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Acutrol C 400 Tablet 15's

Acutrol C 400 Tablet 15's

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Written ByUrvashi Bharti,MBBS
Reviewed ByBayyarapu Mahesh Kumar,M Pharmacy
Last Updated Aug 20, 2024 | 12:51 PM IST

About Acutrol C 400 Tablet 15's

Acutrol C 400 Tablet 15's belongs to a group of medications called phosphate binder (which decreases the level of phosphate in the body). It is primarily used to control high phosphate levels in the body (hyperphosphataemia) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine), and patients with chronic kidney disease. It is also used for the treatment of bone disease.

Acutrol C 400 Tablet 15's contains sevelamer that works by binding phosphate in the gastrointestinal tract and decreasing absorption. It effectively reduces excess phosphate levels in the blood, prevents the unsafe build-up of phosphate in your body, helps keep your bones strong, and decreases the risk of heart disease and strokes.

Take Acutrol C 400 Tablet 15's exactly as directed by your doctor. The most common side effects of Acutrol C 400 Tablet 15's are vomiting, upper abdominal pain, nausea, diarrhoea, stomach ache, indigestion, and flatulence. However, if the side effects persist, contact your doctor.

The use of Acutrol C 400 Tablet 15's is restricted in persons with a known history of allergic to any of the ingredients present in this medicine, have low levels of phosphate in their blood, and have a bowel obstruction. Acutrol C 400 Tablet 15's contains lactose (milk sugar). If you have an intolerance to some sugars, contact your doctor before taking Acutrol C 400 Tablet 15's. Tell your doctor if you are facing swallowing problems, motility (movement) in your stomach and bowel, being sick frequently, active inflammation of the bowel,  have undergone major surgery on your stomach or bowel, or have serious inflammatory bowel disease. If you are pregnant or breastfeeding, please consult your doctor before taking Acutrol C 400 Tablet 15's.

Uses of Acutrol C 400 Tablet 15's

Hyperphosphatemia (high phosphorus level in blood)

Medicinal Benefits

Acutrol C 400 Tablet 15's belongs to a group of medications called phosphate binder, which works by binding phosphate in the gastrointestinal tract and decreasing its absorption. This lowers the phosphate concentration in the body. It effectively reduces excess phosphate levels in the blood, prevents the unsafe buildup of phosphate in your body, helps keep your bones strong, and decreases the risk of heart disease and strokes. Acutrol C 400 Tablet 15's controls hyperphosphataemia (high blood phosphate levels) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine) or peritoneal dialysis (where the fluid is pumped into the abdomen and an internal body membrane filters the blood), and patients with chronic kidney disease.

Directions for Use

Tablet: Acutrol C 400 Tablet 15's should be taken as prescribed by the doctor. Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Take Acutrol C 400 Tablet 15's as prescribed by the doctor. Before taking, disperse the tablet in the prescribed amount of water, mix well and then swallow it. Do not crush, chew or swallow as a whole.Powder/granules: Firstly, shake the container and open the cap. Add the powder of the packet to a cup containing two teaspoonfuls (30 ml) of water. Mix well and make your child drink within 30 minutes. It is advised not to give more than the prescribed dose of medicine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Acutrol C 400 Tablet 15's

  • Headache
  • Diarrhoea
  • Stomach upset
  • Constipation

Drug Warnings

You should avoid taking Acutrol C 400 Tablet 15's if you are allergic to Acutrol C 400 Tablet 15's. Speak to your doctor if you have swallowing disorders, digestive tract surgery, severe constipation, have undergone major surgery on your stomach or bowel, or have serious inflammatory bowel disease. It should be used with caution if you are pregnant or planning to become pregnant. Acutrol C 400 Tablet 15's should not be recommended for breastfeeding mothers as it passes into breast milk. Avoid alcohol consumption while taking Acutrol C 400 Tablet 15's as it might cause unpleasant side effects. The safety and effectiveness of children under six years of age have not been established, so a Acutrol C 400 Tablet 15's should not be given to them. Acutrol C 400 Tablet 15's contains lactose (milk sugar). If you have an intolerance to some sugars, contact your doctor before taking Acutrol C 400 Tablet 15's. Regular monitoring of serum phosphate levels, vitamin D, A, E, K, and folic acid is advised while taking Acutrol C 400 Tablet 15's.

Therapeutic Class

HYPOPHOSPHATEMIC AGENT

Drug Interactions

Drug-Drug Interactions: Acutrol C 400 Tablet 15's interacts with antibiotics (ciprofloxacin), immunosuppressive agents (mycophenolate), thyroid medications  (levothyroxine), and medication used to treat bladder cancer (erdafitinib).

Drug-Food Interactions: Avoid taking high-phosphate additives and alcohol as this makes it harder for your body to absorb Acutrol C 400 Tablet 15's and increases side effects. Using Acutrol C 400 Tablet 15's together with multivitamins with minerals may decrease the effects of multivitamins with minerals. So, Multivitamins with minerals should be administered at least 4 hours before Acutrol C 400 Tablet 15's.

Drug-Disease Interactions: The use of Acutrol C 400 Tablet 15's is restricted in people with hypophosphatemia (low phosphate level in blood), bowel obstruction and perforation, and severe liver disease.

Drug-Drug Interactions Checker List

  • CIPROFLOXACIN
  • MYCOPHENOLATE SODIUM
  • LEVOTHYROXINE SODIUM
  • ERDAFITINIB

Habit Forming

No

Diet & Lifestyle Advise

  • Take fresh fruits, vegetables, rice, milk, un-enriched corn and rice cereals, and soda without phosphate additives in your regular diet.
  • Avoid or limit high phosphorus addictive foods (processed meats, instant puddings, sauces, spreadable cheeses, and beverage products).
  •  Avoid intake of alcoholic beverages with Acutrol C 400 Tablet 15's as it can make you dehydrated and may increase the side effects. 
  • Make sure you drink plenty of fluids. This will help you clear out the extra phosphate and will help you overcome some.
  • Acutrol C 400 Tablet 15's is preferably taken with meals as it can bind to dietary phosphate and prevent its absorption into the bloodstream. Drink it with a full glass of water.
  • Do not stop taking the Acutrol C 400 Tablet 15's dose until your doctor says so.
  • Do not use Acutrol C 400 Tablet 15's if you have a history of bowel obstruction.

Special Advise

  • Regular monitoring of serum phosphate levels, vitamin D, A, E, K, and folic acid is recommended while taking Acutrol C 400 Tablet 15's.

Disease/Condition Glossary

Hyperphosphatemia: Hyperphosphatemia is defined as an increased phosphate level in the blood. This condition is often a complication of chronic kidney disease. Phosphate is an important electrolyte. It strengthens your bones and teeth and produces energy.  When phosphate levels increase in the blood due to kidney impairment (the kidney does not remove extra phosphate out of the body), this can cause muscle problems and increase the risk of weak bones, heart attacks, and strokes. It is more common in people with chronic kidney disease and people on dialysis. Symptoms may include itchy skin, red eyes, bone pain, and fractures.

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