Do not take ESGIPYRIN DS INJECTION 3ML if you are allergic to any of its components; if you have/had gastric/peptic ulcer, active gastrointestinal bleeding, or coronary artery bypass graft surgery. Inform your doctor if you have/had heart problems, liver or kidney problems, heart attack, stroke, blood circulation problems, bowel disorders, bleeding problems, asthma, porphyria, angina, high blood pressure, high levels of fat, diabetes, or Lupus. Consult your doctor if you are pregnant or breastfeeding. Let your doctor know if you are taking any other medicines or supplements. NSAIDs may increase the risk of cardiovascular events, stroke, myocardial infarction, gastrointestinal bleeding, perforation, and ulceration. Hence, caution should be exercised.