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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Composition :

CLONAZEPAM-0.5MG

Manufacturer/Marketer :

Tas Med India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

NPPA :

Regulated

Therapeutic Class

[ANTICONVULSANT]

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - CLO1492

Author Details

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FAQs

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Alcohol

Safe if prescribed

You are recommended not to consume alcohol along with Clotas MD 0.5 Tablet to avoid unpleasant side-effects like drowsiness, dizziness, or sleepiness.

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Pregnancy

Consult your doctor

Clotas MD 0.5 Tablet belongs to pregnancy Category D. It is usually not recommended during pregnancy. However, consult your doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

Avoid breastfeeding while on treatment with Clotas MD 0.5 Tablet .

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Driving

Safe if prescribed

Clotas MD 0.5 Tablet may cause dizziness, drowsiness and visual disturbances which may affect the ability to drive or operate machinery. So, do not drive or operate heavy machinery if you feel sleepy or dizzy after taking Clotas MD 0.5 Tablet .

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Liver

Consult your doctor

Clotas MD 0.5 Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Consult your doctor

Clotas MD 0.5 Tablet to be taken with caution, especially if you have a history of kidney disorders. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

It is not known whether Clotas MD 0.5 Tablet is safe or effective in treating conditions like panic disorder in children younger than 18 years. So, your doctor will decide whether Clotas MD 0.5 Tablet can be given to children less than 18 years of age or not.

About Clotas MD 0.5 Tablet

Clotas MD 0.5 Tablet belongs to the group of medications called benzodiazepines, primarily used to treat seizures or fits due to epilepsy, panic disorder and involuntary muscle spasms. Clotas MD 0.5 Tablet may also be used to treat restless leg syndrome. Epilepsy is a common neurological disorder that produces recurrent seizures. Seizures occur due to a sudden burst of electrical activity in the brain that disrupts its normal functioning. Panic disorder is an anxiety disorder characterised by frequent episodes of panic or fear.

Clotas MD 0.5 Tablet contains clonazepam, which works by increasing the level of a calming chemical known as gamma-aminobutyric acid (GABA) in the brain. This helps relieve anxiety and seizures (fits). It also helps relax the tense muscles. Thereby, Clotas MD 0.5 Tablet aids in the treatment of seizures, panic disorder, and involuntary muscle spasms.

Your doctor will advise you on how often you need to take this medicine based on your medical condition. In some cases, Clotas MD 0.5 Tablet may cause side effects such as drowsiness, dizziness, fatigue, and problems with memory, walking, and coordination. Most of these side effects do not require medical attention and gradually resolve over time. However, please contact your doctor if the side effects are persistent.

Clotas MD 0.5 Tablet is a habit-forming drug. Therefore, before stopping this medicine, consult your doctor as it may cause withdrawal symptoms like seizures that do not stop, hallucinations (hearing or seeing things that are not there), shaking, and stomach and muscle cramps. If you are pregnant or breastfeeding, consult your doctor before taking Clotas MD 0.5 Tablet . Avoid drinking alcohol while taking Clotas MD 0.5 Tablet as it may cause increased dizziness and drowsiness. It is recommended not to drive or operate any machinery as Clotas MD 0.5 Tablet may cause dizziness, drowsiness, and problems with walking and coordination.

Uses of Clotas MD 0.5 Tablet

Seizures, Panic disorder, Involuntary muscle spasms, Restless leg syndrome

Medicinal Benefits Mweb

Key Benefits

Clotas MD 0.5 Tablet belongs to the group of medications called benzodiazepines, primarily used to treat seizures or fits due to epilepsy, panic disorder and involuntary muscle spasms. Clotas MD 0.5 Tablet may also be used to treat restless leg syndrome. Clotas MD 0.5 Tablet contains clonazepam, which works by increasing the level of a calming chemical known as gamma-aminobutyric acid (GABA) in the brain. It decreases the feeling of nervousness, stress, and anxiety, which leads to a state of calmness and relaxation. Clotas MD 0.5 Tablet benefits people who struggle with anxiety and worries in daily life. Regular intake of the prescribed dose of Clotas MD 0.5 Tablet improves social life and the ability and performance at work, and general wellbeing.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it. Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole. Oral Solution: Shake the bottle well before use. Check the label for directions and take it in dose as prescribed by your doctor with the help of a measuring cup/dropper provided by the pack. Orally disintegrating strip/Orally disintegrating tablet: Keep the strip/tablet in the mouth and allow it to disintegrate. Do not swallow as a whole. Avoid handling the strip/tablet with wet hands.

Side Effects of Clotas MD 0.5 Tablet

Drug Warnings

Do not take Clotas MD 0.5 Tablet if you are allergic to clonazepam or any benzodiazepine class of drugs (diazepam, chlordiazepoxide, bromazepam, or flurazepam). Inform your doctor if you have lung disease, glaucoma, muscle weakness (myasthenia gravis), sleep apnoea (difficulty in sleeping), depression, mood problems, suicidal behaviour/thoughts, liver or kidney problems. Taking Clotas MD 0.5 Tablet with opioid medicines can cause severe drowsiness, breathing problems, coma, and death. Clotas MD 0.5 Tablet should be taken with extreme caution in patients with a history of alcohol or drug abuse. Do not stop taking Clotas MD 0.5 Tablet suddenly as it may cause withdrawal symptoms.

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
ClonazepamMethadone
Severe

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
How does the drug interact with Clotas MD 0.5 Tablet:
Taking Clotas MD 0.5 Tablet with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Clotas MD 0.5 Tablet and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamMethadone
Severe
How does the drug interact with Clotas MD 0.5 Tablet:
Co-administration of Clotas MD 0.5 Tablet with methadone may cause serious side effects like respiratory depression (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Consult the doctor if you are taking Clotas MD 0.5 Tablet with methadone. Until you know how these medicines affect you, avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not discontinue the medication without a doctor's advice.
How does the drug interact with Clotas MD 0.5 Tablet:
Co-administration of Pentazocine with Clotas MD 0.5 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Clotas MD 0.5 Tablet with Pentazocine together can possibly result in an interaction, but it can be taken if a doctor has advised it. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clotas MD 0.5 Tablet:
Co-administration of fentanyl and Clotas MD 0.5 Tablet can increase the risk of side effects.

How to manage the interaction:
Although combining Fentanyl and Clotas MD 0.5 Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you feel sleepiness, loss of balance, or confusion. Do not stop taking any medication without consulting a doctor.
How does the drug interact with Clotas MD 0.5 Tablet:
Co-administration of Clotas MD 0.5 Tablet with Tramadol may significantly lead to adverse effects such as respiratory difficulties (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Clotas MD 0.5 Tablet and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamSufentanil
Severe
How does the drug interact with Clotas MD 0.5 Tablet:
Co-administration of Sufentanil with Clotas MD 0.5 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Clotas MD 0.5 Tablet with Sufentanil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - feeling tired or sleepy, having trouble breathing, or a slower heartbeat - make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Clotas MD 0.5 Tablet:
Using Morphine together with Clotas MD 0.5 Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Morphine with Clotas MD 0.5 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like shortness of breath, feeling tired, having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Clotas MD 0.5 Tablet:
Co-administration of Nalbuphine with Clotas MD 0.5 Tablet can make the side effects worse.

How to manage the interaction:
Although there is a possible interaction between Clotas MD 0.5 Tablet and Nalbuphine, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamEsketamine
Severe
How does the drug interact with Clotas MD 0.5 Tablet:
Co-administration of Clotas MD 0.5 Tablet with Esketamine may increase side effects.

How to manage the interaction:
Although there is a possible interaction, Clotas MD 0.5 Tablet can be taken with Esketamine if prescribed by the doctor. Consult the prescriber if you experience side effects such as confusion, drowsiness, difficulty concentrating, and impairment in judgment, thinking, reaction speed, and motor coordination. Do not discontinue the medication without a doctor's advice.
ClonazepamHydrocodone
Severe
How does the drug interact with Clotas MD 0.5 Tablet:
Co-administration of Clotas MD 0.5 Tablet with Hydrocodone may cause serious side effects like respiratory depression (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Consult the doctor if you are taking Clotas MD 0.5 Tablet with Hydrocodone. Until you know how these medicines affect you, avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CLONAZEPAM-0.5MGGlaucoma
Severe
CLONAZEPAM-0.5MGMental and behavioural disorders due to multiple drug use and use of other psychoactive substances
Severe

Drug-Diseases Interactions

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CLONAZEPAM-0.5MGGlaucoma
Severe
How does the disease interact with Clotas MD 0.5 Tablet:
Benzodiazepines should not be used by people who have open-angle glaucoma or acute angle-closure glaucoma. While these drugs have very rarely being associated with increased intraocular pressure, they do not have anticholinergic effect.

How to manage the interaction:
Clotas MD 0.5 Tablet is contraindicated in patients with acute angle-closure glaucoma or untreated open-angle glaucoma.
CLONAZEPAM-0.5MGMental and behavioural disorders due to multiple drug use and use of other psychoactive substances
Severe
How does the disease interact with Clotas MD 0.5 Tablet:
Benzodiazepines have the potential to cause abuse and dependency. Particularly during extended usage and/or high dosages, tolerance as well as physical and psychological dependency might form.

How to manage the interaction:
Benzodiazepines have the potential to cause dependence and abuse. If dependency is suspected, withdrawal of benzodiazepine therapy should be done by gradual dose reduction.
CLONAZEPAM-0.5MGAbnormalities of breathing
Severe
How does the disease interact with Clotas MD 0.5 Tablet:
When administered in large doses and/or by intravenous administration, benzodiazepines have the potential to cause respiratory depression and apnea. However, some individuals, such as the elderly, the very ill, those who are impaired or taking other CNS depressants, as well as those who have a limited ventilatory reserve, chronic pulmonary insufficiency, or other respiratory diseases, may be susceptible even at regularly prescribed dosages. In these individuals, benzodiazepine therapy should be used with caution.

How to manage the interaction:
When given in high dosages and/or by intravenous administration, benzodiazepines may cause respiratory depression and apnea. Therapy with benzodiazepines should be administered cautiously in patients including elderly, debilitated or severely ill patients, those receiving other CNS depressants, those with limited ventilatory reserve, chronic pulmonary insufficiency or other respiratory disorders.
CLONAZEPAM-0.5MGEpilepsy
Severe
How does the disease interact with Clotas MD 0.5 Tablet:
The use of benzodiazepines for patients with seizure disorders may increase the frequency of generalised tonic-clonic seizures (grand mal) or accelerate the onset of them. The dosage of an appropriate anticonvulsant drug may need to be raised. Particularly after lengthy usage and/or high dosages, abruptly stopping benzodiazepine medication can cause seizures and other withdrawal symptoms. Patients with a history of seizures who discontinue benzodiazepine medication suddenly may experience status epilepticus.

How to manage the interaction:
Benzodiazepines in patients with seizure disorders may increase the incidence of fits. Dose adjustment or appropriate anticonvulsant medication might need to be initiated. Do not discontinue medication without first consulting with the physician.
CLONAZEPAM-0.5MGPoisoning by diuretics and other and unspecified drugs, medicaments and biological substances
Severe
How does the disease interact with Clotas MD 0.5 Tablet:
Benzodiazepines in paediatric and psychiatric patients with aggressive hyperactivity problems. During benzodiazepine medication for such individuals, it is important to keep monitoring out for any indications of paradoxical stimulation.

How to manage the interaction:
Use of benzodiazepines with alcohol is not recommended. Therapy with benzodiazepines should be administered cautiously in patients who might be prone to acute alcohol intake.
CLONAZEPAM-0.5MGDepressive episode
Moderate
How does the disease interact with Clotas MD 0.5 Tablet:
The central nervous system is depressed by benzodiazepines, which can also result in or aggravate mental depression as well as suicidal behaviour and ideas. Patients who were being treated for depression with some of these medications have also reported experiencing episodes of mania and hypomania. In individuals with a history of depression or other mental illnesses, the use of benzodiazepines should be provided with caution. Patients should be watched for any changes in attitude or behaviour. It could be wise to hold off on giving these people a lot of medicine.

How to manage the interaction:
Benzodiazepines may cause or exacerbate mental depression and cause suicidal behavior and ideation. Therapy with benzodiazepines should be administered cautiously in patients with a history of depression or other psychiatric disorders. Monitoring is advised in patients for any changes in mood or behavior.

Drug-Drug Interactions Checker List

Habit Forming

Yes

Special Advise

  • Clotas MD 0.5 Tablet can cause dependance and abuse. Therefore, take Clotas MD 0.5 Tablet only in prescribed doses and as directed by your doctor. Do not self-medicate.
  • Clotas MD 0.5 Tablet may cause suicidal thoughts. Consult your doctor immediately if you notice suicidal behaviour.

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