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  1. Home
  2. Medicine

  3. Dusure-500 Capsule 10's

Prescription drug
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Written By ,
Reviewed By Sunny S , MBBS

Composition :

HYDROXYUREA-500MG

Manufacturer/Marketer :

Nexkem Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Return Policy :

Not Returnable

Therapeutic Class

[ANTIMETABOLITES]

Country of origin

India

Manufacturer/Marketer address

Nexkem Pharmaceuticals Pvt Ltd
Other Info - DUS0017

FAQs

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

The drinking of alcohol (in small amounts) does not appear to affect the safety or usefulness of Dusure-500 Capsule 10's. If taking alcohol more amount then it causes dizziness.

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Pregnancy

Consult your doctor

Dusure-500 Capsule 10's is not safe during pregnancy because it may cause harmful effects to the baby.

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Breast Feeding

Consult your doctor

It is unknown whether Dusure-500 Capsule 10's is excreted in human milk. Please consult a doctor before using Dusure-500 Capsule 10's while breastfeeding.

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Driving

Safe if prescribed

Dusure-500 Capsule 10's may cause dizziness or severe headache. Therefore, drive only if you alert after taking Dusure-500 Capsule 10's.

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Liver

Consult your doctor

If you have any concerns regarding the use of Dusure-500 Capsule 10's in patients with liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Dusure-500 Capsule 10's in patients with kidney problems, please consult a doctor.

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Children

Safe if prescribed

Safety and efficacy of Dusure-500 Capsule 10's have not established for children. Therefore not recommended for children.

Product Substitutes

Reference

  1. https://www.drugs.com/mtm/hydroxyurea.html
  2. https://www.medicines.org.uk/emc/product/271/pil#gref
  3. https://www.webmd.com/drugs/2/drug-7818/hydroxyurea-oral/details

About Dusure-500 Capsule 10's

Dusure-500 Capsule 10's belongs to a group of classes known as an antimetabolite. It is an anticancer medicine used to treat head and neck cancer and sickle cell anemia (blocking the flow of blood that causes pain and organ damage). Head and neck cancer is a disease including abnormal growth of the tissues of the neck and head that may also have the ability to attack or spread to other portions of the body. Sickle cell anemia is a disease in which your body results in abnormally shaped red blood cells. The cells are shaped like a curved or sickle.

In cancer, Dusure-500 Capsule 10's works by blocking an enzyme that is required for growing cells. This prevents the cancer cells from multiplying and growing. In sickle cell disease, it works by increasing fetal hemoglobin (HbF) (hemoglobin of unborn baby) levels in red blood cells (RBCs). This helps the RBCs accept a normal shape, recovers the flow of blood, and protects against problems like painful sickle cell attacks.

Take Dusure-500 Capsule 10's as prescribed by your doctor. You are advised to take Dusure-500 Capsule 10's for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience loss of appetite (feeling unwell and stomach upset), Increased bleeding tendency, nausea, upset stomach, vomiting. Most of these side effects of Dusure-500 Capsule 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting Dusure-500 Capsule 10's, please inform your doctor if you have any allergy, kidney disease, liver disease, injury on your legs, HIV or AIDS, high level of uric acid in your blood, and treatment with chemotherapy or radiation. Dusure-500 Capsule 10's may increase the chances of other cancer. Inform your doctor about this risk. Immediately contact your doctor if you are pregnant because this Dusure-500 Capsule 10's can cause harmful effects on the unborn baby. Both women and men using this Dusure-500 Capsule 10's should use birth control to avoid pregnancy. The use of this Dusure-500 Capsule 10's by either parent may results in birth defects. You should not take this Dusure-500 Capsule 10's during breastfeeding, inform your doctor if you take Dusure-500 Capsule 10's.

Uses of Dusure-500 Capsule 10's

Head and neck cancer and sickle cell anemia (blocking flow of blood that causes pain and organ damage).

Medicinal Benefits Mweb

Key Benefits

Dusure-500 Capsule 10's belongs to a group of the class known as an antimetabolite. It is used to treat head and neck cancer and sickle cell anemia (blocking the flow of blood that causes pain and organ damage). In cancer, Dusure-500 Capsule 10's works by blocking an enzyme that is required for growing cells. This prevents the cancer cells from multiplying and growing. In sickle cell disease, it works by increasing fetal hemoglobin (HbF) (hemoglobin of unborn baby) levels in red blood cells (RBCs). This helps the RBCs accept a normal shape, recovers the flow of blood, and protects against problems like painful sickle cell attacks.

Directions for Use

Take Dusure-500 Capsule 10's as advised by the doctor. Swallow it as a whole with water. Do not crush, break or chew it. Wash your hands before and after handling the bottle containing Dusure-500 Capsule 10's. Crushed or broken pill can be unsafe if it gets in your mouth, nose, eyes, or on your skin. If this happens, wash your skin with water and soap or wash your eyes with water.

Side Effects of Dusure-500 Capsule 10's

  • Loss of appetite (feeling unwell and stomach upset)
  • Increased bleeding tendency
  • Nausea
  • Upset stomach
  • Vomiting

Drug Warnings

Before taking Dusure-500 Capsule 10's inform your doctor if you have any kind of infection because Dusure-500 Capsule 10's may worsen the infections. Talk to your doctor if you have any allergy symptoms. Kidney disease, liver disease, injury on your legs, HIV or AIDS, high level of uric acid in your blood, and treatment with chemotherapy or radiation inform your doctor. Dusure-500 Capsule 10's may increase the chances of other cancer. Inform your doctor about this risk. Immediately contact your doctor if you are pregnant because this Dusure-500 Capsule 10's can cause harmful effects on the unborn baby. Both women and men using this Dusure-500 Capsule 10's should use birth control to avoid pregnancy. The use of this Dusure-500 Capsule 10's by either parent may result in birth defects. You should not take this Dusure-500 Capsule 10's during breastfeeding, inform your doctor if you take Dusure-500 Capsule 10's. If any powder from a damaged pill is leaked, wash it up at once with a wet paper towel and throw the towel away in a closed plastic bag where children cannot get to it.

Drug-Drug Interactions

verifiedApollotooltip
HydroxycarbamideEtanercept
Severe
HydroxycarbamideDeferiprone
Severe

Drug-Drug Interactions

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HydroxycarbamideEtanercept
Severe
How does the drug interact with Dusure-500 Capsule:
Dusure-500 Capsule when used in conjunction with etanercept may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Dusure-500 Capsule with etanercept, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxycarbamideDeferiprone
Severe
How does the drug interact with Dusure-500 Capsule:
Deferiprone can reduce white blood cell count, and taking it with other medications that might similarly influence white blood cell count or bone marrow function may raise the risk. As a result, you may be more susceptible to get serious infections.

How to manage the interaction:
Co-administration of Dusure-500 Capsule with deferiprone can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
HydroxycarbamideLeflunomide
Severe
How does the drug interact with Dusure-500 Capsule:
Dusure-500 Capsule when used with leflunomide may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Dusure-500 Capsule with leflunomide, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxycarbamideVoclosporin
Severe
How does the drug interact with Dusure-500 Capsule:
Dusure-500 Capsule when used with voclosporin may raise the risk of severe infections, some kinds of cancer, including skin cancer and cancer of the lymph glands (lymphoma).

How to manage the interaction:
There may be a possibility of interaction between Dusure-500 Capsule with voclosporin, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxycarbamideNatalizumab
Severe
How does the drug interact with Dusure-500 Capsule:
Taking Dusure-500 Capsule with natalizumab, especially taking both simultaneously, may raise the risk of serious infections, which may lead to infections like progressive multifocal leukoencephalopathy (PML), an uncommon but dangerous viral infection of the brain that can result in impairment.

How to manage the interaction:
Co-administration of Dusure-500 Capsule with natalizumab can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor immediately if you are experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. If you have growing weakness on one side of your body, awkwardness of limbs, visual disruption, disorientation, or changes in thinking, memory, or personality, inform your doctor.
HydroxycarbamideTetracaine
Severe
How does the drug interact with Dusure-500 Capsule:
Tetracaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Dusure-500 Capsule, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Dusure-500 Capsule and tetracaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
HydroxycarbamideDidanosine
Severe
How does the drug interact with Dusure-500 Capsule:
Combining Dusure-500 Capsule with didanosine can have serious consequences on your liver or pancreas. Didanosine may potentially induce lactic acidosis (lactic acid buildup in the body).Lactic acidosis can develop gradually and worsen over time.

How to manage the interaction:
Co-administration of Dusure-500 Capsule with didanosine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms while taking didanosine: strong discomfort in your upper stomach that spreads to your back, rapid heart rate, nausea and vomiting, diarrhoea, lack of appetite, low fever, dark urine, clay-colored faeces, or jaundice (yellowing of the skin or eyes), unusual muscle pain and weakness, trouble breathing, fast or uneven heart rate, stomach pain, and numbness or cold feeling in your arms or legs, contact the doctor immediately.
HydroxycarbamideRopivacaine
Severe
How does the drug interact with Dusure-500 Capsule:
Ropivacaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Dusure-500 Capsule, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Dusure-500 Capsule and ropivacaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
HydroxycarbamideTofacitinib
Severe
How does the drug interact with Dusure-500 Capsule:
Dusure-500 Capsule when used with tofacitinib may raise the risk of severe infections, cancers.

How to manage the interaction:
There may be a possibility of interaction between Dusure-500 Capsule with tofacitinib, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxycarbamideGolimumab
Severe
How does the drug interact with Dusure-500 Capsule:
Dusure-500 Capsule when used with golimumab may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Dusure-500 Capsule with golimumab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DIDANOSINE
  • INDINAVIR
  • ASPIRIN
  • IBUPROFEN
  • DIPHENHYDRAMINE
  • ALLOPURINOL
  • ZOLPIDEM

Habit Forming

No

Special Advise

  • Wash your hands before and after handling the bottle containing Dusure-500 Capsule 10's.
  • Crushed or broken pill can be unsafe if it gets in your mouth, nose, eyes, or on your skin. If this happens, wash your skin with water and soap or wash your eyes with water.

Diet & Lifestyle Advise

  • Take Dusure-500 Capsule 10's at the same time daily, either with or without a meal.
  • It is recommended to remain hydrated and drink a lot of fluids while taking Dusure-500 Capsule 10's.
  • Do not miss any dose and finish the course as recommended by your doctor.
  • Use an efficient method of birth control to prevent pregnancy while taking this Dusure-500 Capsule 10's.
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, blood cell count in your blood.

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