Amlosafe-LS 5/5 Tablet 10's

Amlosafe-LS 5/5 Tablet 10's belongs to the class of 'anti-hypertensive drugs', primarily used to treat hypertension (high blood pressure). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against blood vessels' walls. This condition makes the heart work harder in pumping blood to the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack, and kidney failure.

Amlosafe-LS 5/5 Tablet 10's is a combination of medicine that consists of Amlodipine (calcium channel blocker) and Lisinopril (angiotensin-converting enzyme inhibitor). Amlodipine belongs to the class of 'calcium channel blockers and is used to treat high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, lowering blood pressure. Amlodipine also improves blood supply to the heart muscle to receive more oxygen and thus preventing chest pain. Lisinopril belongs to the class of 'Angiotensin-Converting Enzyme (ACE) Inhibitors.' It relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, lowering blood pressure. Lisinopril also decreases the body’s production of certain substances that raise blood pressure.

Amlosafe-LS 5/5 Tablet 10's is an orally administered drug in the form of a tablet and capsule. You can take Amlosafe-LS 5/5 Tablet 10's with food or without food. Swallow it as a whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you how often you take Amlosafe-LS 5/5 Tablet 10's based on your medical condition. In some cases, you may experience blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck and trunk), dizziness, headache, and swelling of the ankles or feet. Most of these side effects of Amlosafe-LS 5/5 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please contact your doctor.

Do not stop taking Amlosafe-LS 5/5 Tablet 10's without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Regular monitoring of blood pressure, electrolyte levels and kidney functioning is advised while taking Amlosafe-LS 5/5 Tablet 10's. Inform your doctor if you are suffering from kidney, liver or heart diseases. Please tell your doctor if you are taking other medicines or allergic to Amlosafe-LS 5/5 Tablet 10's. Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Let your doctor know if you use any prescription and non-prescription medications you are taking, including vitamins, before starting Amlosafe-LS 5/5 Tablet 10's. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Amlosafe-LS 5/5 Tablet 10's can be prescribed accordingly.

Amlosafe-LS 5/5 Tablet 10's treats hypertension (high blood pressure) and consists of Amlodipine (calcium channel blocker) and Lisinopril (angiotensin-converting enzyme inhibitor). Amlodipine is a 'calcium channel blocker' and treats high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, lowering blood pressure. It also treats chest pain by improving the blood supply to the heart muscle to receive more oxygen. Amlodipine also improves a person's tolerance to exercise and keeps the blood pressure at acceptable levels. Lisinopril is an 'Angiotensin-Converting Enzyme (ACE) Inhibitor.' It relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, lowering blood pressure.

• Confusion
• Sweating
• Tiredness
• Dizziness
• Headache
• Blurred vision
• Stomach upset
• Swelling of the ankles or feet
• Flushing (sense of warmth in the face, ears, neck and trunk)

• Do not use Amlosafe-LS 5/5 Tablet 10's if you are allergic to Amlosafe-LS 5/5 Tablet 10's or its components.
• Please inform your doctor if you are using any prescription and non-prescription medications, including vitamins, before starting Amlosafe-LS 5/5 Tablet 10's.
• Let your doctor know if you have any history of severe heart, kidney or liver diseases, high potassium levels (hyperkalaemia), bone marrow suppression, and aortic stenosis (heart valve problem). 
• It is essential to inform your doctor if you are a breastfeeding mother before using Amlosafe-LS 5/5 Tablet 10's since Amlodipine may pass into the breast milk.
• Lisinopril is not recommended during pregnancy since it harms the unborn baby. Please ask your doctor if you plan to conceive or are pregnant before using Amlosafe-LS 5/5 Tablet 10's.
• Amlosafe-LS 5/5 Tablet 10's can increase the chances of light-headedness so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness.

Drug-Drug Interactions: Amlosafe-LS 5/5 Tablet 10's may interact with drugs reducing cholesterol (simvastatin), corticosteroids (prednisolone), painkillers (ibuprofen, naproxen), anti-hypertensive drugs (ramipril, metoprolol, bendroflumethiazide), drugs treating impotence (sildenafil), gout medicine (allopurinol), diabetic drugs (Insulin glargine, metformin, sitagliptin), water pills (furosemide), and fits medicine (pregabalin).

Drug-Food Interactions: Amlosafe-LS 5/5 Tablet 10's may interact or have decreased effect when used with alcohol and high potassium foods.

Drug-Disease Interactions: Before using Amlosafe-LS 5/5 Tablet 10's, let your doctor know if have heart, kidney or liver diseases, high potassium levels (hyperkalaemia), bone marrow suppression, and aortic stenosis (heart valve problem).

• SIMVASTATIN
• PREDNISOLONE
• BENDROFLUMETHIAZIDE
• NAPROXEN
• INSULIN GLARGINE
• PREGABALIN
• SITAGLIPTIN
• ALLOPURINOL
• SILDENAFIL
• METOPROLOL
• RAMIPRIL
• FUROSEMIDE
• IBUPROFEN
• METFORMIN

• Keep your weight under control with body mass index (BMI) between 19.5 and 24.9.
• Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm of Hg.
• Limit sodium chloride intake (table salt) in your daily diet to 2300 mg daily or less than 1500 mg is ideal for most adults.
• If you are taking alcohol, use only one serving for women and two servings for men.
• Quit smoking to lower the risk of heart disease.
• Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress.
• Monitor your blood pressure daily, and if you notice any fluctuations frequently, please contact your doctor immediately.
• Try including heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

• Monitor your blood pressure regularly and seek medical advice if you notice any drastic fluctuations.
• Amlosafe-LS 5/5 Tablet 10's may affect patients with hepatic impairment, and hence it is used cautiously, and Liver function monitoring and Liver Function Tests are advised to monitor the liver enzyme changes.
• Your doctor may advise you to get a regular kidney function test and blood examinations for potassium levels and other electrolytes while using Amlosafe-LS 5/5 Tablet 10's to rule out any renal impairment.

Hypertension: When your blood pressure is too high, you have a chronic condition. The amount of blood pumped by the heart and the amount of resistance exerted by the arteries against the blood flow is called blood pressure. When the heart pumps more blood, the arteries narrow, and the blood pressure rises. Uncontrolled blood pressure can lead to serious heart problems such as stroke and heart attack. High blood pressure can also damage the brain (stroke) and lead to kidney failure. The systolic and diastolic pressures of blood are measured. The contraction and relaxation of the heart are represented by systolic blood pressure. Diastolic pressure is exerted in the blood vessels when the heart is at rest and not beating. The ideal blood pressure range is 90/60 mmHg to 120/80 mmHg. When systolic blood pressure exceeds 140mmHg, and diastolic pressure exceeds 90mmHg, hypertension is diagnosed. Hypertension symptoms include headaches, nosebleeds, vomiting, and chest pain.