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Duovir Tablet 10's

Duovir Tablet 10's

About Duovir Tablet 10's

Duovir Tablet 10's belongs to the class of medicines called 'anti-retroviral agents', used for the treatment of immunodeficiency virus (HIV) infection. HIV (human immunodeficiency virus) is a virus that attacks the body’s immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). This medicine is not a cure for HIV. It only prevents the virus from multiplying in your body.

Duovir Tablet 10's contains lamivudine and zidovudine. Duovir Tablet 10's works by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Take Duovir Tablet 10's as advised by your doctor. Duovir Tablet 10's may cause common side effects like nausea, diarrhoea, headache, fatigue, cough, a feeling of discomfort, and nasal congestion (stuffy nose). Most of these side effects gradually resolve over time and do not require medical attention. However, if these side effects persist or worsen, please consult your doctor immediately.

Inform your doctor if you are allergic to any of the components in Duovir Tablet 10's. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Let your doctor know if you have kidney, liver, or pancreatic disease. Please tell your doctor if you have a low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), or lactic acidosis.

Uses of Duovir Tablet 10's

Human immunodeficiency virus (HIV) infection.

Medicinal Benefits

Duovir Tablet 10's contains a combination of two medicines, namely: lamivudine and zidovudine, that belong to the group of medications called anti-retroviral agents. Duovir Tablet 10's is primarily used for the treatment of human immunodeficiency virus (HIV) infection. Duovir Tablet 10's works by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Directions for Use

Swallow Duovir Tablet 10's as a whole with a glass of water. Do not chew, crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Duovir Tablet 10's

  • Nausea
  • Diarrhoea
  • Stomach pain
  • Loss of appetite
  • Tiredness
  • Lack of energy
  • Fever (high temperature)
  • Headache
  • Hair loss (alopecia)
  • Fatigue
  • Cough
  • Muscle pain and discomfort
  • Joint pain
  • Feeling of discomfort
  • Difficulty in sleeping (insomnia)
  • Irritated or runny nose

Drug Warnings

Inform your doctor if you are allergic to any of the components in Duovir Tablet 10's. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Let your doctor know if you have kidney, liver, pancreatic, or bone marrow suppression. Please tell your doctor if you have a low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), lactic acidosis, or opportunistic infections. Duovir Tablet 10's may cause muscle disorders, especially when used for a long period. Tell your doctor if you have or have ever had any disease of the muscles or muscle weakness. If you experience muscle pain or muscle weakness, call your doctor immediately.

Drug Interactions

Drug-Drug Interaction: Duovir Tablet 10's may interact with other antiretroviral (didanosine, efavirenz), antibiotic (atovaquone, clarithromycin, ganciclovir), anti-fungal (cotrimoxazole, fluconazole), anti-mycobacterial (rifampicin), anti-convulsants (phenobarbital, phenytoin, valproic acid), anti-histamines (ranitidine, cimetidine), cytotoxics (cladribine), opioids (methadone), uricosuric (probenecid), anti-cancer (methotrexate), anti-lipemic (atorvastatin, fenofibrate), anti-psychotic (clozapine).

Drug-Food Interaction: No interaction found/established. 

Drug-Disease Interaction: Before taking Duovir Tablet 10's, let your doctor know if you have any kidney disease, liver disease, pancreatic disease, bone marrow suppression, low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), lactic acidosis or muscle disorders.

Drug-Drug Interactions Checker List

  • DIDANOSINE
  • EFAVIRENZ
  • ATOVAQUONE
  • CLARITHROMYCIN
  • GANCICLOVIR
  • COTRIMOXAZOLE
  • FLUCONAZOLE
  • RIFAMPICIN
  • PHENOBARBITAL
  • PHENYTOIN
  • VALPROIC ACID
  • RANITIDINE
  • CIMETIDINE
  • CLADRIBINE
  • PROBENECID
  • METHOTREXATE
  • ATORVASTATIN
  • FENOFIBRATE
  • CLOZAPINE

Habit Forming

No

Diet & Lifestyle Advise

  • Take a diet high in vegetables, fruits, whole grains, and legumes.
  • Choose lean, low-fat sources of protein.
  • Limit sweets, soft drinks, and foods with added sugar. 
  • Take proteins, carbohydrates, and a good little fat in all meals and snacks in your regular diet.
  • Avoid eating raw eggs, meats, or seafood (including sushi and oysters/shellfish).
  • Wash fruits and vegetables thoroughly.
  • Use a separate cutting board for raw meats.
  • Wash hands, utensils, and cutting boards with soap and water after each use.
  • Exercise regularly. 
  • Avoid excessive alcohol and quit smoking.

Special Advise

  • Skipping doses of Duovir Tablet 10's may increase the risk of treatment failure. Make sure that you take all your doses at the correct time.
  • Always practice safe sex while taking Duovir Tablet 10's. Do not share needles or personal items that can have blood or body fluids on them.
  • Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor because Duovir Tablet 10's may cause the weakening of your bones.

Disease/Condition Glossary

HIV (human immunodeficiency virus): HIV (human immunodeficiency virus) is a virus that attacks the body's immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). There is currently no effective cure. Once people get HIV, they have it for life. But with proper medical care, HIV can be controlled. Symptoms include swollen lymph nodes, recurrent fevers, night sweats, fatigue, nausea, vomiting, diarrhoea, weight loss, skin rashes, recurrent oral or vaginal yeast infections, and pneumonia. The human immunodeficiency virus causes HIV infection. You can get HIV from contact with infected blood, semen, or vaginal fluids. Most people get the virus by having unprotected sex with someone who has HIV.