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  1. Home
  2. Medicine

  3. Emend 150mg Injection

Prescription drug
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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Composition :

FOSAPREPITANT-150MG

Manufacturer/Marketer :

Msd Pharmaceutical Pvt Ltd

Consume Type :

Parenteral

Return Policy :

Not Returnable

Therapeutic Class

[ANTIEMETICS]

Country of origin

United States
Other Info - EM30342

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:49 AM IST

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Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

The interaction of alcohol with Emend 150mg Injection is unknown. If you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before receiving Emend 150mg Injection. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Consult your doctor

It is unknown whether Fosaprepitant is excreted in breast milk. Hence, if you are a nursing mother, discuss with your doctor about the best way to feed your baby if you receive Emend 150mg Injection.

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Driving

Safe if prescribed

Emend 150mg Injection may cause dizziness or sleepiness in some people. Therefore, if you feel dizzy or sleepy after receiving Emend 150mg Injection, avoid driving or operating machinery.

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Liver

Consult your doctor

If you have liver disease, inform your doctor before receiving Emend 150mg Injection.

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Kidney

Consult your doctor

If you have any kidney problems, inform your doctor before receiving Emend 150mg Injection.

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Children

Safe if prescribed

If you have any concerns regarding the use of Emend 150mg Injection in children, please consult a doctor.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.5947.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210064s000lbl.pdf
  3. https://ec.europa.eu/health/documents/community-register/2017/20170111136630/anx_136630_en.pdf

About Emend 150mg Injection

Emend 150mg Injection belongs to a class of drugs called anti-emetics. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines). Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Emend 150mg Injection contains Fosaprepitant, a neurokinin 1 (NK1) receptor antagonist which is converted to aprepitant in the body. It works by blocking neurokinin 1 receptors (causes a feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting. 

Emend 150mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, Emend 150mg Injection may cause common side effects such as headache, hiccups, tiredness, loss of appetite, indigestion, and constipation. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult your doctor immediately. 

If you are allergic to Fosaprepitant or other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Emend 150mg Injection. Drive only if you are alert after receiving Emend 150mg Injection. If you are taking other prescription or non-prescription medicines, inform your doctor before receiving Emend 150mg Injection.

Uses of Emend 150mg Injection

Chemotherapy-induced nausea and vomiting

Medicinal Benefits Mweb

Key Benefits

Emend 150mg Injection contains Fosaprepitant, an anti-emetic (a drug used to treat nausea and vomiting) which is converted to aprepitant in the body. It works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps prevent nausea and vomiting caused by anti-cancer medicines.

Directions for Use

Emend 150mg Injection will be administered by a healthcare professional; do not self-administer.

Side Effects of Emend 150mg Injection

  • Headache
  • Hiccups
  • Tiredness
  • Loss of appetite
  • Indigestion
  • Constipation

Drug Warnings

If you are allergic to Fosaprepitant or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before receiving Emend 150mg Injection. Drive only if you are alert after receiving Emend 150mg Injection. If you are taking any other prescription or non-prescription medicines, inform your doctor before receiving Emend 150mg Injection. If you are using warfarin (blood thinner), your doctor may recommend blood tests after you receive Emend 150mg Injection to check your blood clotting.

Drug-Drug Interactions

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FosaprepitantFlibanserin
Critical
FosaprepitantPimozide
Critical

Drug-Drug Interactions

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FosaprepitantFlibanserin
Critical
How does the drug interact with Emend 150mg Injection:
Coadministration of Emend 150mg Injection with Flibanserin can increase the levels of Flibanserin in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Emend 150mg Injection with Flibanserin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema, fatigue, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
FosaprepitantPimozide
Critical
How does the drug interact with Emend 150mg Injection:
When Pimozide is taken with Emend 150mg Injection, it can increase the Pimozide levels in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Emend 150mg Injection with Pimozide is not recommended, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, prolonged diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantEliglustat
Critical
How does the drug interact with Emend 150mg Injection:
When Emend 150mg Injection is taken with Eliglustat, can increase Eliglustat levels in the body. This can increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Emend 150mg Injection and Eliglustat, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantLomitapide
Critical
How does the drug interact with Emend 150mg Injection:
When Emend 150mg Injection is taken with Lomitapide, it can increase the levels of Lomitapide. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Emend 150mg Injection with Lomitapide together is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - diarrhea, nausea, vomiting, pain, discomfort, indigestion, constipation, liver damage, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, dark colored urine, bleeding or vomiting - make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
FosaprepitantAstemizole
Critical
How does the drug interact with Emend 150mg Injection:
Coadministration of Emend 150mg Injection with Astemizole can increase the levels of Astemizole in the body. This increases the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Emend 150mg Injection with Astemizole together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantCisapride
Critical
How does the drug interact with Emend 150mg Injection:
Coadministration of Emend 150mg Injection with Cisapride can increase the levels of Cisapride in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Emend 150mg Injection with Cisapride together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantTerfenadine
Critical
How does the drug interact with Emend 150mg Injection:
When Emend 150mg Injection is taken with Terfenadine, it can lower the rate at which Emend 150mg Injection is broken down and increases its levels in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Emend 150mg Injection and Terfenadine together is generally avoided as it can show an interaction, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like Chest discomfort, Shortness of breath, Weakness, or palpitations, it's important to call your doctor right away - they can be serious heart problems. Do not discontinue any medications without consulting a doctor.
FosaprepitantRanolazine
Severe
How does the drug interact with Emend 150mg Injection:
When Emend 150mg Injection is taken with Ranolazine, can increase the levels of Ranolazine in the body. This can increase the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Fosamprepitant with Ranolazine can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop taking any medications without consulting a doctor.
FosaprepitantSuvorexant
Severe
How does the drug interact with Emend 150mg Injection:
Coadministration of Emend 150mg Injection with Suvorexant can increase the levels of Suvorexant in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Emend 150mg Injection with Suvorexant together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantCilostazol
Severe
How does the drug interact with Emend 150mg Injection:
Coadministration of Emend 150mg Injection with Cilostazol can increase the levels of Cilostazol in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Emend 150mg Injection with Cilostazol together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or nausea, diarrhea, bleeding, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • PIMOZIDE
  • ASTEMIZOLE
  • TERFENADINE
  • CISAPRIDE
  • TACROLIMUS
  • EVEROLIMUS
  • CYCLOSPORINE
  • SIROLIMUS
  • FENTANYL
  • ALFENTANIL
  • QUINIDINE
  • ETOPOSIDE
  • IRINOTECAN
  • IFOSFAMIDE
  • ACENOCOUMAROL
  • WARFARIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • TRIAZOLAM
  • PHENOBARBITAL
  • MIDAZOLAM
  • KETOCONAZOLE
  • VORICONAZOLE
  • POSACONAZOLE
  • ITRACONAZOLE
  • NEFAZODONE
  • DILTIAZEM
  • DEXAMETHASONE
  • ALPRAZOLAM
  • TOLBUTAMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy and low-fat diet that includes lots of fruits and vegetables, skinless poultry, lean meats, nuts, fish, whole grains, and plant-based oils, especially in small portions, as it will be easy for digestion.
  • Avoid eating over-sweet food and include more salty food, especially if you have been vomiting. 
  • Increase the intake of fluids. Drink a small amount of water after small intervals to stay hydrated. 
  • Avoid taking greasy or oily foods, as these foods trigger nausea and vomiting. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

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