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Prescription drug
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS

Manufacturer/Marketer :

Prisure Medicare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

GASTROINTESTINAL AGENTS

Country of origin

India

Manufacturer/Marketer address

208/b, prime trade centre sativali road, waliv phata, vasai - east, palghar - 401208
Other Info - DEX0409

Author Details

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Dexlet-D Capsule . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Dexlet-D Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

Dexlet-D Capsule may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Dexlet-D Capsule should not be given to children as the safety and effectiveness were not established.

About Dexlet-D Capsule

Dexlet-D Capsule belongs to a group of medicines called gastrointestinal agents used to treat acidity, heartburn, gastro-oesophageal reflux disease (GERD), Zollinger-Ellison syndrome, nausea, vomiting, dyspepsia (indigestion), and peptic ulcers. The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to acidity-related problems.

Dexlet-D Capsule is a combination of two drugs, namely: Dexrabeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Dexrabeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscle. Together, Dexlet-D Capsule helps in treating acidity related problems.

You are advised to take Dexlet-D Capsule for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor if you have a history of gastrointestinal bleeding or intestinal obstruction. Consult your doctor before taking Dexlet-D Capsule if you are pregnant or breastfeeding. Dexlet-D Capsule may cause dizziness, so drive only if you are alert. Dexlet-D Capsule is not recommended for children as safety has not been established. Avoid consuming alcohol with Dexlet-D Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Dexlet-D Capsule

Acidity-related problems

Medicinal Benefits Mweb

Medicinal Benefits

Dexlet-D Capsule is a combination of two drugs, namely: Dexrabeprazole and Domperidone. Dexlet-D Capsule is used to treat acidity, heartburn, gastro-oesophageal reflux disease (GERD), Zollinger-Ellison syndrome, nausea, vomiting, dyspepsia (indigestion), epigastric pain, and peptic ulcers. Dexrabeprazole is a proton pump inhibitor that works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone is a dopamine antagonist which works by increasing the movements and contractions of stomach muscles. Together, Dexlet-D Capsule helps in treating acidity-related problems. 

Directions for Use

Take Dexlet-D Capsule 1hour prior to food. Swallow Dexlet-D Capsule as a whole with a glass of water; do not chew or crush it.

Side Effects of Dexlet-D Capsule

  • Dry mouth
  • Stomach pain
  • Diarrhoea
  • Headache
  • Flatulence

Drug Warnings

Do not take Dexlet-D Capsule if you are allergic to any of its components. Inform your doctor if you have severe kidney, heart or liver disease, or if you are due to have Chromogranin A blood test; if you have fungal infections, heart problems, HIV infection, blockage in intestines, pituitary gland tumour, low levels of potassium or magnesium in the blood. Talk to your doctor if you experience weight loss, problems with swallowing, stomach pain, indigestion, vomit food or blood, or if you pass black stools while taking Dexlet-D Capsule . Consult your doctor if you are pregnant or breastfeeding. Dexlet-D Capsule may cause dizziness, so drive only if you are alert.

Drug-Drug Interactions

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DomperidoneBepridil
Severe

Drug-Drug Interactions

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DomperidoneBepridil
Severe
How does the drug interact with Dexlet-D Capsule:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Dexlet-D Capsule and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dexlet-D Capsule:
Combining Mizolastine with Dexlet-D Capsule can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Dexlet-D Capsule and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dexlet-D Capsule:
Coadministration of Dexlet-D Capsule with Cisapride can increase the blood levels of Dexlet-D Capsule.

How to manage the interaction:
There may be a possibility of interaction between Dexlet-D Capsule and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Dexlet-D Capsule:
Coadministration of Dexlet-D Capsule with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Dexlet-D Capsule and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Dexlet-D Capsule:
Coadministration of Dexlet-D Capsule with Nefazodone can increase the blood levels of Dexlet-D Capsule.

How to manage the interaction:
There may be a possibility of interaction between Dexlet-D Capsule and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneToremifene
Severe
How does the drug interact with Dexlet-D Capsule:
Coadministration of Dexlet-D Capsule with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Dexlet-D Capsule and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dexlet-D Capsule:
Coadministration of Dexlet-D Capsule with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Dexlet-D Capsule and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dexlet-D Capsule:
Coadministration of Dexlet-D Capsule with Ritonavir can increase the blood levels of Dexlet-D Capsule.

How to manage the interaction:
There may be a possibility of interaction between Dexlet-D Capsule and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dexlet-D Capsule:
Coadministration of Dexlet-D Capsule with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Dexlet-D Capsule and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Dexlet-D Capsule:
Coadministration of Dexlet-D Capsule with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Dexlet-D Capsule and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • WARFARIN
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • AMPICILLIN
  • KETOCONAZOLE
  • FLUCONAZOLE
  • VORICONAZOLE
  • DIGOXIN
  • CITALOPRAM
  • ESCITALOPRAM

Habit Forming

No

Special Advise

  • Inform your doctor if you are due to have Chromogranin A blood test.
  • On long-term treatment, Dexlet-D Capsule may cause low magnesium levels, vitamin B12 levels and increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition.

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

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