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  3. ACTMIN 650MG TABLET

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Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:29 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Drug Interactions Checker List

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Drug-Drug Interactions

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ParacetamolOxazepam
Severe
ParacetamolKetamine
Severe

Drug-Drug Interactions

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ParacetamolOxazepam
Severe
How does the drug interact with Actmin 650mg Tablet:
Co-administration of Actmin 650mg Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Actmin 650mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolKetamine
Severe
How does the drug interact with Actmin 650mg Tablet:
Co-administration of ketamine and Actmin 650mg Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Actmin 650mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolTeriflunomide
Severe
How does the drug interact with Actmin 650mg Tablet:
Co-administration of Teriflunomide with Actmin 650mg Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Actmin 650mg Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Actmin 650mg Tablet:
Co-administration of Actmin 650mg Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Actmin 650mg Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolLeflunomide
Severe
How does the drug interact with Actmin 650mg Tablet:
Co-administration of Actmin 650mg Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Actmin 650mg Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Actmin 650mg Tablet:
Co-administration of Actmin 650mg Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Actmin 650mg Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Actmin 650mg Tablet:
Co-administration of Lomitapide and Actmin 650mg Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Actmin 650mg Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Actmin 650mg Tablet:
Co-administration of Mipomersen with Actmin 650mg Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Actmin 650mg Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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ACETAMINOPHEN-650MGMental and behavioural disorders due to use of alcohol
Severe
ACETAMINOPHEN-650MGHepatic failure, not elsewhere classified
Severe

Drug-Diseases Interactions

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ACETAMINOPHEN-650MGMental and behavioural disorders due to use of alcohol
Severe
How does the disease interact with Actmin 650mg Tablet:
Chronic alcoholics may have a higher risk of hepatotoxicity when using Actmin 650mg Tablet. Patients using Actmin 650mg Tablet may cause severe liver damage, including acute liver failure that required a liver transplant and resulted in death.

How to manage the interaction:
Actmin 650mg Tablet should be used with caution in patients who consume three or more alcoholic drinks a day. Avoid alcohol consumption while taking Actmin 650mg Tablet. If you have nausea, vomiting, fever, rash, anorexia (eating disorder), over-tiredness, upper right stomach pain, dark urine, and jaundice, contact your doctor as these may be signs and symptoms of liver injury.
ACETAMINOPHEN-650MGHepatic failure, not elsewhere classified
Severe
How does the disease interact with Actmin 650mg Tablet:
The liver predominantly converts Actmin 650mg Tablet to inactive forms. Patients with hepatic impairment may be more prone to toxicity because their minor metabolic pathways are more active.

How to manage the interaction:
Actmin 650mg Tablet should be used with caution in patients with kidney insufficiency. Also, it is recommended to avoid drinking alcohol while taking Actmin 650mg Tablet.

Drug Warnings

Do not take ACTMIN 650MG TABLET if you're allergic to any ingredient in it. Caution should be exercised while using ACTMIN 650MG TABLET in children. If you are pregnant or breastfeeding, please consult a doctor before using ACTMIN 650MG TABLET. Avoid alcohol consumption with ACTMIN 650MG TABLET as it may increase the risk of liver damage. If you have an impaired nutritional state caused by anorexia (eating disorder), wrong nutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking ACTMIN 650MG TABLET. Avoid taking more than recommended doses as it may increase the risk of serious liver damage.

Side Effects of ACTMIN 650MG TABLET

  • Nausea
  • Stomach pain
  • Dark coloured urine

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Chewable tablets: Chew the tablet completely and swallow. Do not swallow it as a whole.Orally disintegrating Tablet: Keep the tablet in the mouth and allow it to disintegrate. Do not swallow as a whole. Avoid handling the strip with wet hands.Oral Suspension/Paed drops: Shake the bottle well before each use. Take the recommended dose by mouth using the measuring cup/dosing syringe/dropper.Effervescent Tablets/Dispersible Tablets/Soluble Tablets: Check the label for directions before use. Disperse the tablet in the recommended amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Medicinal Benefits Mweb

Medicinal Benefits

ACTMIN 650MG TABLET contains acetaminophen, an analgesic (pain killer) and antipyretic (reduces fever). It inhibits the production of certain chemical messengers in the brain known as prostaglandins. Thus, reducing pain. Also, ACTMIN 650MG TABLET affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thereby, it reduces fever.

Uses of ACTMIN 650MG TABLET

Fever, Pain relief.

About ACTMIN 650MG TABLET

ACTMIN 650MG TABLET belongs to the group of medicines called analgesics (pain killers), and antipyretics (fever-reducing agents) used to reduce fever and treat mild to moderate pain. Also, it is used to relieve headaches, migraine, toothache, period pain, back pain, muscle pain and rheumatic pains. Pain and fever are caused by the activation of pain receptors due to the release of certain natural chemicals in the body, like prostaglandin.

ACTMIN 650MG TABLET contains acetaminophen that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins. Thus, reducing pain. Also, ACTMIN 650MG TABLET affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thereby it reduces fever.

Take ACTMIN 650MG TABLET as recommended. In some cases, ACTMIN 650MG TABLET may cause side effects such as nausea, stomach pain and dark-coloured urine. Most of these side effects of ACTMIN 650MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take ACTMIN 650MG TABLET if you're allergic to any ingredient in it. ACTMIN 650MG TABLET is not recommended for children below six years of age. If you are pregnant or breastfeeding, please consult a doctor before using the ACTMIN 650MG TABLET. Avoid alcohol consumption with ACTMIN 650MG TABLET as it may increase the risk of liver damage. If you have an impaired nutritional state caused by anorexia (eating disorder), malnutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking the ACTMIN 650MG TABLET.

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:29 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

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Side effects of Actmin 650mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

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Side Effects

Common Side Effects
  • Nausea
  • Vomiting
  • Increased Aspartate Aminotransferase (AST) In Blood
  • Stomach Pain
  • Anemia
  • Rash
  • Shortness Of Breath

Consult you doctor in case you face the following side effects
  • Bleeding After Surgery
  • High Blood Pressure
  • High Blood Sugar
  • Accumulation Of Fluid Around Lungs

If any of the above side effects continue or intensify, seek medical advice. Professional guidance may be necessary for appropriate care and treatment adjustments.
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