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  1. Home
  2. Medicine

  3. Clome 50 Tablet 10's

Prescription drug
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy

Composition :

CLOMIFENE CITRATE-50MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

Therapeutic Class

GYNECOLOGY RELATED DRUGS

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - CLO1202

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 8, 2025 | 9:45 AM IST

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Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid alcohol consumption as it may worsen your condition and increase the risk of side effects.

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Pregnancy

Unsafe

Clome 50 Tablet is a category X drug. Clome 50 Tablet is not recommended for pregnant women as it may cause birth defects/congenital disabilities in the unborn baby.

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Breast Feeding

Caution

Clome 50 Tablet decreases the supply of breast milk. So, it should be used with caution in breastfeeding mothers.

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Driving

Caution

Clome 50 Tablet may cause vision problems, so do not drive or operate heavy machinery after taking Clome 50 Tablet unless your vision is normal.

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Liver

Caution

Clome 50 Tablet should be used with extreme caution in patients with liver disease as the liver metabolises Clome 50 Tablet . Dose adjustments may be necessary.

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Kidney

Caution

Please consult your doctor if you have kidney problems before starting Clome 50 Tablet .

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Children

Unsafe

Clome 50 Tablet is not recommended for use in children.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.961.pdf
  2. https://www.drugs.com/clomiphene.html

About Clome 50 Tablet

Clome 50 Tablet belongs to the group of medications called 'ovulation stimulants' used to treat infertility in women who are not ovulating (producing an egg) properly or have irregular or no menstrual cycle. The problem with ovulation is a common cause of infertility in women.

Clome 50 Tablet contains 'Clomifene Citrate' that works by stimulating the production of hormones responsible for the ovulation process.

Take Clome 50 Tablet as prescribed by your doctor. The common side-effects of Clome 50 Tablet are flushing (reddening of the skin, especially the face), headache, tiredness, dizziness, breast pain or tenderness, heavy periods, or bleeding between periods. Tell your doctor if any of these side effects persist or worsen.

Do not take Clome 50 Tablet if you are allergic to any of its ingredients, have liver disease, unexplained and unusual menstrual bleeding, have a type of cancer that gets worse by hormones, or have an ovarian cyst. Clome 50 Tablet is not recommended for pregnant women, children, adolescents, men, and post-menopausal women. Inform your doctor if you are breastfeeding as this medicine may affect the amount of breast milk produced.

Uses of Clome 50 Tablet

Female infertility

Medicinal Benefits Mweb

Medicinal Benefits

Clome 50 Tablet belongs to the group of medications called 'ovulation stimulants' used for fertility enhancement in women experiencing infertility due to problems with ovulation (production and release of an egg from the ovary). It works by stimulating the hormones that are necessary for the ovulation process.

Directions for Use

Swallow Clome 50 Tablet as a whole with water; do not crush, break or chew it.

Side Effects of Clome 50 Tablet

  • Flushing (reddening of the skin, especially the face)
  • Headache
  • Tiredness
  • Dizziness
  • Breast pain or tenderness
  • Heavy periods or bleeding between periods

Drug Warnings

Do not consume Clome 50 Tablet if you are allergic or hypersensitive to Clomifene Citrate or any other ingredients of Clome 50 Tablet . Inform your doctor if you are having an early menopause, diagnosed as infertile, menstrual periods were stopped due to being underweight, previously diagnosed with fits or seizures (fits), uterine fibroids (non-cancerous tumours in the womb), polycystic ovaries (presence of small cysts on the enlarged ovaries), swollen ovaries, or hypertriglyceridemia (increased fat levels in the body) or a family history of hypertriglyceridemia.

Drug-Drug Interactions

verifiedApollotooltip
clomipheneOspemifene
Critical
clomipheneFluoroestradiol (18f)
Severe

Drug-Drug Interactions

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clomipheneOspemifene
Critical
How does the drug interact with Clome 50 Tablet:
Co-administration of Clomifene with Ospemifene can increase the seriousness of side effects.

How to manage the interaction:
Taking Clome 50 Tablet with Ospemifene is not recommended, please consult a doctor before taking it.
clomipheneFluoroestradiol (18f)
Severe
How does the drug interact with Clome 50 Tablet:
Co-administration of Fluoroestradiol F 18 together with Clome 50 Tablet may reduce the action of Fluoroestradiol F 18.

How to manage the interaction:
Taking Clome 50 Tablet with Fluoroestradiol (18f) together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
clomipheneBexarotene
Severe
How does the drug interact with Clome 50 Tablet:
Co-administration of Clome 50 Tablet with Bexarotene may increase the risk of pancreatitis, or inflammation of the pancreas.

How to manage the interaction:
Although there is an interaction, Clome 50 Tablet can be taken with Bexarotene if prescribed by the doctor. Consult the prescriber if you experience symptoms of pancreatitis such as persistent nausea, vomiting, abdominal tenderness, and upper abdominal pain, especially that which is made worse after eating or radiates to the back. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CLOMIFENE CITRATE-50MGOther abnormal uterine and vaginal bleeding
Severe
CLOMIFENE CITRATE-50MGHepatic failure, not elsewhere classified
Severe

Drug-Diseases Interactions

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CLOMIFENE CITRATE-50MGOther abnormal uterine and vaginal bleeding
Severe
How does the disease interact with Clome 50 Tablet:
Abnormal uterine bleeding: In patients who are not diagnosed with abnormal genital bleeding, Clome 50 Tablet is contraindicated. Evaluate the patients for the presence of neoplastic lesions.

How to manage the interaction:
The use of Clome 50 Tablet is contraindicated in patients with undiagnosed, abnormal genital bleeding.
CLOMIFENE CITRATE-50MGHepatic failure, not elsewhere classified
Severe
How does the disease interact with Clome 50 Tablet:
Hepatic dysfunction: Clome 50 Tablet is contraindicated for patients who have liver failure or a past history of hepatic dysfunction. The Clome 50 Tablet is primarily metabolized in the liver and enters into enterohepatic circulation. Thus, there will be increase in serum concentration and half-life of Clome 50 Tablet.

How to manage the interaction:
The use of Clome 50 Tablet is contraindicated in patients with liver disease or history of hepatic dysfunction.
CLOMIFENE CITRATE-50MGDisorders of endocrine glands in diseases classified elsewhere
Severe
How does the disease interact with Clome 50 Tablet:
Pituitary activity: Clome 50 Tablet is contraindicated for patients who have uncontrolled thyroid or adrenal dysfunction, or who have an organic intracranial lesion such as a pituitary tumour. Clome 50 Tablet interacts with oestrogen receptors in several tissues, including the pituitary, causing a rise in pituitary gonadotropin secretion.

How to manage the interaction:
Clome 50 Tablet is contraindicated in patients with uncontrolled thyroid, adrenal dysfunction or pituitary tumour.
CLOMIFENE CITRATE-50MGOther disorders of adrenal gland
Severe
How does the disease interact with Clome 50 Tablet:
Uncontrolled adrenal dysfunction : Clome 50 Tablet is contraindicated in patients with uncontrolled adrenal function. Adrenal dysfunction can make pregnancy difficult. Clome 50 Tablet therapy may cause changes in steroid production and/or fluid balance.

How to manage the interaction:
The use of Clome 50 Tablet is contraindicated in patients with uncontrolled adrenal function.
CLOMIFENE CITRATE-50MGDisorders of lipoprotein metabolism and other lipidaemias
Moderate
How does the disease interact with Clome 50 Tablet:
Hyperlipidemia: Some patients who are on Clome 50 Tablet therapy have reported hypertriglyceridemia. Preexisting hyperlipidemia or a family history of hyperlipidemia, Higher doses of Clome 50 Tablet for a long period are related to an increased risk of hypertriglyceridemia. In this conditions, Monitor plasma triglycerides regular basis and also at base line before initiating the therapy with Clome 50 Tablet.

How to manage the interaction:
Hypertriglyceridemia may occur during Clome 50 Tablet therapy, especially in patients with a family history of hyperlipidemia and use of higher than the recommended dose and/or longer duration of treatment. Periodic monitoring of plasma triglycerides is recommended in patients with preexisting or family history of hyperlipidemia. Pretreatment screening of triglyceride levels is advised in patients initiating Clome 50 Tablet therapy.

Drug-Drug Interactions Checker List

  • BEXAROTENE

Habit Forming

No

Special Advise

Clome 50 Tablet may cause multiple pregnancies (pregnant with more than one child at the same time) or ectopic pregnancy (growing foetus outside the womb). These conditions may also occur if you are not taking this medicine. However, discuss with your doctor the possible risks before taking Clome 50 Tablet .

Diet & Lifestyle Advise

  • Consume a healthy diet rich in fibre and proteins and low in carbohydrates and fats. 
  • Avoid processed or high-sugar foods. 
  • Stay active and shed excess weight if you are overweight or obese. Do not perform intense exercises as they may negatively impact your reproductive health. Increase the intensity of exercise gradually.
  • Being underweight may also reduce your chances of getting pregnant. So, prepare a diet chart that can help you gain weight healthily. 
  • Avoid stress as it may decrease your chances of getting pregnant. Try relaxation techniques and receive support and counselling if necessary. 
  • Limit alcohol and caffeine intake.
  • Quit smoking.

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