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Combither Syrup 60 ml
About Combither Syrup 60 ml
Combither Syrup 60 ml belongs to the class of 'anti-malarial drugs', primarily used to treat and prevent malaria. Malaria is a disease caused by a plasmodium parasite, transmitted by the bite of infected Anopheles mosquitoes. When an infected mosquito bites a healthy person, it transmits the 'Plasmodium parasite' into the bloodstream, which affects the red blood cells and liver cells. Malaria symptoms usually start in 10 days to 4 weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma and bloody stools.
Combither Syrup 60 ml contains two medicines, namely: Artemether and Lumefantrine. These are anti-malarial drugs that interfere with Plasmodium parasite's growth in the red blood cells of the human body. Combither Syrup 60 ml is a combination that is used to treat non-severe malaria caused by a parasite called 'Plasmodium falciparum,' other Plasmodium species. It works by inhibiting nucleic acid and protein synthesis in Plasmodium falciparum. Artemether is known to reduce parasite biomass and Lumefantrine eliminates residual parasites.
Your doctor will decide the dose and duration based on your medical condition. Common side effects of Combither Syrup 60 ml include headache, dizziness, loss of appetite, weakness, fever, chills, tiredness, muscle/joint pain, nausea, vomiting, abdominal pain, cough and trouble sleeping. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
Before using Combither Syrup 60 ml, inform your doctor if you recently used any prescription and non-prescription medications, including other anti-malarial or antibiotic drugs. Let your doctor know if you are allergic to Combither Syrup 60 ml or its components. Inform your doctor if you have any liver or kidney problems, severe heart diseases and electrolyte imbalance. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. Avoiding alcohol is recommended to rule out any possibility of side effects.
Uses of Combither Syrup 60 ml
Medicinal Benefits
Combither Syrup 60 ml contains two anti-malarial drugs, namely: Artemether and Lumefantrine. It is a combination that treats non-severe malaria caused by a parasite called 'Plasmodium falciparum', other Plasmodium species. It interferes with the growth of Plasmodium parasites in the red blood cells of the human body. Combither Syrup 60 ml works by inhibiting nucleic acid and protein synthesis in Plasmodium falciparum. Artemether reduces parasite biomass and Lumefantrine eliminates residual parasites.
Directions for Use
Storage
Side Effects of Combither Syrup 60 ml
Drug Warnings
Let your doctor know if you use any antibiotic drugs or have recently undergone treatment with other anti-malarial drugs. Brief your medical history to the doctor if you have any liver or kidney problems, malarial infection of the brain, lungs or kidneys, severe heart diseases and electrolyte imbalance. It is essential to inform your doctor if you have hypokalemia (low potassium levels) or hypomagnesemia (low magnesium levels) before starting Combither Syrup 60 ml. Combither Syrup 60 ml may affect QT prolongation that can cause serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have any heart-related problems like heart failure, slow heartbeat, QT prolongation in EKG or ECG (electrocardiogram), and a family history of heart diseases. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother before starting Combither Syrup 60 ml. Avoiding alcohol is recommended to rule out any possibility of side effects like dizziness or drowsiness.
Drug Interactions
Drug-Drug Interaction: Combither Syrup 60 ml may interact with other anti-malarial drugs (mefloquine, quinine, quinidine), drugs treating abnormal heart rhythms (flecainide, amiodarone, sotalol, procainamide, disopyramide), antipsychotics (pimozide, ziprasidone), macrolide antibiotics (erythromycin), antibiotics (ciprofloxacin, moxifloxacin, rifabutin, rifampin), fits medicines (carbamazepine, phenobarbital, phenytoin), antifungals (ketoconazole, itraconazole), HIV drugs (delavirdine, efavirenz, nelfinavir, ritonavir), antidepressants (clomipramine, amitriptyline, imipramine), blood pressure drugs (metoprolol), depression medicines (St. John's wort) and birth control pills.
Drug-Food Interaction: Avoiding alcohol may improve the side effects of Combither Syrup 60 ml. Grapefruit juice may affect the efficacy of Combither Syrup 60 ml; hence please avoid it during treatment with Combither Syrup 60 ml.
Drug-Disease Interaction: Before using Combither Syrup 60 ml, let your doctor know if have any heart diseases, liver or kidney problems, malarial infection of the brain, lungs or kidneys, severe heart diseases, and electrolyte imbalance.
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Disease/Condition Glossary
Malaria: It is a life-threatening disease caused by parasites that enter the body through a mosquito's bite. This is a common disease in countries like Africa, South America and Southern Asia. This disease usually occurs when an Anopheles mosquito (infected with parasite 'Plasmodium') bites a healthy individual and transfers the parasite into the bloodstream. Parasites that cause malaria include Plasmodium vivax, P. ovale, P. malaria and P. falciparum. Malaria symptoms usually start in 10 days to 4 weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma and bloody stools.