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48 Hrs returnable
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Prescription drug

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EPIRUBICIN HYDROCHLORIDE
EPIRUBICIN-10MG
Glenmark Pharmaceutical Ltd
PARENTERAL
Not Returnable
Apr-24
Prescription drug
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Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - EPI0071

FAQs

EPITHRA INJECTION 10MG contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.
EPITHRA INJECTION 10MG can disrupt a woman's natural menstrual cycle (period) and inhibit sperm production in men. However, you should not presume that you cannot become pregnant or that you cannot make someone else pregnant. It may also harm your foetus. Use reliable methods of birth control while on treatment with EPITHRA INJECTION 10MG .

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Alcohol consumption is not recommended.

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Pregnancy

Unsafe

EPITHRA INJECTION 10MG is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving EPITHRA INJECTION 10MG . Use reliable methods of birth control while on treatment with EPITHRA INJECTION 10MG .

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving EPITHRA INJECTION 10MG . Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Not applicable

EPITHRA INJECTION 10MG does not affect your ability to drive.

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Liver

Caution

EPITHRA INJECTION 10MG should be used with caution in patients with liver impairment. However, this medicine is contraindicated in patients with severe liver disease. If you have a pre-existing or a history of liver disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative, if necessary, based on your condition.

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Children

Unsafe

EPITHRA INJECTION 10MG is not recommended for use in children, as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF leading to serious side effects.

About EPITHRA INJECTION 10MG

EPITHRA INJECTION 10MG is an anti-cancer medicine that is used in conjunction with other drugs to treat breast cancer in people who have had tumor removal surgery. EPITHRA INJECTION 10MG is used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer (abnormal growth in the cells of the breast).

EPITHRA INJECTION 10MG contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.

EPITHRA INJECTION 10MG may cause certain side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, tiredness, back pain, diarrhoea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer EPITHRA INJECTION 10MG . So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

EPITHRA INJECTION 10MG should be avoided if you are allergic to it. It is contraindicated in patients having a recent history of myocardial infarction (MI) or heart attack, patients with baseline neutrophil count < 1500 cells/mm3, severe arrhythmias, previous treatment with anthracyclines, and severe hepatic dysfunction. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any medicines such as cardiotoxic drugs (eg, Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), and cimetidine, as it can cause serious adverse effects. EPITHRA INJECTION 10MG is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. EPITHRA INJECTION 10MG is not recommended for children as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF.

Uses of EPITHRA INJECTION 10MG

Breast Cancer

Medicinal Benefits Mweb

Medicinal Benefits

EPITHRA INJECTION 10MG contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. It is used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer.

Directions for Use

A trained healthcare professional will administer EPITHRA INJECTION 10MG . Hence, do not self-administer.

Side Effects of EPITHRA INJECTION 10MG

  • Nausea
  • Abdominal pain
  • Vomiting
  • Dizziness
  • Back pain
  • Pain at the site of injection
  • Red discoloration of urine
  • Loss of appetite
  • Mouth sores
  • Tiredness
  • Weight gain
  • Pale skin

Drug Warnings

EPITHRA INJECTION 10MG should be avoided if you are allergic to it. It is contraindicated in patients having a recent history of myocardial infarction (MI) or heart attack, patients with baseline neutrophil count < 1500 cells/mm3, severe arrhythmias, previous treatment with anthracyclines and severe hepatic dysfunction. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any medicines such as cardiotoxic drugs (e.g., Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), and cimetidine, as it can cause serious adverse effects. EPITHRA INJECTION 10MG is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. EPITHRA INJECTION 10MG is not recommended for children as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF. Do not stop receiving EPITHRA INJECTION 10MG without a doctor’s advice, as it can cause serious health conditions. EPITHRA INJECTION 10MG is known to cause severe life-threatening haematological reactions, tissue necrosis, cardiomyopathy, secondary acute myelogenous leukaemia, and severe myelosuppression in some patients. Hence careful monitoring of the patient is needed while receiving the medicine.

Drug-Drug Interactions

verifiedApollotooltip
EpirubicinZiprasidone
Critical
EpirubicinGatifloxacin
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Drug Interactions Checker List

  • THALIDOMIDE
  • DOXORUBICIN
  • ABIRATERONE
  • TAMOXIFEN
  • LETROZOLE
  • PACLITAXEL
  • DOCETAXEL
  • CIMETIDINE
  • CILNIDIPINE
  • NIFEDIPINE

Habit Forming

No

Special Advise

  • Avoid having intercourse while on treatment with EPITHRA INJECTION 10MG .
  • Regular monitoring of complete blood count  (CBC) and liver function (LFT) is important while receiving EPITHRA INJECTION 10MG .

Diet & Lifestyle Advise

  • Try to eat more healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.
  • Doing meditation and yoga for some time is very effective in helping cancer patients maintain a healthy attitude and body.