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Written By ,
Reviewed By Sunny S , MBBS
48 Hrs returnable
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ATUBRI 500MG TABLET, Pack of 10 TABLETS
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Whats That

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CAPECITABINE-500MG
Pfizer Ltd
ORAL
Not Returnable
Apr-24
ANTINEOPLASTIC
India
The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051
Other Info - ATU0001

FAQs

ATUBRI 500MG TABLET interferes with the growth of the cancer cells' genetic material (DNA). This slows the growth of cancer cells and eventually kills them.
ATUBRI 500MG TABLET can make your skin more sensitive to the harmful effects of sunlight. Hence it is advised to wear protective clothing while using ATUBRI 500MG TABLET. It is recommended to avoid tanning booths and sunlamps.
Yes, ATUBRI 500MG TABLET may change the results of blood tests and other laboratory tests. Inform the person doing the tests that you are taking ATUBRI 500MG TABLET as regular monitoring of liver and kidney functions tests, electrolyte levels and blood cells is required.
ATUBRI 500MG TABLET might affect fertility (ability to have children) in both men and women. You may not be able to become pregnant or father a child after treatment with ATUBRI 500MG TABLET. However, it is essential to talk to your doctor before starting treatment with ATUBRI 500MG TABLET if you think you may want to have a baby in the future.
Yes, ATUBRI 500MG TABLET commonly affects the hair by making it thin, which further causes hair loss. However, it is not very common. Hair reduction possibly happens due to the estrogen-lowering effect of ATUBRI 500MG TABLET. These effects are not long-lasting and may return after some time. If it matters to you, then consult your doctor for further advice.
ATUBRI 500MG TABLET may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking ATUBRI 500MG TABLET.
Your doctor will decide the number of treatment cycles and the frequency of ATUBRI 500MG TABLET to be taken, depending on the type and stage of the cancer being treated.
No, it is advised not to use these two medicines at the same time as they may cause severe drug reactions. Maintain a gap of at least four weeks between the last dose of brivudine and the first dose of ATUBRI 500MG TABLET.
While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/020896s037lbl.pdf
  2. https://www.medicines.org.uk/emc/files/pil.11498.pdf
  3. https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/capecitabine
  4. https://www.nhs.uk/conditions/cancer/#:~:text=Cancer%20is%20a%20condition%20where,process%20is%20known%20as%20metastasis.

ATUBRI 500MG TABLET belongs to a group of medicines known as 'anti-cancer' used to treat breast, colon and stomach cancer. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Cancer sometimes begins in one body part before spreading to other areas. This process is known as metastasis.

ATUBRI 500MG TABLET contains Capecitabine, an anti-cancer medication that is cytotoxic (causes cell death). When taken, it gets converted into 5-fluorouracil (chemical), which hampers the synthesis of genetic materials (DNA) in the cancer cells, thereby interfering with their growth. As a result, cancer cells' growth is slowed down and eventually killed.

You may experience certain common side-effects such as nausea, vomiting, weakness, loss of appetite, increased risk of infection, hair loss, diarrhoea, decreased blood cells (red cells, white cells, and platelets), mouth ulcers, blisters on fingers/feet in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking ATUBRI 500MG TABLET, inform your doctor if you have any infection because ATUBRI 500MG TABLET may worsen the infection. Some patients may experience increased sensitivity to light while taking ATUBRI 500MG TABLET; avoiding prolonged exposure to sunlight is recommended. Inform your doctor if you are pregnant as ATUBRI 500MG TABLET can cause harmful effects on the unborn baby. Both women and men using ATUBRI 500MG TABLET should use birth control to avoid pregnancy. You should not take ATUBRI 500MG TABLET during breastfeeding. Use ATUBRI 500MG TABLET with caution in elderly patients. If you have had leukaemia (blood cancer) and are in remission, do not take live vaccines for three months after your last chemotherapy. You and your surrounding people, such as family members, should not take the polio vaccine.

Breast cancer, stomach, rectal and colon cancer

Medicinal Benefits Mweb

ATUBRI 500MG TABLET belongs to the group of anti-cancer medicines. It contains Capecitabine which is cytotoxic (causes cell death). It is used to treat cancer of the colon, breast and stomach. When taken, it gets converted into 5-fluorouracil (chemical), which hampers the synthesis of genetic materials (DNA) in the cancer cells, thereby interfering with their growth. As a result, the growth of cancer cells is slowed down, and eventually, they are killed.

Swallow it as a whole with water; do not crush or chew it.

  • Nausea
  • Vomiting
  • Weakness
  • Loss of appetite
  • Increased risk of infection
  • Hair loss
  • Diarrhoea
  • Decreased blood cells 
  • Mouth ulcer
  • Blisters on fingers/feet

Before taking ATUBRI 500MG TABLET, inform your doctor if you have any infection because ATUBRI 500MG TABLET may worsen the infection. If you have any allergy symptoms, talk to your doctor; inform your doctor if you have a metabolic disorder called DPD (dihydropyrimidine dehydrogenase deficiency), heart problems, bone marrow depression, kidney disease, liver disease, and treatment with chemotherapy or radiation. Some patients may experience increased sensitivity to light while taking ATUBRI 500MG TABLET, and avoiding prolonged exposure to sunlight is recommended. Consult your doctor if you are pregnant as ATUBRI 500MG TABLET can cause harmful effects on the unborn baby. Both women and men using ATUBRI 500MG TABLET should use birth control to avoid pregnancy. The use of ATUBRI 500MG TABLET by either parent may result in congenital disabilities. You should not take ATUBRI 500MG TABLET during breastfeeding. Use ATUBRI 500MG TABLET with caution in elderly patients. If you have had leukaemia (blood cancer) and are in remission, do not take live vaccines for three months after your last chemotherapy. You and your surrounding people, such as family members, should not take the polio vaccine. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) in contact with ATUBRI 500MG TABLET catches fire and burns easily. Washing clothing and bedding may reduce product build-up but not remove it.

verifiedApollotooltip
CapecitabineAdalimumab
Severe
CapecitabineWarfarin
Severe
CapecitabineAdalimumab
Severe
How does the drug interact with ATUBRI 500MG TABLET:
Co-administration of ATUBRI 500MG TABLET is taken with Adalimumab, which may increase the risk or severity of infections.

How to manage the interaction:
There may be a possibility of interaction between ATUBRI 500MG TABLET and Adalimumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include an enlarged spleen or liver, stomach pain, ongoing fever, excessive sweating at night, unexplained weight loss, complications, infection, fever, chills, diarrhea, a sore throat, muscle aches, difficulty breathing, or pain or discomfort while urinating. Do not stop using any medications without a doctor's advice.
CapecitabineWarfarin
Severe
How does the drug interact with ATUBRI 500MG TABLET:
Co-administration of Warfarin with ATUBRI 500MG TABLET can increase the effect of Warfarin.

How to manage the interaction:
Although there is a possible interaction between ATUBRI 500MG TABLET and Warfarin, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
CapecitabineThalidomide
Severe
How does the drug interact with ATUBRI 500MG TABLET:
Co-administration of Thalidomide with ATUBRI 500MG TABLET may increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction, ATUBRI 500MG TABLET can be taken with Thalidomide if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of blood clots such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness, or swelling in an arm or leg. Do not discontinue the medication without consulting a doctor.
CapecitabineTofacitinib
Severe
How does the drug interact with ATUBRI 500MG TABLET:
Co-administration of Tofacitinib with ATUBRI 500MG TABLET may increase the risk of serious and potential infections.

How to manage the interaction:
Although there is an interaction, ATUBRI 500MG TABLET can be taken with Tofacitinib if prescribed by the doctor. Consult the prescriber if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.
CapecitabineEtanercept
Severe
How does the drug interact with ATUBRI 500MG TABLET:
Co-administration of Etanercept with ATUBRI 500MG TABLET may increase the risk or severity of infection may increase.

How to manage the interaction:
Co-administration of Etanercept with ATUBRI 500MG TABLET can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
CapecitabineFolic acid
Severe
How does the drug interact with ATUBRI 500MG TABLET:
Co-administration of Folic acid with ATUBRI 500MG TABLET may increase the risk of serious side effects such as bleeding problems, anemia, infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Folic acid and ATUBRI 500MG TABLET, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, diarrhea, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling sensation in the hands and feet, contact a doctor. Do not discontinue the medication without consulting a doctor. Do not discontinue the medication without consulting a doctor.
CapecitabineBaricitinib
Severe
How does the drug interact with ATUBRI 500MG TABLET:
Co-administration of ATUBRI 500MG TABLET with Baricitinib may increase the risk of serious and potential infections.

How to manage the interaction:
Although there is an interaction, ATUBRI 500MG TABLET can be taken with Baricitinib if prescribed by the doctor. Consult the doctor if you develop fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.
CapecitabineFingolimod
Severe
How does the drug interact with ATUBRI 500MG TABLET:
Co-administration of Fingolimod with ATUBRI 500MG TABLET may increase the risk of serious and potential infections.

How to manage the interaction:
Although there is an interaction, ATUBRI 500MG TABLET can be taken with Fingolimod if prescribed by the doctor. Consult the prescriber if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.
CapecitabineDeferiprone
Severe
How does the drug interact with ATUBRI 500MG TABLET:
Co-administration of Deferiprone can lower white blood cell count, and combining it with ATUBRI 500MG TABLET may affect white blood cells or bone marrow function. This may lead to the development of serious infections.

How to manage the interaction:
Although there is an interaction, ATUBRI 500MG TABLET can be taken with Deferiprone if prescribed by the doctor. Consult the prescriber if you notice signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.
CapecitabineCertolizumab
Severe
How does the drug interact with ATUBRI 500MG TABLET:
Co-administration of ATUBRI 500MG TABLET is taken with Certolizumab, which may increase the risk or severity of infections.

How to manage the interaction:
Although taking ATUBRI 500MG TABLET and Certolizumab together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
verifiedApollotooltip
CAPECITABINE-500MGOther and unspecified infectious diseases
Severe
CAPECITABINE-500MGChronic ischaemic heart disease
Severe
CAPECITABINE-500MGOther and unspecified infectious diseases
Severe
How does the disease interact with ATUBRI 500MG TABLET:
Antineoplastic drugs regularly can, to variable degrees, promote myelosuppression due to their cytotoxic effects on rapidly growing tissues.

How to manage the interaction:
The use of ATUBRI 500MG TABLET may be contraindicated in patients with known infectious diseases. Consult the doctor if you notice signs or symptoms of infection such as fever, sore throat, or local infection during therapy. Close monitoring of hematopoietic function is recommended.
CAPECITABINE-500MGChronic ischaemic heart disease
Severe
How does the disease interact with ATUBRI 500MG TABLET:
Myocardial infarction, ischemia, angina, dysrhythmias, cardiac failure, sudden death, electrocardiographic abnormalities, and cardiomyopathy are just a few of the cardiotoxicity side effects that ATUBRI 500MG TABLET can produce.

How to manage the interaction:
Adverse reactions like heart attack, reduced blood flow, chest pain, irregular heartbeat, cardiac failure, sudden death, electrocardiographic changes and cardiomyopathy may be more common in patients with a prior history of coronary artery disease.
CAPECITABINE-500MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with ATUBRI 500MG TABLET:
Patients with significant renal impairment (creatinine clearance less than 30 mL/min) should not use ATUBRI 500MG TABLET.

How to manage the interaction:
ATUBRI 500MG TABLET is contraindicated in patients with severe renal impairment. Dose adjustment may be needed in patients with moderate renal impairment. Monitoring of adverse reactions and dose adjustment may be needed in patients with mild and moderate impairment.
  • BEVACIZUMAB
  • CISPLATIN
  • METRONIDAZOLE
  • CALCIUM LEUCOVORIN
  • ALLOPURINOL
  • CIMETIDINE
  • WARFARIN
  • COUMARINS
  • BRIVUDINE
  • SORIVUDINE
  • PHENYTOIN
No

  • Regularly monitor your blood tests to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. ATUBRI 500MG TABLET may make your skin sensitive to sunlight.
  • ATUBRI 500MG TABLET should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking ATUBRI 500MG TABLET.
  • Consult a doctor immediately if you notice any signs of infection, fever, diarrhoea, chills, etc.

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.
  • Get optimal sleep; rest well.

ATUBRI 500MG TABLET Substitute

Substitutes safety advice

  • Xeloda 500 mg Tablet 10's

    by Others

    ₹113.58per tablet

  • Capegard 500 Tablet 10's

    by Others

    ₹80.55per tablet

  • Capecite-500 Tablet 8's

    by Others

    ₹113.58per tablet

  • Capetero-500 Tablet 10's

    by Others

    ₹113.58per tablet

  • Capsy 500 Tablet 10's

    by Others

    ₹113.58per tablet
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