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48 Hrs returnable
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Prescription drug

Whats That

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S ADENOSYL L METHIONINE
ADEMETIONINE-400MG
ORAL
Not Returnable
Prescription drug
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Country of origin

India
Other Info - BIB0018

FAQs

Bibtral-400 Tablet 10's contains Ademetionine is used in the treatment of liver disease, depression, and osteoarthritis. It is used in liver conditions associated with reduced bile formation (intrahepatic cholestasis). It restores the balance of serotonin, a natural chemical present in the brain. It also blocks the production of certain inflammatory chemical substances that cause pain and swelling in osteoarthritis.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Do not discontinue Bibtral-400 Tablet 10's without consulting your doctor. To treat your condition effectively, continue taking Bibtral-400 Tablet 10's for as long as advised. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Bibtral-400 Tablet 10's.
Do not take Bibtral-400 Tablet 10's if you have used MAO inhibitors (like isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others) in the last 14 days as the co-administration of Bibtral-400 Tablet 10's and MAO inhibitor cause serious drug interaction. Let know doctor know about this.
No, the Bibtral-400 Tablet 10's does not cure arthritis. Bibtral-400 Tablet 10's is only used to relieve symptoms of arthritis, such as joint pain, swelling and stiffness.

Disclaimer

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Alcohol

Caution

Avoid consumption of alcohol while taking Bibtral-400 Tablet 10's as it may cause increased dizziness and liver damage.

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Pregnancy

Caution

Avoid taking Bibtral-400 Tablet 10's if you are pregnant unless advised by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will recommend only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Bibtral-400 Tablet 10's, your doctor will decide whether Bibtral-400 Tablet 10's can be taken by breastfeeding mothers or not.

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Driving

Caution

Bibtral-400 Tablet 10's does not affect your ability to drive. However, you are advised to be cautious while driving if you experience dizziness.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Bibtral-400 Tablet 10's can be given to children with caution only if recommended by the doctor.

About Bibtral-400 Tablet 10's

Bibtral-400 Tablet 10's belongs to the class of medication called Nutritional supplements used to treat various medical conditions, including depression, reduce pain and swelling in the joints conditions such as osteoarthritis, biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile and biliary and liver diseases caused by cystic fibrosis. It is also used to treat liver disease during pregnancy, improve symptoms in people with fibromyalgia, and treat nerve problems in people with AIDS or sexual dysfunction in men with depression.

Bibtral-400 Tablet 10's contains Ademetionine, a naturally occurring substance found in cells, tissue, and body fluids. It is produced from methionine (amino acid) and is used to treat liver disease, depression, and osteoarthritis. Bibtral-400 Tablet 10's ensures sufficient levels of glutathione in the liver are maintained to minimize liver damage. It also prevents the increase of lipids associated with cirrhosis outside the liver. It also affects certain chemical messengers (serotonin) in the brain, which communicate between brain cells, regulating mood and treating depression. It stimulates the production of parts of cartilage, reduces the inflammatory mediator, and has painkilling properties.

Take Bibtral-400 Tablet 10's as recommended by your doctor. In some cases, you may experience common side-effects such as abdominal discomfort, abdominal pain, diarrhoea, nausea, dizziness, and insomnia. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not discontinue Bibtral-400 Tablet 10's without consulting your doctor. Do not take Bibtral-400 Tablet 10's if you are pregnant or breastfeeding unless advised. Bibtral-400 Tablet 10's can be given to children with extreme caution if recommended by the doctor. Avoid consuming alcohol with Bibtral-400 Tablet 10's as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Bibtral-400 Tablet 10's

Depression, Primary biliary cholangitis, Osteoarthritis

Medicinal Benefits Mweb

Medicinal Benefits

The Bibtral-400 Tablet 10's contains Ademetionine, a naturally occurring substance in cells, tissue, and body fluids. It is produced from methionine (amino acid) and is used to treat liver disease, depression, and osteoarthritis. In liver disease, Bibtral-400 Tablet 10's ensures sufficient glutathione levels in the liver to minimize liver damage. It also prevents the increase of lipids associated with cirrhosis outside the liver. In depression, it affects certain chemical messengers (serotonin) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. In osteoarthritis, It stimulates the production of cartilage parts, reduces the inflammatory mediator, and has painkilling properties. Bibtral-400 Tablet 10's is also effective in treating liver disease during pregnancy, improving symptoms in fibromyalgia, treating nerve problems in people with AIDS, or sexual dysfunction in men with depression.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Bibtral-400 Tablet 10's

  • Headache
  • Dizziness
  • Feeling anxious
  • Vomiting
  • Stomach upset
  • Diarrhoea
  • Constipation
  • Insomnia (sleep problem)
  • Increased sweating

Drug Warnings

Do not take Bibtral-400 Tablet 10's if you are allergic to any of its contents, if you have used an MAO inhibitor in the past 14 days, if the inflammation of gall bladder and bile ducts, narrowing or blockage of bile ducts, biliary colic, calcified gallstones, improper constriction of the gallbladder, gastric or duodenal ulcer. Inform your doctor if you have heart disease, seizure disorders, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, acute alcohol intoxication, glaucoma, thyroid problems, or kidney and liver problems. Do not take Bibtral-400 Tablet 10's if you are pregnant or breastfeeding unless advised by your doctor. Bibtral-400 Tablet 10's can be given to children with caution if recommended by the doctor. Avoid consuming alcohol along with Bibtral-400 Tablet 10's as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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Drug-Food Interactions

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Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • MOCLOBEMIDE
  • PHENELZINE
  • IPRONIAZID
  • ISOCARBOXAZID
  • NIALAMIDE
  • TRANYLCYPROMINE
  • SELEGILINE
  • BUPROPION
  • DULOXETINE
  • FLUOXETINE
  • SERTRALINE
  • LEVODOPA
  • TRAMADOL
  • TRAZODONE
  • HYDROCODONE
  • OXYCODONE
  • ACETAMINOPHEN

Habit Forming

No

Special Advise

  • Your doctor may advise a regular liver function test to monitor the liver's function and the treatment progress.
  • Do not use Bibtral-400 Tablet 10's if you have used an MAO inhibitor (antidepressant) in the past 14 days, as a dangerous drug interaction could occur.

Diet & Lifestyle Advise

Liver disease:

  • Include foods such as bell peppers, citrus fruits, leafy vegetables, tomatoes, milk, fish, low-fat dairy, beans, nuts, lentils, tofu, and tempeh in your diet.
  • Foods rich in vitamins B and C and calcium are good for the gallbladder.
  • Plant-based protein foods such as beans, nuts, lentils, tofu, and tempeh help prevent gallbladder disease.
  • Avoid high-fat, trans-fat, processed foods, white bread, white pasta, and sugars.
  • Avoid tobacco and alcohol consumption.

Depression:

  • Maintaining a healthy diet and regular exercise helps improve overall health and boost self-esteem.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables, and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help properly maintain neurotransmitters. 
  • Avoid smoking and alcohol consumption.

Osteoarthritis:

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.

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