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  1. Home
  2. Medicine

  3. Donect M Plus Tablet 10's

Prescription drug
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Written By ,
Reviewed By Sunny S , MBBS

Composition :

DONEPEZIL-10MG + MEMANTINE-10MG

Manufacturer/Marketer :

Tripada Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

CENTRAL NERVOUS SYSTEM AGENTS

Country of origin

India

Manufacturer/Marketer address

3 Yogi Complex, Nr Doordarshan, Kendra, Thaltej, Ahmedabad, India 380054.
Other Info - DON0125

FAQs

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Taking alcohol, along with Donect M Plus Tablet , may increase its drowsiness effect and cause excessive sleepiness.

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Pregnancy

Caution

Donect M Plus Tablet is a pregnancy category C drug. It is not known whether it will harm the baby. So, take only if prescribed by a doctor.

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Breast Feeding

Caution

It is not known whether Donect M Plus Tablet passes through breast milk or not. So, caution should be exercised if you are breastfeeding.

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Driving

Unsafe

Donect M Plus Tablet is known to cause drowsiness, so please do not drive a car or operate any machinery which requires mental alertness.

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Liver

Caution

Donect M Plus Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Donect M Plus Tablet to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Caution

The safety and efficacy of Donect M Plus Tablet in children have not been established.

Product Substitutes

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/206439lbl.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020690s035,021720s008,022568s005lbl.pdf
  3. https://www.drugs.com/mtm/donepezil-and-memantine.html

About Donect M Plus Tablet

Donect M Plus Tablet is a combination drug containing a 'neurological medicine,' primarily used to treat Alzheimer's disease (memory loss). Alzheimer's disease is a progressive neuro disorder that affects the brain. It causes the brain to shrink (atrophy) and brain cells (neurons) to die. 

Donect M Plus Tablet is a combination medication containing Donepezil and Memantine, which treat Alzheimer’s disease. Donepezil is a cholinesterase inhibitor that works by preventing the breakdown of the chemical acetylcholine and improving the function of nerve cells in the brain. Memantine works by lowering the level of the chemical in the brain which is responsible to cause symptoms of Alzheimer's disease. Together, both of them balance the levels of chemical messengers in the brain and help transmit nerve signals.

Take Donect M Plus Tablet as prescribed by your doctor. You are advised to take Donect M Plus Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. Preferably take it before just bedtime. In some cases, you may experience vomiting, weight loss, loss of appetite, dryness in the mouth, dizziness, nausea, diarrhoea, and headache. Most of these side effects of Donect M Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Donect M Plus Tablet may cause dizziness and sleepiness. So, do not drive a car or operate any machinery that requires mental focus until you know how this medicine affects you. Increase the intake of fluids to keep yourself hydrated while taking Donect M Plus Tablet as it may cause diarrhoea. Before using Donect M Plus Tablet , inform your doctor if you have ever had heart problems, stomach ulcers, epilepsy, or asthma. 

Uses of Donect M Plus Tablet

Alzheimer’s disease (memory loss)

Medicinal Benefits Mweb

Medicinal Benefits

Donect M Plus Tablet is a combination medication containing Donepezil and Memantine, which treat Alzheimer’s disease. It helps to slow down the progression of moderate to severe Alzheimer's by improving memory and thinking. It also increases the levels of a chemical messenger involved in the transmission of nerve signals. Donepezil is a cholinesterase inhibitor that works by improving the function of nerve cells in the brain by preventing the breakdown of the chemical acetylcholine. Memantine works by lowering the level of chemicals in the brain, which is responsible for causing symptoms of Alzheimer's disease. Together, they balance the levels of chemical messengers in the brain and help transmit nerve signals.

Directions for Use

Swallow Donect M Plus Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Side Effects of Donect M Plus Tablet

  • Vomiting
  • Loss of appetite
  • Dryness in the mouth
  • Dizziness
  • Weight loss
  • Nausea
  • Diarrhoea
  • Headache

Drug Warnings

Do not take Donect M Plus Tablet if you are allergic to Donect M Plus Tablet or any of its ingredients. Donect M Plus Tablet may cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. Increase the intake of fluids to keep yourself hydrated while taking Donect M Plus Tablet as it may cause diarrhoea. Before using Donect M Plus Tablet , inform your doctor if you have ever had heart problems, stomach ulcers, epilepsy, or asthma. Take Donect M Plus Tablet preferably just before bedtime.

Drug-Drug Interactions

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DonepezilIomeprol
Severe
DonepezilBupropion
Severe

Drug-Drug Interactions

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DonepezilIomeprol
Severe
How does the drug interact with Donect M Plus Tablet:
Co-administration of Iomeprol and Donect M Plus Tablet can increase the risk of developing seizures. The risk increases in patients with a history of seizure or head injury.

How to manage the interaction:
Co-administration of Donect M Plus Tablet with Iomeprol can possibly result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor if you experience any symptoms like shortness of breath, irregular heart rhythms, or problems with movement and memory. Do not discontinue any medications without first consulting your doctor.
DonepezilBupropion
Severe
How does the drug interact with Donect M Plus Tablet:
Taking bupropion with Donect M Plus Tablet may increase the levels of Donect M Plus Tablet and the risk of developing seizures.

How to manage the interaction:
Co-administration of bupropion along with Donect M Plus Tablet can lead to an interaction, but it can be taken when recommended by a doctor. However, if you experience sudden dizziness, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DonepezilIohexol
Severe
How does the drug interact with Donect M Plus Tablet:
Coadministration of Iohexol and Donect M Plus Tablet can increase the risk of developing seizures. The risk increases in patients with a history of seizure or head injury.

How to manage the interaction:
Although taking Donect M Plus Tablet and Iohexol together can cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.
DonepezilMetrizamide
Severe
How does the drug interact with Donect M Plus Tablet:
The combined use of metrizamide and Donect M Plus Tablet can increase the risk of developing seizures. If you have a history of seizures or a head injury, contact your doctor immediately.

How to manage the interaction:
Although there is a possible interaction between Donect M Plus Tablet and Metrizamide, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
DonepezilCyclopentolate
Severe
How does the drug interact with Donect M Plus Tablet:
Coadministration of Cyclopentolate with Donect M Plus Tablet can reduce the levels and effects of Cyclopentolate.

How to manage the interaction:
There may be a possibility of interaction between Cyclopentolate and Donect M Plus Tablet, but it can be taken when prescribed by a doctor. However, if you experience any symptoms like sudden dizziness, shortness of breath, or rapid heartbeat consult your doctor immediately. Do not stop using any medications without talking to your doctor.
DonepezilIopamidol
Severe
How does the drug interact with Donect M Plus Tablet:
The combined use of iopamidol and Donect M Plus Tablet can increase the risk of developing seizures. The risk increases in patients with a history of seizures or head injury.

How to manage the interaction:
Taking Donect M Plus Tablet with Iopamidol together can possibly result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor if you experience any symptoms like shortness of breath, irregular heart rhythms, or problems with movement and memory. Do not stop using any medications without a doctor's advice.
DonepezilTramadol
Severe
How does the drug interact with Donect M Plus Tablet:
Coadministration of Donect M Plus Tablet with tramadol can increase the risk of developing seizures. The risk increases in patients with a history of seizure or head injury.

How to manage the interaction:
Taking Donect M Plus Tablet with tramadol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, increased heart rate, blurred vision, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • DONEPEZIL
  • AMANTADINE
  • KETOCONAZOLE
  • PHENYTOIN
  • CARBAMAZEPINE
  • DEXAMETHASONE
  • PHENOBARBITAL
  • CIMETIDINE
  • RANITIDINE
  • BROMOCRIPTINE

Habit Forming

No

Special Advise

  • Donect M Plus Tablet causes drowsiness. Avoid doing activities that require your complete focus and attention like driving when on this drug.
  • Avoid consuming alcohol while on this medication as it can lead to dangerous side effects.
  • The safety and efficacy are not established in pregnant or breastfeeding. Discuss with your doctor in such situations about changing/replacing the medicine with safer alternatives.
  • Do not self-medicate.

Diet & Lifestyle Advise

  • Find the humour in your daily life. Try to watch light-hearted shows to help relieve stress.
  • You can try increasing your mindfulness, by including yoga, meditation, mindfulness-based cognitive therapy, and mindfulness-based stress reduction.
  • Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve diarrhoea.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
  • Reduce your alcohol, caffeine, added sugar, high salt, and high fat intake. 
  • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea, and lemon balm.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of memory loss.

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