ENDOBLOC 10MG TABLET

ENDOBLOC 10MG TABLET belongs to the class of ‘anti-hypertensive drugs’, primarily used to treat high blood pressure in the arteries of lungs (pulmonary arterial hypertension). Hypertension is a medical condition, in which the blood exerts high pressure (force exerted by circulating blood) against the walls of blood vessels. This condition makes the heart to work harder in pumping the blood to the whole body. Pulmonary hypertension affects arteries in the lungs and the right side of the heart.

ENDOBLOC 10MG TABLET contains ‘Ambrisentan,’ which belongs to the class of ‘endothelin receptor blockers’. Ambrisentan works by inhibiting the action of Endothelin, a natural substance that constricts blood vessels and raises blood pressure. ENDOBLOC 10MG TABLET widens the constricted pulmonary arteries (blood vessels that carry blood from the heart to the lungs) and increases blood supply to the lungs, thus lowering the blood pressure.

In some cases, ENDOBLOC 10MG TABLET can cause side effects like headache, dizziness, palpitations, breathlessness, runny nose, feeling sick, diarrhoea, and fatigue. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Please inform your doctor if you are using any prescription, non-prescription drugs, including vitamins and herbal products. Let your doctor know if you have any allergic reactions to ENDOBLOC 10MG TABLET or any other medicines, before starting ENDOBLOC 10MG TABLET. Inform your doctor if you have low blood pressure, lung, heart, kidney or liver problems, and anaemia (lack of blood cells). It is advised to consult a doctor if you are a pregnant or breastfeeding mother. Do not stop taking ENDOBLOC 10MG TABLET without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Do not consume alcohol with ENDOBLOC 10MG TABLET as it may increase the risk of low blood pressure. 

ENDOBLOC 10MG TABLET is an anti-hypertensive medicine that treats high blood pressure in the arteries of lungs (pulmonary arterial hypertension (PAH)). It contains ‘Ambrisentan,’ an endothelin receptor blocker. ENDOBLOC 10MG TABLET works by inhibiting the action of Endothelin, a natural substance that constricts blood vessels and raises blood pressure. In people with PAH, the pulmonary arteries get narrower making the heart work harder to pump blood through them. ENDOBLOC 10MG TABLET widens these constricted arteries and makes it easier for the heart to pump blood, thus lowering the blood pressure.

• Headache
• Dizziness
• Swelling in your hands, legs, ankles, or feet
• Palpitations
• Breathlessness
• Chest pain or discomfort
• Stuffy nose, sinus pain
• Flushing (redness of the skin)
• Feeling sick
• Diarrhoea
• Feeling tired
• Rash

Brief your medical history if you have heart failure, liver or kidney diseases, lung conditions (pulmonary fibrosis), anaemia, oedema (fluid retention) and hypotension (low blood pressure) before starting ENDOBLOC 10MG TABLET. ENDOBLOC 10MG TABLET is contraindicated during pregnancy since it has harmful effects on the foetus. Consult your doctor before using ENDOBLOC 10MG TABLET if you are a breastfeeding mother. Complete the course strictly as suggested by the doctor, even if you feel better, to avoid disease recurrence. Do not drive or operate machinery since ENDOBLOC 10MG TABLET may cause side effects like dizziness and weakness, affecting your ability to concentrate and drive. Avoid consumption of alcohol with ENDOBLOC 10MG TABLET as it may increase the risk of low blood pressure. ENDOBLOC 10MG TABLET is not recommended in patients younger than 18 years of age.

• EPOPROSTENOL
• SILDENAFIL
• RIFAMPICIN
• CYCLOSPORINE
• ILOPROST

• Keep a check on your daily blood pressure and if you notice any fluctuations, please consult a doctor.
• You may be asked by your doctor to undergo blood and urine tests if you have been suffering from vomiting or dehydration.
• If you have diabetes, using ENDOBLOC 10MG TABLET may affect your blood sugar levels. Inform your doctor so that your diabetes medication may be adjusted accordingly.
• Your dietician may prescribe you a suitable exercise program and diet to manage your blood pressure.
• Your doctor may also suggest liver function tests since ENDOBLOC 10MG TABLET may cause a change in liver enzymes.

• Reduce sodium intake in your diet to maintain your blood pressure.
• Eat natural and healthy foods by cutting down on high on sodium processed foods.
• Lose those extra pounds, since being obese can be a risk factor for hypertension.
• Exercise regularly to maintain good heart health.
• Avoid smoking and alcohol intake.
• Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
• Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.
• Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.