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  1. Home
  2. Medicine

  3. Depishine-TX Tablet 10's

Prescription drug
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Composition :

PINE BARK EXTRACT-50MG + TRANEXAMIC ACID-250MG

Manufacturer/Marketer :

Livia Healthcare Llp

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIHEMORRHAGIC AGENTS

Country of origin

India

Manufacturer/Marketer address

Level 17, Dlh Park, Ramlal Compound, Swami Vivekananda Rd, Goregaon West, Mumbai, Maharashtra 400064
Other Info - DEP0228

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 8, 2025 | 9:41 AM IST

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Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

No interaction was found. However, it is best to avoid alcohol while taking medication as a precautionary measure.

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Pregnancy

Caution

There are no adequate and well-controlled pregnancy studies. Your doctor will only prescribe if the benefits outweigh the risks.

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Breast Feeding

Caution

Tranexamic acid may be present in trace concentrations in breast milk. However, please consult a doctor if you are a breastfeeding mother.

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Driving

Caution

Depishine-TX Tablet will not impair your ability to drive or operate machines. However, do not drive if you experience any symptoms that affect your ability to concentrate and react.

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Liver

Safe if prescribed

Depishine-TX Tablet is probably safe in patients with liver diseases. Consult your doctor for further advice if you have any concerns about this.

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Kidney

Caution

Depishine-TX Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Limited information is available for the use of Depishine-TX Tablet in pediatric patients. Your doctor will prescribe only if the benefits outweigh the risks.

Product Substitutes

Reference

  1. https://www.eurekalert.org/news-releases/864232
  2. https://www.nhs.uk/medicines/tranexamic-acid/

About Depishine-TX Tablet

Depishine-TX Tablet belongs to the class of medications called ‘Anti-hemorrhagic agents’ used to control bleeding, especially for menorrhagia and nose bleeds. Menorrhagia is a medical condition where menstrual bleeding lasts longer than seven days. It could be intense bleeding. The loss of blood that occurs from the tissue that lines the inside of your nose is known as a nosebleed.

Depishine-TX Tablet is a combination of two medicines: tranexamic acid and pine bark extract. Tranexamic acid is an anti-fibrinolytic medication. It aids in the prevention of fibrinolysis by preventing the breakdown of fibrin. Pine bark extract has essential anti-inflammatory and anti-thrombotic properties that may benefit patients with hemorrhoids, both acute and chronic treatment. Thereby Depishine-TX Tablet treats heavy bleeding.

You should use this medicine as prescribed by your doctor. Most people do not have any side effects while taking Depishine-TX Tablet . However, in few cases, it may cause side effects such as nausea (feeling sick), diarrhoea, and itchy red skin. The majority of these side effects do not necessitate medical treatment and will subside gradually over time. However, if you regularly have these adverse effects, you should seek medical attention.

Depishine-TX Tablet is not suitable for some people. To ensure that Depishine-TX Tablet is safe for you, tell your doctor if you have ever had an allergic reaction to tranexamic acid, pine bark extract, or any other medicine, if you have a history of kidney problems, DVT (deep vein thrombosis) or pulmonary embolism (blocked blood vessel in your lungs), coagulopathy (a rare condition where lots of small blood clots form in your blood followed by abnormal bleeding), epilepsy, irregular periods, and visual disturbances. Also, inform your doctor if you are pregnant or breastfeeding.

Uses of Depishine-TX Tablet

Menorrhagia and Nose bleeding.

Medicinal Benefits Mweb

Medicinal Benefits

Depishine-TX Tablet contains tranexamic acid and pine bark extract. Tranexamic acid is an anti-fibrinolytic medication. It aids in the prevention of fibrinolysis by preventing the breakdown of fibrin. Pine bark extract has essential anti-inflammatory and anti-thrombotic properties that may benefit patients with haemorrhoids, both acute and chronic treatment. Thereby Depishine-TX Tablet treats heavy bleeding.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Depishine-TX Tablet

  • Feeling sick (nausea)
  • Diarrhoea
  • Itchy red skin
  • Stomach upset
  • Headaches

Drug Warnings

Depishine-TX Tablet is not suitable for some people. To ensure that Depishine-TX Tablet is safe for you, tell your doctor if you have ever had an allergic reaction to tranexamic acid, pine bark extract, or any other medicine, if you have a history of kidney problems, DVT (deep vein thrombosis) or pulmonary embolism (blocked blood vessel in your lungs), coagulopathy (a rare condition where lots of small blood clots form in your blood followed by abnormal bleeding), epilepsy, irregular periods, and visual disturbances. And also, inform your doctor if you are pregnant or breastfeeding. 

Drug-Drug Interactions

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Tranexamic acidDrospirenone
Critical
Tranexamic acidLevonorgestrel
Critical

Drug-Drug Interactions

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Tranexamic acidDrospirenone
Critical
How does the drug interact with Depishine-TX Tablet:
Taking drospirenone with Depishine-TX Tablet may increase the risk of blood clot formation.

How to manage the interaction:
Taking Depishine-TX Tablet with Drospirenone is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
Tranexamic acidLevonorgestrel
Critical
How does the drug interact with Depishine-TX Tablet:
Taking Levonorgestrel with Depishine-TX Tablet may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.

How to manage the interaction:
Taking Depishine-TX Tablet with Levonorgestrel may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Tranexamic acidEthinylestradiol
Critical
How does the drug interact with Depishine-TX Tablet:
Taking Ethinylestradiol with Depishine-TX Tablet may increase the risk of blood clot formation.

How to manage the interaction:
Taking Ethinylestradiol with Depishine-TX Tablet is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
Tranexamic acidMedroxyprogesterone
Critical
How does the drug interact with Depishine-TX Tablet:
Taking Medroxyprogesterone acetate with Depishine-TX Tablet may increase the risk of blood clots.

How to manage the interaction:
Taking Medroxyprogesterone with Depishine-TX Tablet is not recommended but can be taken if prescribed by a doctor. Consult your doctor immediately if you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg. Do not stop using any medications without talking to your doctor.
Tranexamic acidEtonogestrel
Critical
How does the drug interact with Depishine-TX Tablet:
Co-administration of Depishine-TX Tablet may cause blood clotting when taken with Etonogestrel.

How to manage the interaction:
Taking Depishine-TX Tablet with Etonogestrel is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
Tranexamic acidNorethisterone
Severe
How does the drug interact with Depishine-TX Tablet:
Using Depishine-TX Tablet together with norethindrone may increase the risk of blood clots.

How to manage the interaction:
Taking norethisterone with Depishine-TX Tablet can lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg, contact a doctor immediately .Do not discontinue any medications without consulting a doctor.
Tranexamic acidCarfilzomib
Severe
How does the drug interact with Depishine-TX Tablet:
Co-administration of Carfilzomib with Depishine-TX Tablet can increase the risk of blood clots.

How to manage the interaction:
Taking carfilzomib with Depishine-TX Tablet is not recommended due to its increased effects, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidEstramustine
Severe
How does the drug interact with Depishine-TX Tablet:
Co-administration of Estramustine with Depishine-TX Tablet can increase the risk of blood clots.

How to manage the interaction:
Taking Estramustine with Depishine-TX Tablet possibly lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tranexamic acidTamoxifen
Severe
How does the drug interact with Depishine-TX Tablet:
Co-administration of tamoxifen with Depishine-TX Tablet can increase the risk of blood clots.

How to manage the interaction:
Although taking tamoxifen and Depishine-TX Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
Tranexamic acidTretinoin
Severe
How does the drug interact with Depishine-TX Tablet:
Co-administration of tretinoin with Depishine-TX Tablet may increase the risk of blood clots.

How to manage the interaction:
Taking tretinoin with Depishine-TX Tablet is not recommended due to its increased effects, however, it can be taken only if your doctor has advised it. If you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Habit Forming

No

Diet & Lifestyle Advise

  • Drink plenty of fluids to stay hydrated. Fluids are necessary to maintain blood flow in your body.
  • Include a diet that includes omega–3 fatty acids, Fiber, and Antioxidants such as flaxseeds, fruits, vegetables, nuts, and beans.
  • Instead of saturated and trans-fats, choose monounsaturated and polyunsaturated fats (fish, nuts, and vegetable oils).
  • Select/prepare foods and beverages with less added sugars/caloric sweeteners.
  • Limit or avoid alcohol consumption.
  • Avoid physical and psychological stress.
  • Replace fatty protein sources with lean alternatives and consume modest quantities of healthy fat sources for improved wellbeing.

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