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Written By ,
Reviewed By Sunny S , MBBS

Composition :

ROSUVASTATIN-40MG

Manufacturer/Marketer :

Fusion Health Care Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[ANTILIPEMICS]

Country of origin

India

Manufacturer/Marketer address

Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034
Other Info - ADV0092

FAQs

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

You are recommended not to consume alcohol along with ADVASTAT-40MG TABLETS to avoid unpleasant side-effects like drowsiness, dizziness, or sleepiness. It may also lead to a life-threatening condition like coma if taken with excessive alcohol.

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Pregnancy

Consult your doctor

ADVASTAT-40MG TABLETS can have some harmful effects on the baby (foetus), so your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Consult your doctor

ADVASTAT-40MG TABLETS is known to pass into the breast milk and may cause some degree of sedation in the baby. So, if you note any of the following signs in the baby let your doctor know about this.

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Driving

Safe if prescribed

ADVASTAT-40MG TABLETS does not usually affect your ability to drive.

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Liver

Consult your doctor

ADVASTAT-40MG TABLETS to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Consult your doctor

ADVASTAT-40MG TABLETS to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

ADVASTAT-40MG TABLETS can be prescribed in the children (aged 8 years or more) suffering from familial hypercholesterolemia (a genetic disease resulting in high cholesterol) along with lipid-lowering pills and other dietary measures.

About ADVASTAT-40MG TABLETS

ADVASTAT-40MG TABLETS belongs to the class of medicines known as statins, which reduces bad cholesterol (low-density lipoprotein-LDL) and glyceride level, thereby reducing the risk of heart attack and stroke in the future. High cholesterol, known as hyperlipidemia or dyslipidemia, occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high cholesterol level in the blood, your arteries get narrowed and clogged, finally contributing to heart diseases like stroke and heart attack. 

ADVASTAT-40MG TABLETS works by blocking liver enzymes, causing the liver to make less cholesterol. ADVASTAT-40MG TABLETS increases the uptake and breakdown by the liver of cholesterol already in the blood. Thus, ADVASTAT-40MG TABLETS lowers the levels of lipids known as cholesterol and triglycerides in the blood when lifestyle changes (like a low-fat diet) on their own have failed. ADVASTAT-40MG TABLETS reduces the ‘bad’ cholesterol and increases the ‘good’ cholesterol by blocking our body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood.

The possible side effects of ADVASTAT-40MG TABLETS may include myalgia (muscle pain), asthenia (lack of energy), nausea, headache, abdominal pain, muscle pain, weakness, and daytime drowsiness. Most of these side effects of ADVASTAT-40MG TABLETS do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. It is important to have your lipid profile checked regularly.

This medicine is only one part of a treatment program that should include a healthy low-fat diet, regular exercise, smoking cessation, moderation of alcohol intake and weight reduction. You can normally eat while taking this medicine but avoid high-fat foods. Before starting the dose of ADVASTAT-40MG TABLETS , tell your doctor if you have kidney problems, are pregnant or breastfeeding, diabetes, severe lung disease, or musculoskeletal disorder (like myopathy and rhabdomyolysis). You should avoid taking ADVASTAT-40MG TABLETS with immune system affecting medicine (cyclosporine) or anti-HIV medicines (lopinavir, ritonavir, or atazanavir) as it might have a serious effect.

Uses of ADVASTAT-40MG TABLETS

Hyperlipidemia (high cholesterol), Prevention of heart attack, Prevention of stroke.

Medicinal Benefits Mweb

Key Benefits

ADVASTAT-40MG TABLETS lowers the risk of cardiovascular disease and coronary events like heart attack, stroke, and heart-related chest pain (angina). ADVASTAT-40MG TABLETS is beneficial in patients who are at high risk of these events. It is also prescribed in children (aged eight years or more) suffering from familial hypercholesterolemia (a genetic disease resulting in high cholesterol) along with lipid-lowering pills and other dietary measures. ADVASTAT-40MG TABLETS plays a vital role in slowing atherosclerosis progress (blocked artery walls of heart due to fat/lipid deposition leading to heart attack and stroke) in adult patients.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it. Sprinkle Capsule: The capsule should be consumed whole. Do not chew or crush. For patients who have trouble swallowing, open the capsule and sprinkle the contents over a small amount (tablespoon) of soft food (curd, honey, tomato ketchup, vanilla and chocolate flavour pudding) and consume it.

Side Effects of ADVASTAT-40MG TABLETS

Drug Warnings

A prolonged intake of ADVASTAT-40MG TABLETS may cause muscular disorders like myopathy and rhabdomyolysis with kidney damage. A person taking excess alcohol and affected with liver disease should consult a doctor before its intake. Caution should be exercised if you are taking any blood thinner or anticoagulants like warfarin or coumarin. At least 2 hours gap should be maintained between intake of ADVASTAT-40MG TABLETS and antacids like magnesium hydroxide and aluminium hydroxide. Increases in HbA1c and fasting glucose levels can be observed if a person regularly takes ADVASTAT-40MG TABLETS . So you should tell the doctor before having these diabetes tests. Patients with proteinuria (protein in urine) or haematuria (blood in urine) should tell the doctor before taking the ADVASTAT-40MG TABLETS , as it might require dose adjustment. It is recommended that you should have a liver enzyme test regularly if you are regularly taking ADVASTAT-40MG TABLETS .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Advastat 40 mg Tablet:
Taking Advastat 40 mg Tablet with Posaconazole can increase the blood levels of Advastat 40 mg Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Advastat 40 mg Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Advastat 40 mg Tablet:
Coadministration of Nicotinamide with Advastat 40 mg Tablet can increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage.

How to manage the interaction:
Taking Nicotinamide with Advastat 40 mg Tablet together is used with caution as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
AtorvastatinTelithromycin
Severe
How does the drug interact with Advastat 40 mg Tablet:
Using Advastat 40 mg Tablet together with telithromycin may significantly increase the blood levels of Advastat 40 mg Tablet.

How to manage the interaction:
Taking Telithromycin with Advastat 40 mg Tablet together can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.
AtorvastatinNefazodone
Severe
How does the drug interact with Advastat 40 mg Tablet:
Using Advastat 40 mg Tablet together with nefazodone may significantly increase the blood levels of Advastat 40 mg Tablet.

How to manage the interaction:
Taking Advastat 40 mg Tablet with Nefazodone together can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
How does the drug interact with Advastat 40 mg Tablet:
Taking Advastat 40 mg Tablet with indinavir may considerably raise Advastat 40 mg Tablet levels in the blood.

How to manage the interaction:
Taking Advastat 40 mg Tablet and indinavir together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinTroleandomycin
Severe
How does the drug interact with Advastat 40 mg Tablet:
Using Advastat 40 mg Tablet together with troleandomycin may significantly increase the blood levels of Advastat 40 mg Tablet.

How to manage the interaction:
Taking Advastat 40 mg Tablet with Troleandomycin together can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
How does the drug interact with Advastat 40 mg Tablet:
Coadministration of Erlotinib with Advastat 40 mg Tablet can raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Erlotinib with Advastat 40 mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Advastat 40 mg Tablet:
Using Advastat 40 mg Tablet together with itraconazole may significantly increase the blood levels of Advastat 40 mg Tablet.

How to manage the interaction:
Coadministration of Advastat 40 mg Tablet along with itraconazole together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not discontinue any medication without consulting a doctor.
AtorvastatinFosamprenavir
Severe
How does the drug interact with Advastat 40 mg Tablet:
Using Advastat 40 mg Tablet together with fosamprenavir may significantly increase the blood levels of Advastat 40 mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Advastat 40 mg Tablet and Fosamprenavir, you can take these medicines together if prescribed by a doctor. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.
AtorvastatinNelfinavir
Severe
How does the drug interact with Advastat 40 mg Tablet:
Taking Advastat 40 mg Tablet with nelfinavir may considerably raise Advastat 40 mg Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Although taking Advastat 40 mg Tablet and cyclosporine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

Habit Forming

No

Special Advise

  • Your doctor may advise on regular monitoring of liver function tests to monitor the liver enzymes.

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