apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
Insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Cobaleo AM-P Tablet 10's

Not for online sale
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Composition :

AMITRIPTYLINE-10MG + PREGABALIN-75MG

Manufacturer/Marketer :

Win Life Science Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTICONVULSANT

Country of origin

India

Manufacturer/Marketer address

Gf- 1, Jay Yogeshwar Soc, Navjivan Ajwa Road, Vadodara, Gujarat, 390025, India
Other Info - COB0285

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:33 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
bannner image

Alcohol

Unsafe

Avoid consumption of alcohol while taking Cobaleo AM-P Tablet as it may increase drowsiness and sleepiness.

bannner image

Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Consult your doctor before taking Cobaleo AM-P Tablet ; your doctor will decide whether Cobaleo AM-P Tablet can be taken by breastfeeding mothers or not.

bannner image

Driving

Unsafe

Cobaleo AM-P Tablet may cause drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Caution

Cobaleo AM-P Tablet should not be given to children as the safety and efficacy have not been established.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.7057.pdf
  2. https://www.medicines.org.uk/emc/files/pil.5698.pdf
  3. https://www.drugs.com/amitriptyline.html
  4. https://www.drugs.com/mtm/pregabalin.html

About Cobaleo AM-P Tablet

Cobaleo AM-P Tablet is a combination medicine indicated for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation.

Cobaleo AM-P Tablet is a combination of two drugs: Pregabalin (anti-convulsant), and Amitriptyline (antidepressant). Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Cobaleo AM-P Tablet helps to treat neuropathic pain. 

You are advised to take Cobaleo AM-P Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as weight gain, dry mouth, blurred vision, dizziness, tiredness, nausea, vomiting, diarrhoea, and constipation. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Cobaleo AM-P Tablet may cause drowsiness and dizziness, so drive only if you are alert. Cobaleo AM-P Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Cobaleo AM-P Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Cobaleo AM-P Tablet

Neuropathic pain

Medicinal Benefits Mweb

Medicinal Benefits

Cobaleo AM-P Tablet is a combination of two drugs: Pregabalin (anti-convulsant), and Amitriptyline (antidepressant). Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Cobaleo AM-P Tablet helps to treat neuropathic pain. 

Directions for Use

Take Cobaleo AM-P Tablet with or without food. Swallow Cobaleo AM-P Tablet as a whole with a glass of water; do not chew or break it.

Side Effects of Cobaleo AM-P Tablet

  • Weight gain
  • Dry mouth
  • Blurred vision
  • Dizziness
  • Tiredness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation

Drug Warnings

Do not take Cobaleo AM-P Tablet if you are allergic to any of its contents; if you have taken MAO inhibitors in the last 14days. Inform your doctor before taking Cobaleo AM-P Tablet if you have/had heart problems, bipolar syndrome, severe liver disease or porphyria. Consult your doctor if you are pregnant or breastfeeding. Cobaleo AM-P Tablet may cause drowsiness and dizziness, so drive only if you are alert. Cobaleo AM-P Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Cobaleo AM-P Tablet as it could lead to increased drowsiness and sleepiness.

Drug-Drug Interactions

verifiedApollotooltip
AmitriptylineBepridil
Critical
AmitriptylinePotassium chloride
Critical

Drug-Drug Interactions

Login/Sign Up

AmitriptylineBepridil
Critical
How does the drug interact with Cobaleo AM-P Tablet:
Combining Cobaleo AM-P Tablet and Bepridil may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Cobaleo AM-P Tablet with Bepridil may result in an interaction, it can be used if a doctor recommends it. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylinePotassium chloride
Critical
How does the drug interact with Cobaleo AM-P Tablet:
The combination of Cobaleo AM-P Tablet and Potassium chloride may cause stomach and upper intestinal discomfort. (Only applicable to an oral preparation)

How to manage the interaction:
Although co-administration of Cobaleo AM-P Tablet and Potassium chloride is not recommended as it can possibly lead to an interaction, they can be taken if prescribed by a doctor. If you experience severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (in particular with blood), decreased hunger, and black stools while taking these medications, consult a doctor immediately. Do not discontinue any medications without talking to a doctor.
AmitriptylineGrepafloxacin
Critical
How does the drug interact with Cobaleo AM-P Tablet:
Combining Cobaleo AM-P Tablet and Grepafloxacin may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Cobaleo AM-P Tablet with Grepafloxacin may result in an interaction, it can be used if a doctor recommends it. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor. Note: Grepafloxacin is no longer available in the market. Grepafloxacin should not be combined with any other medications.
AmitriptylineDronedarone
Critical
How does the drug interact with Cobaleo AM-P Tablet:
Combining Cobaleo AM-P Tablet and Dronedarone may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Cobaleo AM-P Tablet with Dronedarone may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
AmitriptylineZiprasidone
Critical
How does the drug interact with Cobaleo AM-P Tablet:
Taking Cobaleo AM-P Tablet and Ziprasidone may increase the risk of irregular heartbeat.

How to manage the interaction:
Although there is a interaction between Cobaleo AM-P Tablet with Ziprasidone, but it can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats . Do not discontinue any medication without consulting a doctor.
AmitriptylineThioridazine
Critical
How does the drug interact with Cobaleo AM-P Tablet:
Cobaleo AM-P Tablet and Thioridazine can enhance each other's effects when used together.

How to manage the interaction:
Although using Cobaleo AM-P Tablet and Thioridazine together can cause an interaction, they can be used if prescribed by a doctor. If you have extreme sleepiness, confusion, anxiety, vomiting, vision problems, feeling hot or cold, sweating, muscle stiffness, fainting, fits, or coma, seek medical help. Do not discontinue any medications without consulting a doctor.
AmitriptylineSparfloxacin
Critical
How does the drug interact with Cobaleo AM-P Tablet:
Combining Cobaleo AM-P Tablet and Sparfloxacin may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Cobaleo AM-P Tablet with Sparfloxacin may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor. Note: Sparfloxacin is no longer available in the market. Grepafloxacin should not be combined with any other medications.
AmitriptylineFurazolidone
Critical
How does the drug interact with Cobaleo AM-P Tablet:
Combining Furazolidone with Cobaleo AM-P Tablet can increase the risk of serotonin syndrome(increased serotonin hormone).

How to manage the interaction:
Although using Furazolidone and Cobaleo AM-P Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Cobaleo AM-P Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylineLinezolid
Critical
How does the drug interact with Cobaleo AM-P Tablet:
Taking Linezolid with Cobaleo AM-P Tablet can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Linezolid and Cobaleo AM-P Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Cobaleo AM-P Tablet. Do not discontinue any medications without consulting a doctor.
AmitriptylinePimozide
Critical
How does the drug interact with Cobaleo AM-P Tablet:
Combining Cobaleo AM-P Tablet and Pimozide may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Cobaleo AM-P Tablet with Pimozide may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

Drug-Drug Interactions Checker List

  • DULOXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • FENTANYL
  • HYDROCODONE
  • ACETAMINOPHEN
  • MORPHINE
  • OXYCODONE
  • TOPIRAMATE
  • ALPRAZOLAM
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • CYCLOBENZAPRINE
  • LEVOTHYROXINE

Habit Forming

No

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, and get plenty of sleep.
  • Try taking a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

All Substitutes & Brand Comparisons

Health Queries

Have a query?