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Prescription drug
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

Manufacturer/Marketer :

Enferma Remedies Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[GASTROINTESTINAL AGENTS]

Country of origin

India
Other Info - ESO0360

Author Details

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FAQs

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Alcohol

Safe if prescribed

Avoid consumption of alcohol while taking Esomne-DSR 40/30 Capsule . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Consult your doctor

Consult your doctor before taking Esomne-DSR 40/30 Capsule if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Esomne-DSR 40/30 Capsule ; your doctor will decide whether Esomne-DSR 40/30 Capsule can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

Esomne-DSR 40/30 Capsule may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking Esomne-DSR 40/30 Capsule if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking Esomne-DSR 40/30 Capsule if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Esomne-DSR 40/30 Capsule should not be given to children as safety and effectiveness were not established.

About Esomne-DSR 40/30 Capsule

Esomne-DSR 40/30 Capsule belongs to a group of gastrointestinal agents used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, peptic ulcers and Zollinger-Ellison syndrome.

Esomne-DSR 40/30 Capsule is a combination of two drugs: Esomeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Esomeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid Domperidone works by increasing the movements and contractions of stomach muscle. Together, Esomne-DSR 40/30 Capsule helps in treating acidity-related problems.

You are advised to take Esomne-DSR 40/30 Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor before taking Esomne-DSR 40/30 Capsule if you are pregnant or breastfeeding. Esomne-DSR 40/30 Capsule may cause dizziness, so drive only if you are alert. Esomne-DSR 40/30 Capsule should not be given to children as safety has not been established. Avoid consuming alcohol and Esomne-DSR 40/30 Capsule as it could lead to increased drowsiness and elevate stomach acid production. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Esomne-DSR 40/30 Capsule

Gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, Stomach ulcers

Medicinal Benefits Mweb

Key Benefits

Esomne-DSR 40/30 Capsule is a combination of two drugs: Esomeprazole and Domperidone. Esomne-DSR 40/30 Capsule is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. It may also be indicated in the treatment of nausea, vomiting, fullness of the stomach, belching, heavy bloating, heartburn, acidity, gas, upper abdominal pain, erosive oesophagitis, and swallowing problems. Esomeprazole is a proton pump inhibitor that blocks an enzyme called gastric proton pump, responsible for acid production. Domperidone is a dopamine antagonist which works by increasing the movements and contractions of stomach muscles. Together, Esomne-DSR 40/30 Capsule helps in treating acidity-related problems.

Directions for Use

Take Esomne-DSR 40/30 Capsule 1 hour prior to food. Swallow Esomne-DSR 40/30 Capsule as a whole with a glass of water; do not chew or crush it.

Side Effects of Esomne-DSR 40/30 Capsule

  • Dry mouth
  • Stomach pain
  • Diarrhoea
  • Headache
  • Flatulence

Drug Warnings

Do not take Esomne-DSR 40/30 Capsule if you are allergic to any of its contents or other proton pump inhibitors (such as pantoprazole, rabeprazole, lansoprazole or omeprazole); if you are taking nelfinavir (used to treat HIV); if you have prolactinoma (tumour of the pituitary gland), blockage in intestines, bleeding in stomach or intestine, moderate to severe liver disease, low level of potassium or magnesium or high levels of magnesium, or heart problems. Inform your doctor before taking Esomne-DSR 40/30 Capsule if you have severe kidney, heart or liver disease, or if you are due to have Chromogranin A blood test; if you have fungal infections, heart problems or HIV infection. Talk to your doctor if you experience weight loss, problems with swallowing, stomach pain, indigestion, vomit food or blood, or if you pass black stools while taking Esomne-DSR 40/30 Capsule . On long-term treatment, Esomne-DSR 40/30 Capsule may cause low magnesium levels, vitamin B12 levels, and might increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Consult your doctor if you are pregnant or breastfeeding. Esomne-DSR 40/30 Capsule may cause dizziness, so drive only if you are alert. Esomne-DSR 40/30 Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Esomne-DSR 40/30 Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid. A prolonged intake of Esomne-DSR 40/30 Capsule is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor. 

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
DomperidoneBepridil
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Esomne-DSR 40/30 Capsule:
Esomne-DSR 40/30 Capsule may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Esomne-DSR 40/30 Capsule with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Esomne-DSR 40/30 Capsule:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Esomne-DSR 40/30 Capsule and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Esomne-DSR 40/30 Capsule:
Combining Mizolastine with Esomne-DSR 40/30 Capsule can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Esomne-DSR 40/30 Capsule and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Esomne-DSR 40/30 Capsule:
Coadministration of Esomne-DSR 40/30 Capsule with Cisapride can increase the blood levels of Esomne-DSR 40/30 Capsule.

How to manage the interaction:
There may be a possibility of interaction between Esomne-DSR 40/30 Capsule and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Esomne-DSR 40/30 Capsule:
Coadministration of Esomne-DSR 40/30 Capsule with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Esomne-DSR 40/30 Capsule and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Esomne-DSR 40/30 Capsule:
Coadministration of Esomne-DSR 40/30 Capsule with Nefazodone can increase the blood levels of Esomne-DSR 40/30 Capsule.

How to manage the interaction:
There may be a possibility of interaction between Esomne-DSR 40/30 Capsule and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Esomne-DSR 40/30 Capsule:
Coadministration of Esomne-DSR 40/30 Capsule with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Esomne-DSR 40/30 Capsule and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Esomne-DSR 40/30 Capsule:
Coadministration of Esomne-DSR 40/30 Capsule with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Esomne-DSR 40/30 Capsule and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Esomne-DSR 40/30 Capsule:
Coadministration of Esomne-DSR 40/30 Capsule with Ritonavir can increase the blood levels of Esomne-DSR 40/30 Capsule.

How to manage the interaction:
There may be a possibility of interaction between Esomne-DSR 40/30 Capsule and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
How does the drug interact with Esomne-DSR 40/30 Capsule:
Coadministration of Esomne-DSR 40/30 Capsule with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Esomne-DSR 40/30 Capsule and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ATAZANAVIR
  • SAQUINAVIR
  • RITONAVIR
  • NELFINAVIR
  • WARFARIN
  • CLOPIDOGREL
  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • FLUCONAZOLE
  • ERLOTINIB
  • TOREMIFENE
  • VANDETANIB
  • VINCAMINE
  • DIAZEPAM
  • PHENYTOIN
  • CILOSTAZOL
  • CISAPRIDE
  • DOLASETRON
  • TACROLIMUS
  • RIFAMPICIN
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • MOXIFLOXACIN
  • PENTAMIDINE
  • TELITHROMYCIN
  • LEVOTHYROXINE
  • METHOTREXATE
  • CITALOPRAM
  • ESCITALOPRAM
  • DIGOXIN
  • HALOFANTRINE
  • HALOPERIDOL
  • PIMOZIDE
  • SERTINDOLE
  • MEQUITAZINE
  • MIZOLASTINE
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • DISOPYRAMIDE
  • DOFETILIDE
  • SOTALOL
  • DILTIAZEM
  • VERAMAPIL

Habit Forming

No

Special Advise

  • Inform your doctor before taking Esomne-DSR 40/30 Capsule if you are due to have Chromogranin A blood test.
  • Esomne-DSR 40/30 Capsule may cause changes in blood tests. Inform the person doing the tests that you are taking Esomne-DSR 40/30 Capsule .

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5minutes every hour by doing brisk walking or stretching.

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