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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

DIDANOSINE-400MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[ANTIRETROVIRAL AGENTS]

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - DIN0013

FAQs

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

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Pregnancy

Consult your doctor

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Breast Feeding

Consult your doctor

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Driving

Safe if prescribed

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Liver

Consult your doctor

Dinex EC 400mg Tablet should be used with caution in patients with liver impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your child's condition.

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Kidney

Consult your doctor

Dinex EC 400mg Tablet should be used with caution in children with kidney impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your child's condition.

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Children

Safe if prescribed

Dinex EC 400mg Tablet should be given as prescribed by the paediatrician. The dose of the medicine will be decided by your child's doctor based on the type of the condition.

About Dinex EC 400mg Tablet

Dinex EC 400mg Tablet is an antiretroviral medicine used to treat HIV infection in children. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Virus (AIDS). Symptoms of HIV include fever, chills, night sweats, muscle aches, etc.

Dinex EC 400mg Tablet contains Didanosine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection.

Dinex EC 400mg Tablet may cause certain side effects in your children, such as nausea, headache, stomach pain, loss of appetite, vomiting, depression, fever, tiredness, back pain, blood in urine, diarrhea, muscle pain, dizziness, and allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your paediatrician. Dinex EC 400mg Tablet should be taken as advised by your child's doctor. The doctor will decide the dose of the medicine based on your child's health condition. Do not take more than the recommended dose.

Dinex EC 400mg Tablet should be avoided if your child is allergic to it. It is advised not to take this medicine along with zidovudine, Lamivudine, antacids, etc., as it can cause serious side effects. Hence, avoid giving Dinex EC 400mg Tablet along with these medicines. Inform your doctor if your child has any cardiovascular conditions, liver/kidney disease, pancreatitis, lactic Acidosis, peripheral nephropathy, and optic neuritis on priority. Dinex EC 400mg Tablet is used to treat the infection but does not cure or prevent it. This medicine is used in combination for the treatment of HIV infection.

Uses of Dinex EC 400mg Tablet

HIV Infection

Medicinal Benefits Mweb

Key Benefits

Dinex EC 400mg Tablet contains Didanosine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection. Dinex EC 400mg Tablet is used in combination with other antiretroviral medicines to help reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

Directions for Use

Powder for oral solution: Use Dinex EC 400mg Tablet as advised by your doctor. It should be given at least 30 minutes before or 2 hours after food. Before administration, it should be reconstituted by the pharmacist. Follow all the instructions provided on the label for complete information. Your paediatrician or the pharmacist will explain to you how to give Dinex EC 400mg Tablet to your child.

Side Effects of Dinex EC 400mg Tablet

  • Nausea
  • Abdominal pain
  • Vomiting
  • Dizziness
  • Back pain
  • Blood in urine
  • Loss of appetite
  • Tiredness
  • Depression

Drug Warnings

Dinex EC 400mg Tablet should be avoided if your child is allergic to it. It is advised not to take this medicine along with zidovudine, Lamivudine, antacids, etc., as it can cause serious side effects. Hence, avoid giving Dinex EC 400mg Tablet along with these medicines. Inform your doctor if your child has any cardiovascular conditions, liver/kidney disease, pancreatitis, lactic Acidosis, peripheral nephropathy, and optic neuritis on priority. Dinex EC 400mg Tablet is used to treat the infection but does not cure or prevent it. This medicine is used in combination for the treatment of HIV infection.

Drug-Drug Interactions Checker List

  • CISAPRIDE
  • CYCLOSPORIN
  • MOXIFLOXACIN
  • OFLOXACIN
  • MAGNESIUM HYDROXIDE

Habit Forming

No

Special Advise

  • Get an HIV test done for your child at least every three months.
  • Regular kidney and liver function and bone mineral density tests while taking Dinex EC 400mg Tablet are advised. 

Diet & Lifestyle Advise

  • Try to make your child eat vitamin and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
  • Give low-fat foods to your child, and avoid spicy or oily foods if you notice nausea or vomiting in the child.
  • Avoid using needles, other injection or drug equipment.
  • Make your child drink more fluids and avoid alcoholic beverages to prevent dehydration.  

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