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Prescription drug
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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Composition :

APREMILAST-10MG

Manufacturer/Marketer :

Kaizen Research Labs India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIPSORIATICS

Country of origin

India

Manufacturer/Marketer address

Old No: 9/2, New No: 1/2, First Floor Jayammal Street, Shenoy Nagar Chennai Chennai Tn 600030 In
Other Info - ATL0017

FAQs

Disclaimer

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Alcohol

Caution

Limit intake of alcohol, as this may increase the risk of serious side effects.

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Pregnancy

Caution

If you are pregnant, inform your doctor before taking Atlast 10 Tablet . Consult your doctor if you become pregnant while taking Atlast 10 Tablet .

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Breast Feeding

Caution

It is not known whether Atlast 10 Tablet may pass into breast milk or not. If you are breastfeeding, inform your doctor before taking Atlast 10 Tablet .

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Driving

Safe if prescribed

Atlast 10 Tablet has no or negligible influence on the ability to drive and use machines.

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Liver

Caution

Atlast 10 Tablet to be taken with caution, especially if you have a history of liver problems. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

Atlast 10 Tablet to be taken with caution, especially if you have a history of kidney diseases. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Unsafe

Atlast 10 Tablet is not recommended for use in children and adolescents below 17 years.

About Atlast 10 Tablet

Atlast 10 Tablet belongs to a class of drugs known as phosphodiesterase 4 (PDE4) inhibitors. It is used to treat Plaque psoriasis (scaly, itchy, and red patches on the skin), psoriasis arthritis (inflammation in the joints in people with psoriasis), and oral ulcers. Psoriasis is a chronic, painful, nontransmissible, deactivating and damaging disease. It can happen at any age and is most common in the age group 50 to 69. Psoriatic arthritis is a type of arthritis that some people with psoriasis experience.

Atlast 10 Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor. Atlast 10 Tablet works by blocking the action of some chemical messengers that are responsible for inflammation related to psoriatic arthritis (inflammation in the joints in people with psoriasis) and psoriasis (scaly, itchy, and red patches on the skin), and thus, lowers the signs and symptoms of these conditions.

Take Atlast 10 Tablet as prescribed by your doctor. You are advised to take Atlast 10 Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience diarrhoea, vomiting, nausea, weight loss, and back pain. Most of these side effects of Atlast 10 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Atlast 10 Tablet should not be taken in the conditions like depression as it is getting worse with thoughts of suicide. Before starting Atlast 10 Tablet , please inform your doctor if you have any allergy to Atlast 10 Tablet and its part. Atlast 10 Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Atlast 10 Tablet . Atlast 10 Tablet does not affect the ability to drive and use machines.

Uses of Atlast 10 Tablet

Plaque psoriasis, psoriasis arthritis, and oral ulcers caused by Behcet's disease.

Medicinal Benefits Mweb

Medicinal Benefits

Atlast 10 Tablet is used in treating psoriatic arthritis; it decreases pain and swelling and may help improve flexibility in the affected joints. It is also used to treat moderate to severe plaque psoriasis (skin disease causes red, scaly patches to form on some areas of the body) in people who may benefit from medications). It is used to treat ulcers in the mouth in persons with Behcet's syndrome (a disease that results from blood vessel swelling in the body). Atlast 10 Tablet works by blocking the action of some chemical messengers responsible for inflammation related to psoriatic arthritis and psoriasis, thus lowering the signs and symptoms of these conditions.

Directions for Use

Take Atlast 10 Tablet as prescribed by your doctor. Your doctor determines the dose of the medicine based on your condition. Take Atlast 10 Tablet with or without food. Swallow the Atlast 10 Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Side Effects of Atlast 10 Tablet

  • Diarrhea
  • Vomiting
  • Nausea
  • Weight loss
  • Back pain

Drug Warnings

Inform your doctor before using Atlast 10 Tablet , if you have previously had an allergic reaction (hypersensitivity). Before starting Atlast 10 Tablet , please inform your doctor if you have depression and suicidal thoughts. Inform your doctor before taking Atlast 10 Tablet if you have severe kidney problems. Inform your doctor while taking Atlast 10 Tablet if you lose weight without meaning to. Atlast 10 Tablet should not be taken in conditions like severe diarrhoea, nausea, and vomiting. Atlast 10 Tablet not recommended for use in children and adolescents aged below 17 years. If you are pregnant or breastfeeding, ask your doctor for advice before taking this Atlast 10 Tablet . Patients with rare hereditary galactose intolerance problems, total lactase deficiency or glucose-galactose malabsorption should not take Atlast 10 Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Atlast 10 Tablet:
Taking Atlast 10 Tablet with carbamazepine can significantly reduce the blood levels of Atlast 10 Tablet, which may make the medication less effective.

How to manage the interaction:
Taking Atlast 10 Tablet with Carbamazepine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Atlast 10 Tablet:
Coadministration of Phenytoin with Atlast 10 Tablet may reduce the blood levels of Atlast 10 Tablet, which may reduce effectiveness in treatment.

How to manage the interaction:
Although taking Phenytoin and Atlast 10 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
ApremilastFosphenytoin
Severe
How does the drug interact with Atlast 10 Tablet:
Coadministration of Fosphenytoin with Atlast 10 Tablet may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Fosphenytoin and Atlast 10 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Atlast 10 Tablet:
Coadministration of Nevirapine with Atlast 10 Tablet may decrease the blood levels of Atlast 10 Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is a possible interaction between Atlast 10 Tablet and Nevirapine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Atlast 10 Tablet:
Taking Atlast 10 Tablet with rifampicin can decrease the blood levels of Atlast 10 Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Atlast 10 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ApremilastMitotane
Severe
How does the drug interact with Atlast 10 Tablet:
Coadministration of Mitotane with Atlast 10 Tablet may reduce the effectiveness of treatment.

How to manage the interaction:
Although taking Atlast 10 Tablet and Mitotane together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atlast 10 Tablet:
Coadministration of Atlast 10 Tablet with primidone may decrease the blood levels of Atlast 10 Tablet, which may make Atlast 10 Tablet less effective in treating.

How to manage the interaction:
Although there is an interaction between Primidone and Atlast 10 Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ApremilastEnzalutamide
Severe
How does the drug interact with Atlast 10 Tablet:
Coadministration of Enzalutamide with Atlast 10 Tablet may reduce the efficacy of treatment.

How to manage the interaction:
Although taking Atlast 10 Tablet and Enzalutamide together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Atlast 10 Tablet:
Coadministration of Atlast 10 Tablet and Rifabutin may reduce the blood levels of Atlast 10 Tablet.

How to manage the interaction:
Although there is a possible interaction between Atlast 10 Tablet and Rifabutin, you can take these medicines together if prescribed by a doctor. In case you experience any symptoms, consult a doctor. Do not discontinue any medications without consulting a doctor.
ApremilastRifapentine
Severe
How does the drug interact with Atlast 10 Tablet:
Rifapentine may decrease the blood levels of Atlast 10 Tablet, which may make Atlast 10 Tablet less effective in treating the condition.

How to manage the interaction:
Although taking Atlast 10 Tablet and Rifapentine together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Habit Forming

No

Special Advise

  • Atlast 10 Tablet is a well-tolerated medicine. Mild stomach upset may arise early during the treatment.
  • Monitor your weight repeatedly as Atlast 10 Tablet may lead to weight loss.
  • Inform your doctor immediately if you experience new or worsened depression, suicidal thoughts, unexplained weight loss, or other mood changes.

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

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