given in children only if prescribed by the paediatrician. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects. Estine Capsule 10's may cause visual disturbances as a side effect. Hence, avoid driving vehicles or operating machines until you can see clearly. Estine Capsule 10's should be taken once in 6 weeks only. Hence, talk to your doctor or pharmacist before starting the treatment.

Drug-Drug Interactions

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LomustineBaricitinib
Severe
LomustineEtanercept
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Drug Interactions Checker List

  • CHOLERA VACCINE
  • TYPHOID VACCINE
  • ZIDOVUDINE
  • ABACAVIR

Habit Forming

No

Special Advise

  • A blood test should be performed, such as LFT, RFT, and PFT, to check for liver/kidney function and pulmonary function.
  • Weekly blood tests should be done during the treatment course to check for CBC (Complete blood count).
  • Estine Capsule 10's should not be taken more than the prescribed dose as it can lead to fatal toxicities and death.
  • Estine Capsule 10's should always be taken on an empty stomach only to avoid nausea.
  • The patient's stool, urine and vomit should be discarded carefully by the caregiver. Gloves should be worn to avoid any contamination.

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.