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CILANEM INJECTION 1GM

CILANEM INJECTION 1GM

About CILANEM INJECTION 1GM

CILANEM INJECTION 1GM is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach and female reproductive organs. CILANEM INJECTION 1GM may also be used in the management of patients with low white blood cell count who have a fever, which is suspected to be due to bacterial infection. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. CILANEM INJECTION 1GM does not work against infections caused by the virus, including cold and flu. 
 
CILANEM INJECTION 1GM is a combination of two drugs, namely: Cilastatin (dehydropeptidase inhibitor) and Imipenem (antibacterial). Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, CILANEM INJECTION 1GM helps to treat bacterial infections.
 
CILANEM INJECTION 1GM will be administered by a healthcare professional; do not self-administer. In some cases, CILANEM INJECTION 1GM may cause common side effects such as nausea, vomiting, diarrhoea, swelling, and redness at the site of injection. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. CILANEM INJECTION 1GM may cause dizziness, so drive with caution. Avoid alcohol consumption as it might cause increased dizziness and sleepiness. CILANEM INJECTION 1GM should not be given to children below one year or those who weigh below 30kg with kidney problems. CILANEM INJECTION 1GM is not recommended in paediatric patients with CNS infections due to the risk of seizures. Keep your doctor informed about your health condition and medications to rule out any unpleasant side effects.

Uses of CILANEM INJECTION 1GM

Severe bacterial infections

Medicinal Benefits

CILANEM INJECTION 1GM is a combination of two drugs, namely: Cilastatin (dehydropeptidase inhibitor) and Imipenem (antibacterial). CILANEM INJECTION 1GM is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach, and female reproductive organs. CILANEM INJECTION 1GM may also be used in the management of patients with low white blood cell count who have a fever, which is suspected to be due to bacterial infection. Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, CILANEM INJECTION 1GM helps to treat bacterial infections. Imipenem is a broad-spectrum antibiotic that is effective against a wide range of aerobic and anaerobic bacteria.

Directions for Use

CILANEM INJECTION 1GM will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CILANEM INJECTION 1GM

  • Nausea
  • Vomiting
  • Diarrhoea
  • Swelling
  • Redness at the site of injection

Drug Warnings

Do not take CILANEM INJECTION 1GM if you are allergic to any of its components. Inform your doctor if you have an allergy to antibiotics, colitis, gastrointestinal disease, urinary/kidney problems, CNS disorders, seizures/fits, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption as it might cause increased dizziness and sleepiness. CILANEM INJECTION 1GM should not be given to children below one year or those who weigh below 30kg with kidney problems. CILANEM INJECTION 1GM is not recommended in paediatric patients with CNS infections due to the risk of seizures. CILANEM INJECTION 1GM may cause dizziness and sleepiness, so drive with caution.

Drug Interactions

Drug-Drug Interactions: CILANEM INJECTION 1GM may interact with anti-viral (Ganciclovir), uricosurics (Probenecid), anti-epileptic (Valproic acid, Divalproex sodium), blood thinner (warfarin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the lining of the colon), CNS disorders, hemodialysis, kidney or liver dysfunction.

Drug-Drug Interactions Checker List

  • GANCICLOVIR
  • PROBENECID
  • VALPROIC ACID
  • DIVALPROEX SODIUM
  • WARFARIN

Habit Forming

No

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid/limit the consumption of alcohol and usage of tobacco.

Special Advise

  • CILANEM INJECTION 1GM may cause abnormal Coombs, liver, blood, and kidney function tests. Inform the person doing the tests that you are on treatment with CILANEM INJECTION 1GM. 

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Harmful bacteria produce chemicals known as toxins, which can damage tissue and cause sickness. Symptoms of bacterial infection include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicines are more prone to bacterial infection.