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Acetamide 250 mg Tablet 10's

Acetamide 250 mg Tablet 10's

aditya

Written BySantoshini Reddy G,M Pharmacy
Reviewed ByHari Kumar,MBBS
Last Updated Aug 20, 2024 | 1:09 PM IST

About Acetamide 250 mg Tablet 10's

Acetamide 250 mg Tablet 10's belongs to a group of medicines called carbonic anhydrase inhibitors used to treat glaucoma, oedema (fluid retention), epilepsy, and to treat and prevent altitude/mountain sickness. Glaucoma is an eye condition that causes damage to the optic nerve due to abnormally increased pressure in the eye. Epilepsy is a disorder of the nervous system due to disturbed nerve cell activity in the brain. Fluid retention is a condition in which fluids are accumulated in the body tissues.
 
Acetamide 250 mg Tablet 10's contains ‘acetazolamide’, which inhibits carbonic anhydrase enzyme. This inhibitory action decreases the secretion of aqueous humour, thereby lowers intraocular pressure. Acetamide 250 mg Tablet 10's inhibits the carbonic anhydrase enzyme; this helps retard abnormal, excessive discharge from central nervous system neurons, thereby helps treat certain dysfunctions of the central nervous system such as epilepsy. Acetamide 250 mg Tablet 10's reduces the activity of carbonic anhydrase, thereby helps lower fluid retention.
 
You are advised to take Acetamide 250 mg Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, vomiting, diarrhoea, headache, and increased urination. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Avoid taking Acetamide 250 mg Tablet 10's if you are pregnant, think you are pregnant or planning for pregnancy. Consult your doctor if you are breastfeeding. Acetamide 250 mg Tablet 10's is not recommended for children as safety and effectiveness have not been established. Acetamide 250 mg Tablet 10's might cause dizziness and drowsiness; so, drive only if you are alert. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

Uses of Acetamide 250 mg Tablet 10's

Glaucoma, Fluid retention/oedema, Epilepsy/seizures, Mountain sickness.

Medicinal Benefits

Acetamide 250 mg Tablet 10's belongs to a group of medicines called carbonic anhydrase inhibitors used to treat glaucoma, oedema (fluid retention), epilepsy, and to treat and prevent altitude/mountain sickness. Acetamide 250 mg Tablet 10's works by inhibiting the carbonic anhydrase enzyme. This inhibitory action decreases the secretion of aqueous humour, thereby lowering intraocular pressure. Acetamide 250 mg Tablet 10's inhibits the carbonic anhydrase enzyme; this helps retard abnormal, excessive discharge from central nervous system neurons, thereby helps treat certain dysfunctions of the central nervous system, such as epilepsy. Acetamide 250 mg Tablet 10's reduces the activity of carbonic anhydrase, thereby helping lower fluid retention. Acetamide 250 mg Tablet 10's may also be used to treat muscle weakness/periodic paralysis and to lower the increased pressure in the areas surrounding the spinal cord and brain.

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Acetamide 250 mg Tablet 10's

  • Headache
  • Nausea
  • Vomiting
  • Diarrhoea
  • Increased urination
  • Loss of appetite
  • Dizziness

Drug Warnings

Do not take Acetamide 250 mg Tablet 10's if you are allergic to any of its contents; if you have severe kidney/liver problems, chronic non-congestive angle-closure glaucoma, Addison’s disease, if you have low sodium and/or potassium levels or high chlorine levels. Inform your doctor if you have lung problems, kidney stones, electrolyte imbalance, adrenal gland problems, diabetes, or heart problems. Avoid taking Acetamide 250 mg Tablet 10's if you are pregnant, think you are pregnant or planning for pregnancy. Consult your doctor if you are breastfeeding. Acetamide 250 mg Tablet 10's is not recommended for children as safety and effectiveness have not been established. Acetamide 250 mg Tablet 10's might cause dizziness and drowsiness; so, drive only if you are alert. Acetamide 250 mg Tablet 10's might make your skin sensitive to sunlight; therefore, wear protective clothing and sunscreen whilst going out.

Therapeutic Class

ANTIGLAUCOMA AGENTS

Drug Interactions

Drug-Drug Interactions: Acetamide 250 mg Tablet 10's may have interaction with cardiac glycoside (digoxin), blood thinner (warfarin), anti-diabetic (metformin, gliclazide), anti-convulsant (phenytoin, primidone, carbamazepine, topiramate), steroid (prednisolone), anti-glaucoma agents (dorzolamide, brinzolamide), anti-arrhythmic (quinidine), anti-maniac (lithium), immunosuppressant (ciclosporin), alkalinizing agent (sodium bicarbonate), and anti-hypertensive medicines.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have severe kidney/liver problems, chronic non-congestive angle-closure glaucoma, Addison’s disease, low sodium and/or potassium levels, or high chlorine levels.

Drug-Drug Interactions Checker List

  • DIGOXIN
  • WARFARIN
  • METFORMIN
  • GLICLAZIDE
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • TOPIRAMATE
  • PREDNISOLONE
  • DORZOLAMIDE
  • BRINZOLAMIDE
  • QUINIDINE
  • LITHIUM
  • CICLOSPORIN
  • SODIUM BICARBONATE

Habit Forming

No

Diet & Lifestyle Advise

GLAUCOMA:

  • Avoid intake of baked foods such as cakes, cookies, doughnuts or fried items such as French fries and stick margarine as these foods may worsen glaucoma and damage the optic nerve.
  • Limit coffee intake as it may increase pressure in the eye. Replace coffee with green tea.
  • Avoid exercises such as any position where the head is lower than the body, like an inverted yoga pose, as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients.

EPILEPSY:

  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan to help those around you know what to do.
  • Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

FLUID RETENTION:

  • Limit salt intake.
  • Consume foods rich in magnesium, such as nuts, dark chocolate, whole grains, and leafy vegetables.
  • Include foods rich in vitamin B6, such as potatoes, bananas, meat, and walnuts.
  • Potassium reduces water retention, therefore, include potassium-rich foods such as avocados, tomatoes, and bananas.
  • Avoid refined carbohydrates.
  • Walking can help reduce fluid retention.

Special Advise

  • If you are due to have any surgery, inform the doctor/surgeon that you are taking Acetamide 250 mg Tablet 10's.
  • Your doctor may advise frequent blood tests whilst taking Acetamide 250 mg Tablet 10's.
  • Regular monitoring of serum electrolyte levels is advised.
  • Talk to your doctor immediately if you have thoughts of harming or killing yourself.

Disease/Condition Glossary

Glaucoma: It is an eye condition that causes damage to the optic nerve (essential for good vision) due to abnormally increased pressure in the eye. If it is not treated in time, it may cause blindness. Usually, there are no symptoms for glaucoma initially, except the slow loss of vision gradually. However, some symptoms include visible rainbow-coloured circles around bright lights or blurred vision. Rarely, glaucoma can develop suddenly with intense pain in the eye, visual disturbance or nausea.

Epilepsy/Seizures: Seizures, also known as fits or convulsions, are a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness. 

Fluid retention/oedema: It is a condition in which fluids are accumulated in the body tissues. Symptoms include bloating, weight fluctuations, puffiness of the face, abdomen, and hips, and swollen legs, ankles, and feet.

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