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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

DECITABINE-50MG

Manufacturer/Marketer :

Aureate Healthcare

Consume Type :

Parenteral

Return Policy :

Not Returnable

Therapeutic Class

[MISCELLANEOUS, CHEMOTHERAPY]

Country of origin

India
Other Info - DECI308

FAQs

Disclaimer

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Alcohol

Safe if prescribed

You are recommended to avoid alcohol consumption while on treatment with Decitafect 50mg Injection as it might cause increased dizziness.

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Pregnancy

Consult your doctor

Decitafect 50mg Injection should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Consult your doctor

Decitafect 50mg Injection should not be used in breastfeeding. Discuss with your doctor if you have any concerns.

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Driving

Safe if prescribed

Decitafect 50mg Injection may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Consult your doctor

Inform your doctor before receiving the Decitafect 50mg Injection if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Consult your doctor

Inform your doctor before receiving the Decitafect 50mg Injection if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Decitafect 50mg Injection is not recommended for children below 18 years as the safety and effectiveness have not been established.

About Decitafect 50mg Injection

Decitafect 50mg Injection belongs to the group of medicines called hypomethylation agents used to treat myelodysplastic syndrome. A myelodysplastic syndrome is a group of malignancies known as myelodysplastic syndromes that occur when immature blood cells in the bone marrow do not mature or turn into healthy blood cells.

Decitafect 50mg Injection contains ‘Decitabine’, which works by helping the bone marrow produce normal blood cells and kills abnormal cells in the bone marrow.

Decitabine should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer chemotherapeutic agents. Decitabine should usually be given for at least four cycles but may be continued if your doctor decides you will benefit from additional treatment. The most common adverse reactions of Decitafect 50mg Injection are injection site reactions, excessive tiredness, headache, dizziness, confusion, fast heartbeat, difficulty falling asleep or staying asleep, weakness, shortness of breath, nausea, constipation, diarrhoea, vomiting, heartburn, chest discomfort and swelling of the hands, feet, ankles, lower legs, or stomach. Talk with your doctor if you experience any of these side effects persistently.

Decitabine may harm your fetus. Avoid taking Decitafect 50mg Injection if you are pregnant or breastfeeding. You or your partner should not become pregnant while you are using decitabine. It would be best if you used birth control to prevent pregnancy in yourself or your partner during your treatment with decitabine and for two months afterwards. Call your doctor if you or your partner becomes pregnant while using decitabine. If you are breastfeeding. Do not breastfeed while you take this drug and for two weeks after your last dose. Decitafect 50mg Injection may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if alert. Decitafect 50mg Injection is not recommended for children below 18 years as safety and effectiveness have not been established. Inform your doctor about your health condition and medications before taking Decitafect 50mg Injection to rule out interactions.

Uses of Decitafect 50mg Injection

Myelodysplastic syndrome

Medicinal Benefits Mweb

Key Benefits

Decitafect 50mg Injection belongs to the group of medicines called hypomethylation agents used to treat myelodysplastic syndrome. Decitafect 50mg Injection contains ‘Decitabine’, which works by helping the bone marrow produce normal blood cells and kills abnormal cells in the bone marrow. On the other hand, it can treat blood cancer, known as acute myeloid leukemia (AML).

Directions for Use

Decitafect 50mg Injection should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents; do not self-administer.

Side Effects of Decitafect 50mg Injection

Drug Warnings

Before taking the Decitafect 50mg Injection, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Before and during your therapy, your doctor will prescribe laboratory testing on a regular basis. You may have a higher risk of infection. Hands must be washed frequently. Avoid contact with those who have illnesses, colds, or the flu. You may bleed more easily. Take precautions to avoid injury. Do not skip any scheduled dose or take other medications unless prescribed by the doctor.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Decitafect 50mg Injection:
Combining Decitafect 50mg Injection with Leflunomide can increase the risk of negative side effects.

How to manage the interaction:
Taking Leflunomide with Decitafect 50mg Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact your doctor right away: infection, complications, fever, chills, diarrhea, sore throat, muscle aches, trouble breathing, losing weight, or pain/burning when you pee. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

Habit Forming

No

Special Advise

  • Regular blood tests are advised before and during treatment with Decitafect 50mg Injection.

Diet & Lifestyle Advise

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