CASSOTIDE 50MG TABLET belongs to the class of anticancer drugs called non-steroidal anti-androgens used to treat prostate cancer. Prostate cancer is prostate gland cancer (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems.

CASSOTIDE 50MG TABLET contains Bicalutamide which works by inhibiting the effects of androgens (male hormones) such as testosterone that increase the growth of prostate cancer cells. CASSOTIDE 50MG TABLET prevents testosterone from binding to androgen receptors on the prostate cancer cells and starves cancer cells of testosterone. Thereby, it prevents the growth of prostate cancer cells and eventually shrinks the prostate tumor.

Take CASSOTIDE 50MG TABLET with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience weakness, skin rash, swelling and tenderness of the breast, nausea, dry skin, weight gain, hair loss, hot flushes (sudden feeling of warmth), anemia (lack of blood), reduces sex drive, constipation, depression, indigestion or dizziness. Most of these side effects of CASSOTIDE 50MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to CASSOTIDE 50MG TABLET or any other medicines, please tell your doctor. CASSOTIDE 50MG TABLET is not recommended for women and children. Please consult a doctor if you are pregnant or breastfeeding before taking CASSOTIDE 50MG TABLET. Please consult a doctor if you want to father a child before taking CASSOTIDE 50MG TABLET as it may impair fertility in men. Avoid taking CASSOTIDE 50MG TABLET with cisapride, astemizole, or terfenadine. Avoid direct exposure to excessive UV light or sunlight and wear protective clothing while going out in the sun as CASSOTIDE 50MG TABLET may increase sunburn risk. If you have diabetes, liver, or heart problems, inform your doctor before taking CASSOTIDE 50MG TABLET.

CASSOTIDE 50MG TABLET contains Bicalutamide, an anticancer drug used in the treatment of prostate cancer. CASSOTIDE 50MG TABLET works by inhibiting the effects of androgens (male hormones) such as testosterone that increase the growth of prostate cancer cells. CASSOTIDE 50MG TABLET prevents testosterone from binding to androgen receptors on the prostate cancer cells and starves cancer cells of testosterone. Thereby, it prevents the growth of prostate cancer cells and eventually shrinks the prostate tumor. Also, CASSOTIDE 50MG TABLET relieves difficulty in urination. CASSOTIDE 50MG TABLET can be used in combination with radiation therapy to treat prostate cancer where cancer has spread from the prostate gland to the surrounding tissues.

• Weakness
• Skin rash
• Swelling and tenderness of breast
• Nausea
• Dry skin
• Weight gain
• Hair loss
• Hot flushes (sudden feeling of warmth)
• Anaemia (lack of blood)
• Reduced sex drive
• Constipation
• Depression
• Indigestion
• Dizziness

If you are allergic to CASSOTIDE 50MG TABLET or any other medicines, please tell your doctor. CASSOTIDE 50MG TABLET is not recommended for women and children. Please consult a doctor if you are pregnant or breastfeeding before taking CASSOTIDE 50MG TABLET. You and your partner recommend using effective birth control measures while taking CASSOTIDE 50MG TABLET and for 130 days after discontinuing CASSOTIDE 50MG TABLET. Please consult a doctor if you want to father a child before taking CASSOTIDE 50MG TABLET as it may impair fertility in men. You are advised to quit smoking as it may increase the risk of prostate cancer. Avoid taking CASSOTIDE 50MG TABLET with cisapride, astemizole, or terfenadine. Regular tests are recommended to monitor liver function and if there is any severe disturbance in liver functioning, avoid taking CASSOTIDE 50MG TABLET. Avoid direct exposure to excessive UV light or sunlight and wear protective clothing while going out in the sun as CASSOTIDE 50MG TABLET may increase sunburn risk. If you have diabetes, liver, or heart problems, inform your doctor before taking CASSOTIDE 50MG TABLET.

Drug-Drug Interactions: CASSOTIDE 50MG TABLET may have interaction with medicine for stomach disorders (cisapride), anti-allergic drugs (astemizole, terfenadine), heart-related drugs (procainamide, amiodarone, sotalol, quinidine), antibiotic (moxifloxacin), opioid painkiller (methadone), blood thinner (warfarin), immunosuppressant (ciclosporin), antacid (cimetidine), antifungal (ketoconazole).

Drug-Food Interactions: CASSOTIDE 50MG TABLET may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with CASSOTIDE 50MG TABLET as it may increase concentrations of CASSOTIDE 50MG TABLET and cause more adverse effects.

Drug-Disease Interactions: If you have diabetes, liver or heart problems, inform your doctor before taking CASSOTIDE 50MG TABLET.

• CISAPRIDE
• ASTEMIZOLE
• TERFENADINE
• PROCAINAMIDE
• AMIODARONE
• SOTALOL
• QUINIDINE
• MOXIFLOXACIN
• METHADONE
• WARFARIN
• CICLOSPORIN
• CIMETIDINE
• KETOCONAZOLE

• Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
• Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products as they may increase prostate cancer risk.
• Exercise regularly to lose weight as obesity is also considered as a risk factor for prostate cancer.
• Quit smoking to reduce the risk of prostate cancer.

Regular blood tests are recommended to monitor changes in blood and liver functioning while taking CASSOTIDE 50MG TABLET.

Prostate cancer: It is prostate gland cancer (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems. It is the most common type of cancer in men. The cause of prostate cancer is unknown and may be caused due to exposure to certain chemicals or family history. There are certain factors that increase the risk of prostate cancer, such as a family history of prostate cancer, older age, obesity, or genetic changes.