Big-Nac Sr Tablet 10's

Big-Nac Sr Tablet 10's belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or pain killers used to reduce and relieve pain, and inflammation (swelling) associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Arthritis is a condition which affects the joints. Symptoms include swelling, pain, inflammation, stiffness, and tenderness. 

Big-Nac Sr Tablet 10's contains 'Aceclofenac' which works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

You are advised to take Big-Nac Sr Tablet 10's for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Big-Nac Sr Tablet 10's may cause certain common side-effects such as dizziness, diarrhoea, nausea, and increased liver enzymes in the blood. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Big-Nac Sr Tablet 10's may cause drowsiness and dizziness, so drive with caution. Big-Nac Sr Tablet 10's is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Big-Nac Sr Tablet 10's as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Big-Nac Sr Tablet 10's belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) used to reduce and relieve pain, redness, and inflammation (swelling) in patients suffering from osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Big-Nac Sr Tablet 10's works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins which are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

• Dizziness
• Diarrhoea
• Nausea
• Increased liver enzymes in blood

If you have had any recent heart surgery, do not take Big-Nac Sr Tablet 10's as it can increase the risk of heart attack or stroke. Do not take Big-Nac Sr Tablet 10's if you are allergic to aceclofenac or other NSAIDs (such as ibuprofen, diclofenac or naproxen); if you have stomach ulcers, have suffered bleeding problems, clotting problems, severe heart, liver or kidney problems. Inform your doctor if you have or had disorders of the stomach, blood circulation problems to the brain, asthma, porphyria (blood disorder), diabetes, high blood pressure, auto-immune diseases, connective tissue diseases; if you are recovering from major surgery or if you are elderly. Consult your doctor if you are pregnant or breastfeeding. Big-Nac Sr Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Big-Nac Sr Tablet 10's is not recommended for children as safety has not been established. Avoid consuming alcohol along with Big-Nac Sr Tablet 10's as it could lead to increased drowsiness and may also increase the risk of stomach bleeding. Stop taking Big-Nac Sr Tablet 10's and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach such as blood in stools. Do not take any other NSAIDs for pain relief along with Big-Nac Sr Tablet 10's unless prescribed. 

Drug-Drug Interactions: Big-Nac Sr Tablet 10's may have interaction with pain killers (aspirin, ibuprofen, naproxen, celecoxib, etoricoxib), anti-depressants (citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, lithium), cardiac glycoside (digoxin), anti-hypertensives (enalapril, lisinopril, losartan, candesartan, hydralazine, methyldopa, clonidine, moxonidine, propranolol), antibiotics (ciprofloxacin, ofloxacin, levofloxacin moxifloxacin), diuretics (furosemide, amiloride hydrochloride), blood thinners (warfarin, heparin, clopidogrel), anti-rheumatoid (methotrexate), steroids (mifepristone), glucocorticoids (hydrocortisone, prednisolone), immunosuppressants (ciclosporin, tacrolimus), anti-HIV (zidovudine), anti-diabetic (glibenclamide, gliclazide, tolbutamide).

Drug-Food Interactions: Avoid consumption of alcohol while taking Big-Nac Sr Tablet 10's as it might cause increased dizziness and risk of stomach bleeding.

Drug-Disease Interactions: Inform your doctor if you have stomach ulcers, blood disorders, disorders of the stomach, blood circulation problems to the brain, asthma, porphyria, diabetes, high blood pressure, auto-immune diseases, connective tissue diseases, heart, kidney and liver problems.

• ASPIRIN
• IBUPROFEN
• NAPROXEN
• CELECOXIB
• ETORICOXIB
• CITALOPRAM
• ESCITALOPRAM
• FLUOXETINE
• FLUVOXAMINE
• PAROXETINE
• SERTRALINE
• LITHIUM
• DIGOXIN
• ENALAPRIL
• LISINOPRIL
• LOSARTAN
• HYDRALAZINE
• METHYLDOPA
• CLONIDINE
• PROPRANOLOL
• MOXONIDINE
• CIPROFLOXACIN
• OFLOXACIN
• LEVOFLOXACIN
• MOXIFLOXACIN
• FUROSEMIDE
• WARFARIN
• HEPARIN
• CLOPIDOGREL
• METHOTREXATE
• MIFEPRESTONE
• HYDROCORTISONE
• PREDNISOLONE
• CYCLOSPORINE
• TACROLIMUS
• ZIDOVUDINE
• GLIBENCLAMIDE
• GLICLAZIDE
• CANDESARTAN
• AMILORIDE HYDROCHORIDE
• TOLBUTAMIDE

• Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
• Performing yoga may also help in improving joint flexibility and pain management.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
• Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Acupuncture, massage and physical therapy may also be helpful.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
• Avoid smoking and alcohol consumption.

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation and tenderness. The main reason for osteoarthritis is age, the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include a past injury such as torn cartilage, dislocated joints and ligament injuries. 

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain usually starts in the lower back and can spread to the neck, damaged joints or other parts of the body. Symptoms of ankylosing spondylitis include decreased flexibility which usually leads to hunched-forward posture, pain and back and joints.