Cleft 20 Tablet 10's

Cleft 20 Tablet 10's belongs to the group of medicines called 'anti-rheumatic agents' used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales). 

Cleft 20 Tablet 10's contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling. 

Take Cleft 20 Tablet 10's at the same time every day as prescribed by your doctor. In some cases, Cleft 20 Tablet 10's may cause common side-effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Cleft 20 Tablet 10's if you are pregnant or planning for pregnancy as Cleft 20 Tablet 10's may cause serious congenital disabilities. Cleft 20 Tablet 10's should not be taken by breastfeeding mothers as it passes into breast milk. Cleft 20 Tablet 10's may cause dizziness, so drive with caution. Avoid consuming alcohol along with Cleft 20 Tablet 10's as it could lead to increased dizziness and liver damage. Cleft 20 Tablet 10's may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Cleft 20 Tablet 10's belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Cleft 20 Tablet 10's is a disease-modifying antirheumatic drug (DMARDs) which inhibits an enzyme called dihydroorotate dehydrogenase and has antiproliferative activity (suppresses the cell growth). Thereby, helps in treating inflammation, redness, and swelling.

• Diarrhoea
• Nausea
• Stomach pain
• Indigestion
• Rash
• Hair loss

Do not take Cleft 20 Tablet 10's if you are allergic to leflunomide, have severe liverkidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Cleft 20 Tablet 10's is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Cleft 20 Tablet 10's if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Cleft 20 Tablet 10's may cause dizziness, so drive with caution. Cleft 20 Tablet 10's may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

• IBUPROFEN
• NAPROXEN
• ACETAMINOPHEN
• ASPIRIN
• DULOXETINE
• PREDNISONE
• CELECOXIB
• AZATHIOPRINE
• MELOXICAM
• METHOTREXATE
• ETANERCEPT
• ADALIMUMAB
• ABATACEPT
• INFLIXIMAB
• HYDROXYCHLOROQUINE

Regular blood tests to monitor your liver function after starting Cleft 20 Tablet 10's, and for every 6-8 weeks are advised.

• Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
• Performing yoga may also help in improving joint flexibility and pain management.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Acupuncture, massage and physical therapy may also be helpful.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
• Avoid smoking and alcohol consumption.